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Ibrutinib versus temsirolimus in patients with relapsed or refractory mantle-cell lymphoma: an international, randomised, open-label, phase 3 study.

Dreyling, Martin (author)
Jurczak, Wojciech (author)
Jerkeman, Mats (author)
Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Bröstcancer-genetik,Institutionen för kliniska vetenskaper, Lund,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Breastcancer-genetics,Department of Clinical Sciences, Lund
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Silva, Rodrigo Santucci (author)
Rusconi, Chiara (author)
Trneny, Marek (author)
Offner, Fritz (author)
Caballero, Dolores (author)
Joao, Cristina (author)
Witzens-Harig, Mathias (author)
Hess, Georg (author)
Bence-Bruckler, Isabelle (author)
Cho, Seok-Goo (author)
Bothos, John (author)
Goldberg, Jenna D (author)
Enny, Christopher (author)
Traina, Shana (author)
Balasubramanian, Sriram (author)
Bandyopadhyay, Nibedita (author)
Sun, Steven (author)
Vermeulen, Jessica (author)
Rizo, Aleksandra (author)
Rule, Simon (author)
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 (creator_code:org_t)
2016
2016
English.
In: The Lancet. - 1474-547X. ; 387:10020, s. 770-778
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Mantle-cell lymphoma is an aggressive B-cell lymphoma with a poor prognosis. Both ibrutinib and temsirolimus have shown single-agent activity in patients with relapsed or refractory mantle-cell lymphoma. We undertook a phase 3 study to assess the efficacy and safety of ibrutinib versus temsirolimus in relapsed or refractory mantle-cell lymphoma.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Hematologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Hematology (hsv//eng)

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art (subject category)
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