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Patients without co...
Patients without comorbidities at the time of diagnosis of atrial fibrillation : causes of death during long-term follow-up compared to matched controls
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- Andersson, Tommy, 1970- (author)
- Örebro universitet,Institutionen för medicinska vetenskaper,Orebro Univ, Sch Med Sci, Dept Cardiol, Orebro, Sweden.
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- Magnuson, Anders (author)
- School of Medical Sciences, Örebro University, Örebro, Sweden,Clinical Epidemiology and Biostatistics,Orebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, Orebro, Sweden.
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- Bryngelsson, Ing-Liss (author)
- Department of Occupational and Environmental Medicine, School of Medical Sciences, Örebro University, Örebro, Sweden,Orebro Univ, Sch Med Sci, Dept Occupat & Environm Med, Orebro, Sweden.
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- Frøbert, Ole, 1964- (author)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology, Faculty of Health and Medical Sciences, Örebro University, Örebro, Sweden,Orebro Univ, Sch Med Sci, Dept Cardiol, Orebro, Sweden.
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- Henriksson, Karin M. (author)
- Uppsala universitet,Kardiovaskulär epidemiologi,AstraZeneca R&D, Molndal, Sweden.
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- Edvardsson, Nils, 1942 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
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- Poçi, Dritan, 1969- (author)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Cardiology, Örebro University Hospital, Örebro, Sweden,Orebro Univ, Sch Med Sci, Dept Cardiol, Orebro, Sweden.
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(creator_code:org_t)
- 2017-08-25
- 2017
- English.
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In: Clinical Cardiology. - : John Wiley & Sons. - 0160-9289 .- 1932-8737. ; 40:11, s. 1076-1082
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Abstract
Subject headings
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- BACKGROUND: Little is known about the long-term, cause-specific mortality risk in patients without comorbidities at the time of diagnosis of atrial fibrillation (AF).METHODS: From a nation-wide registry of patients hospitalized with incident AF between 1995 and 2008 we identified 9 519 patients with a first diagnosed AF and no comorbidities at the time of AF diagnosis. They were matched with 12 468 controls. The follow-up continued until December 2008. Causes of death were classified according to the ICD-10 codes.RESULTS: During follow-up, 11.1% of patients with AF and 8.3% of controls died. Cardiovascular diseases were the most common causes of death and the only diagnoses which showed significantly higher relative risk in patients with AF than controls (HR 2.0, 95% CI 1.8-2.3), and the relative risk was significantly higher in women than in men. Stroke was a more common cause among patients with AF, 13.1% versus 9.7% (HR 2.7, 95% CI 1.8-4.0), while cerebral hemorrhage was more common among controls, 4.7% versus 10.2% (HR 0.9, 95% CI 0.6-1.5). The time from AF diagnosis to death was 6.0 ± 3.1 years.CONCLUSIONS: In patients with incident AF and no known comorbidities at the time of AF diagnosis, only cardiovascular diseases were more often causes of death as compared to controls. Women carried a significantly higher relative risk than men.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- atrial fibrillation
- cause of death
- idiopathic
- morbidity
- mortality
Publication and Content Type
- ref (subject category)
- art (subject category)
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