Sökning: WFRF:(Cappellacci Loredana)
> Campagnaro Gustavo Daniel >
Trypanosoma brucei ...
Trypanosoma brucei Inhibition by Essential Oils from Medicinal and Aromatic Plants Traditionally Used in Cameroon (Azadirachta indica, Aframomum melegueta, Aframomum daniellii, Clausena anisata, Dichrostachys cinerea and Echinops giganteus)
-
Kamte, Stephane L. Ngahang (författare)
-
- Ranjbarian, Farahnaz (författare)
- Umeå universitet,Institutionen för medicinsk kemi och biofysik
-
Campagnaro, Gustavo Daniel (författare)
-
visa fler...
-
Nya, Prosper C. Biapa (författare)
-
Mbuntcha, Hélène (författare)
-
Woguem, Verlaine (författare)
-
Womeni, Hilaire Macaire (författare)
-
Tapondjou, Léon Azefack (författare)
-
Giordani, Cristiano (författare)
-
Barboni, Luciano (författare)
-
Benelli, Giovanni (författare)
-
Cappellacci, Loredana (författare)
-
- Hofer, Anders (författare)
- Umeå universitet,Institutionen för medicinsk kemi och biofysik
-
Petrelli, Riccardo (författare)
-
Maggi, Filippo (författare)
-
visa färre...
-
(creator_code:org_t)
- 2017-07-06
- 2017
- Engelska.
-
Ingår i: International Journal of Environmental Research and Public Health. - : MDPI AG. - 1661-7827 .- 1660-4601. ; 14:7
- Relaterad länk:
-
https://doi.org/10.3...
-
visa fler...
-
https://umu.diva-por... (primary) (Raw object)
-
https://www.mdpi.com...
-
https://urn.kb.se/re...
-
https://doi.org/10.3...
-
visa färre...
Abstract
Ämnesord
Stäng
- Essential oils are complex mixtures of volatile components produced by the plant secondary metabolism and consist mainly of monoterpenes and sesquiterpenes and, to a minor extent, of aromatic and aliphatic compounds. They are exploited in several fields such as perfumery, food, pharmaceutics, and cosmetics. Essential oils have long-standing uses in the treatment of infectious diseases and parasitosis in humans and animals. In this regard, their therapeutic potential against human African trypanosomiasis (HAT) has not been fully explored. In the present work, we have selected six medicinal and aromatic plants (Azadirachta indica, Aframomum melegueta, Aframomum daniellii, Clausena anisata, Dichrostachys cinerea, and Echinops giganteus) traditionally used in Cameroon to treat several disorders, including infections and parasitic diseases, and evaluated the activity of their essential oils against Trypanosma brucei TC221. Their selectivity was also determined with Balb/3T3 (mouse embryonic fibroblast cell line) cells as a reference. The results showed that the essential oils from A. indica, A. daniellii, and E. giganteus were the most active ones, with half maximal inhibitory concentration (IC50) values of 15.21, 7.65, and 10.50 mu g/mL, respectively. These essential oils were characterized by different chemical compounds such as sesquiterpene hydrocarbons, monoterpene hydrocarbons, and oxygenated sesquiterpenes. Some of their main components were assayed as well on T. brucei TC221, and their effects were linked to those of essential oils.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Nyckelord
- essential oils
- African trypanosomiases
- Trypanosma brucei
- Cameroon
- aromatic and medicinal plants
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Kamte, Stephane ...
-
Ranjbarian, Fara ...
-
Campagnaro, Gust ...
-
Nya, Prosper C. ...
-
Mbuntcha, Hélène
-
Woguem, Verlaine
-
visa fler...
-
Womeni, Hilaire ...
-
Tapondjou, Léon ...
-
Giordani, Cristi ...
-
Barboni, Luciano
-
Benelli, Giovann ...
-
Cappellacci, Lor ...
-
Hofer, Anders
-
Petrelli, Riccar ...
-
Maggi, Filippo
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Hälsovetenskap
-
och Folkhälsovetensk ...
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Hälsovetenskap
-
och Arbetsmedicin oc ...
- Artiklar i publikationen
-
International Jo ...
- Av lärosätet
-
Umeå universitet