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The socio-economic ...
The socio-economic burden of asthma is substantial in Europe
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Accordini, S (author)
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Corsico, A (author)
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Cerveri, I (author)
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Gislason, D (author)
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Gulsvik, A (author)
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- Janson, C (author)
- Uppsala universitet,Lungmedicin och allergologi
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Jarvis, D (author)
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Marcon, A (author)
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Pin, I (author)
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Vermeire, P (author)
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Almar, E (author)
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Bugiani, M (author)
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Cazzoletti, L (author)
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Duran-Tauleria, E (author)
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- Jõgi, R (author)
- Uppsala universitet,Lungmedicin och allergologi
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Marinoni, A (author)
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Martínez-Moratalla, J (author)
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Leynaert, B (author)
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de Marco, R (author)
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(creator_code:org_t)
- 2007-12-05
- 2008
- English.
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In: Allergy. European Journal of Allergy and Clinical Immunology. - : Wiley. - 0105-4538 .- 1398-9995. ; 63:1, s. 116-124
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- BACKGROUND: Few data are available on the asthma burden in the general population. We evaluated the level and the factors associated with the asthma burden in Europe. METHODS: In 1999-2002, 1152 adult asthmatics were identified in the European Community Respiratory Health Survey (ECRHS)-II and the socio-economic burden (reduced activity days and hospital services utilization in the past 12 months) was assessed. RESULTS: The asthmatics with a light burden (only a few reduced activity days) were 13.2% (95% CI: 11.4-15.3%), whereas those with a heavy burden (many reduced activity days and/or hospital services utilization) were 14.0% (95% CI: 12.1-16.1%). The burden was strongly associated with disease severity and a lower quality of life. Obese asthmatics had a significantly increased risk of a light [relative risk ratio (RRR) = 2.17; 95% CI: 1.18-4.00] or a heavy burden (RRR = 2.77; 95% CI: 1.52-5.05) compared with normal/underweight subjects. The asthmatics with frequent respiratory symptoms showed a threefold (RRR = 2.74; 95% CI: 1.63-4.61) and sixfold (RRR = 5.76; 95% CI: 3.25-10.20) increased risk of a light or a heavy burden compared with asymptomatic asthmatics, respectively. Moreover, the lower the forced expiratory volume in 1 s % predicted, the higher the risk of a heavy burden. The coexistence with chronic cough/phlegm only increased the risk of a heavy burden (RRR = 1.88; 95% CI: 1.16-3.06). An interaction was found between gender and IgE sensitization, with nonatopic asthmatic females showing the highest risk of a heavy burden (21.6%; 95% CI: 16.9-27.1%). CONCLUSIONS: The asthma burden is substantial in Europe. A heavy burden is more common in asthmatics with obesity, frequent respiratory symptoms, low lung function, chronic cough/phlegm and in nonatopic females.
Keyword
- asthma epidemiology
- burden of asthma
- burden
- determinants
- general population
- MEDICINE
- MEDICIN
Publication and Content Type
- vet (subject category)
- art (subject category)
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- By the author/editor
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Accordini, S
-
Corsico, A
-
Cerveri, I
-
Gislason, D
-
Gulsvik, A
-
Janson, C
-
show more...
-
Jarvis, D
-
Marcon, A
-
Pin, I
-
Vermeire, P
-
Almar, E
-
Bugiani, M
-
Cazzoletti, L
-
Duran-Tauleria, ...
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Jõgi, R
-
Marinoni, A
-
Martínez-Moratal ...
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Leynaert, B
-
de Marco, R
-
show less...
- Articles in the publication
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Allergy. Europea ...
- By the university
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Uppsala University