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Sökning: WFRF:(Daly Mark J) > Stockholms universitet

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Numrering	Referens	Omslagsbild	Hitta
1.	Ek, Weronica E, et al. (författare) Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts. 2015 Ingår i: Gut. - : BMJ. - 1468-3288 .- 0017-5749. ; 64, s. 1774-1782 Tidskriftsartikel (refereegranskat)abstract IBS shows genetic predisposition, but adequately powered gene-hunting efforts have been scarce so far. We sought to identify true IBS genetic risk factors by means of genome-wide association (GWA) and independent replication studies.
2.	Stockett, Mark H., et al. (författare) Photophysics of Isolated Rose Bengal Anions 2020 Ingår i: Journal of Physical Chemistry A. - : American Chemical Society (ACS). - 1089-5639 .- 1520-5215. ; 124:41, s. 8429-8438 Tidskriftsartikel (refereegranskat)abstract Dye molecules based on the xanthene moiety are widely used as fluorescent probes in bioimaging and technological applications due to their large absorption cross-section for visible light and high fluorescence quantum yield. These applications require a clear understanding of the dye's inherent photophysics and the effect of a condensed-phase environment. Here, the gas-phase photophysics of the rose bengal doubly deprotonated dianion [RB - 2H](2-), deprotonated monoanion [RB - H](-), and doubly deprotonated radical anion [RB - 2H](center dot-) is investigated using photodetachment, photoelectron, and dispersed fluorescence action spectroscopies, and tandem ion mobility spectrometry (IMS) coupled with laser excitation. For [RB - 2H](2-), photodetachment action spectroscopy reveals a clear band in the visible (450-580 nm) with vibronic structure. Electron affinity and repulsive Coulomb barrier (RCB) properties of the dianion are characterized using frequency-resolved photoelectron spectroscopy, revealing a decreased RCB compared with that of fluorescein dianions due to electron delocalization over halogen atoms. Monoanions [RB - H](-) and [RB 2H](center dot-) differ in nominal mass by 1 Da but are difficult to study individually using action spectroscopies that isolate target ions using low-resolution mass spectrometry. This work shows that the two monoanions are readily distinguished and probed using the IMSphoto-IMS and photo-IMS-photo-IMS strategies, providing distinct but overlapping photodissociation action spectra in the visible spectral range. Gas-phase fluorescence was not detected from photoexcited [RB - 2H](2-) due to rapid electron ejection. However, both [RB - H](-) and [RB - 2H](center dot-) show a weak fluorescence signal. The [RB - H](-) action spectra show a large Stokes shift of similar to 1700cm(-1), while the [RB - 2H](center dot-) action spectra show no appreciable Stokes shift. This difference is explained by considering geometries of the ground and fluorescing states.

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Resultat 1-2 av 2

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Typ av publikation: tidskriftsartikel (2)

Typ av innehåll: refereegranskat (2)

Författare/redaktör: Törnblom, Hans, 1966 (1); Simrén, Magnus, 1966 (1); Talley, Nicholas J. (1); Ohlsson, Bodil (1); Agréus, Lars (1); Lindberg, Greger (1); visa fler...; Andreasson, Anna (1); Burwinkel, Barbara (1); Pedersen, Nancy L (1); Ek, Weronica E (1); Karling, Pontus (1); Schmidt, Peter T. (1); Daly, Mark J. (1); Stockett, Mark H. (1); D'Amato, Mauro (1); Zucchelli, Marco (1); Bresso, Francesca (1); Kjaer, Christina (1); Bull, James N. (1); Assadi, Ghazaleh (1); Magnusson, Patrik (1); Holliday, Elizabeth ... (1); Walter, Susanna (1); Dlugosz, Aldona (1); Gazouli, Maria (1); Bellini, Massimo (1); Barbara, Giovanni (1); Camilleri, Michael (1); Ripke, Stephan (1); Bieske, Evan J. (1); Verlet, Jan R. R. (1); Li, Ling (1); Rivera, Natalia V (1); Papadaki, Evangelia (1); Surowy, Harald (1); Reznichenko, Anna (1); Niesler, Beate (1); Houghton, Lesley (1); Karamanolis, George (1); Rappold, Gudrun (1); Rafter, Joseph (1); Gambaccini, Dario (1); Marchi, Santino (1); Colucci, Rocchina (1); Blandizzi, Corrado (1); Barbaro, Raffaella (1); Boeckxstaens, Guy (1); Stanghellini, Vincen ... (1); Wouters, Mira M (1); Daly, Steven (1); visa färre...

Lärosäte: Stockholms universitet (2)Ta bort avgränsningen; Göteborgs universitet (1); Umeå universitet (1); Uppsala universitet (1); Linköpings universitet (1); Lunds universitet (1); visa fler...; Karolinska Institutet (1); visa färre...

Språk: Engelska (2)

Forskningsämne (UKÄ/SCB): Naturvetenskap (1); Medicin och hälsovetenskap (1)

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