| 1. |
- Sundström, Johan, Professor, 1971-, et al.
(författare)
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Risk factors for subarachnoid haemorrhage : a nationwide cohort of 950 000 adults
- 2019
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Ingår i: International Journal of Epidemiology. - : Oxford University Press. - 0300-5771 .- 1464-3685. ; 48:6, s. 2018-2025
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Subarachnoid haemorrhage (SAH) is a devastating disease, with high mortality rate and substantial disability among survivors. Its causes are poorly understood. We aimed to investigate risk factors for SAH using a novel nationwide cohort consortium.METHODS: We obtained individual participant data of 949 683 persons (330 334 women) between 25 and 90 years old, with no history of SAH at baseline, from 21 population-based cohorts. Outcomes were obtained from the Swedish Patient and Causes of Death Registries.RESULTS: During 13 704 959 person-years of follow-up, 2659 cases of first-ever fatal or non-fatal SAH occurred, with an age-standardized incidence rate of 9.0 [95% confidence interval (CI) (7.4-10.6)/100 000 person-years] in men and 13.8 [(11.4-16.2)/100 000 person-years] in women. The incidence rate increased exponentially with higher age. In multivariable-adjusted Poisson models, marked sex interactions for current smoking and body mass index (BMI) were observed. Current smoking conferred a rate ratio (RR) of 2.24 (95% CI 1.95-2.57) in women and 1.62 (1.47-1.79) in men. One standard deviation higher BMI was associated with an RR of 0.86 (0.81-0.92) in women and 1.02 (0.96-1.08) in men. Higher blood pressure and lower education level were also associated with higher risk of SAH.CONCLUSIONS: The risk of SAH is 45% higher in women than in men, with substantial sex differences in risk factor strengths. In particular, a markedly stronger adverse effect of smoking in women may motivate targeted public health initiatives.
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| 2. |
- Kehoe, Laura, et al.
(författare)
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Make EU trade with Brazil sustainable
- 2019
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 364:6438, s. 341-
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 3. |
- van der Valk, Ralf J P, et al.
(författare)
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A novel common variant in DCST2 is associated with length in early life and height in adulthood.
- 2015
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Ingår i: Human molecular genetics. - : Oxford University Press (OUP). - 1460-2083 .- 0964-6906. ; 24:4, s. 1155-68
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Tidskriftsartikel (refereegranskat)abstract
- Common genetic variants have been identified for adult height, but not much is known about the genetics of skeletal growth in early life. To identify common genetic variants that influence fetal skeletal growth, we meta-analyzed 22 genome-wide association studies (Stage 1; N = 28 459). We identified seven independent top single nucleotide polymorphisms (SNPs) (P < 1 × 10(-6)) for birth length, of which three were novel and four were in or near loci known to be associated with adult height (LCORL, PTCH1, GPR126 and HMGA2). The three novel SNPs were followed-up in nine replication studies (Stage 2; N = 11 995), with rs905938 in DC-STAMP domain containing 2 (DCST2) genome-wide significantly associated with birth length in a joint analysis (Stages 1 + 2; β = 0.046, SE = 0.008, P = 2.46 × 10(-8), explained variance = 0.05%). Rs905938 was also associated with infant length (N = 28 228; P = 5.54 × 10(-4)) and adult height (N = 127 513; P = 1.45 × 10(-5)). DCST2 is a DC-STAMP-like protein family member and DC-STAMP is an osteoclast cell-fusion regulator. Polygenic scores based on 180 SNPs previously associated with human adult stature explained 0.13% of variance in birth length. The same SNPs explained 2.95% of the variance of infant length. Of the 180 known adult height loci, 11 were genome-wide significantly associated with infant length (SF3B4, LCORL, SPAG17, C6orf173, PTCH1, GDF5, ZNFX1, HHIP, ACAN, HLA locus and HMGA2). This study highlights that common variation in DCST2 influences variation in early growth and adult height.
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| 4. |
- Bröms, Peter, et al.
(författare)
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Perspektiv på samarbetet i Barentsregionen
- 1994
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Ingår i: Internationella studier. - Stockholm : Utrikespolitiska institutet. - 0020-952X. ; :2
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Tidskriftsartikel (refereegranskat)
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| 5. |
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| 6. |
- Eklund, Johan, et al.
(författare)
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Inflicted Damages related to Folding Procedures on Digital Prints
- 2002
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- A study has been performed with the purpose of analysing different folding techniques and its functionality in a climate optimised for digital printing. Coated papers of stock weight 160g/m2, developed for digital printing, were printed in a multifunctional copier and folded with different methods. Results show that using a creasing rule substantially improves the quality. Other factors like folding method, time from print to fold, fibre orientation and toner layer presented small variations regarding fold print quality. The performed study is the start-up of a systematic mapping of folding of digital prints. Future studies will include a wide range of papers, printers, digital presses and finishing equipment. The tests will mainly be performed in a climate- controlled laboratory, giving possibility to analyse folding performance in different air humidity. The aim is to provide new knowledge about finishing of digital prints, as well as solutions to existing problems.
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| 7. |
- Eriksson, Erik, et al.
(författare)
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Integrated carbon analysis of forest management practices and wood substitution
- 2007
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Ingår i: Canadian Journal of Forest Research. - 0045-5067 .- 1208-6037. ; 37:3, s. 671-681
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Tidskriftsartikel (refereegranskat)abstract
- The complex fluxes between standing and harvested carbon stocks, and the linkage between harvested biomassand fossil fuel substitution, call for a holistic, system-wide analysis in a life-cycle perspective to evaluate the impacts offorest management and forest product use on carbon balances. We have analysed the net carbon emission under alternativeforest management strategies and product uses, considering the carbon fluxes and stocks associated with tree biomass,soils, and forest products. Simulations were made using three Norway spruce (Picea abies (L.) Karst.) forest managementregimes (traditional, intensive management, and intensive fertilization), three slash management practices (no removal, removal,and removal with stumps), two forest product uses (construction material and biofuel), and two reference fossilfuels (coal and natural gas). The greatest reduction of net carbon emission occurred when the forest was fertilized, slashand stumps were harvested, wood was used as construction material, and the reference fossil fuel was coal. The lowest reductionoccurred with a traditional forest management, forest residues retained on site, and harvested biomass was used asbiofuel to replace natural gas. Product use had the greatest impact on net carbon emission, whereas forest management regime,reference fossil fuel, and forest residue usage as biofuel were less significant.
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| 8. |
- Eriksson, Maria, 1976-, et al.
(författare)
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Achieving shared values : Learning from Disney
- 2007
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The need to achieve a strong corporate culture is one of the key questions within Total Quality Management (TQM). TQM is generally considered to be based on a number of core values; such as customer focus, decisions based on facts, process orientation, continuous improvement, everybody’s commitment and leadership, (Hellsten & Klefsjö, 2000). The core values should ideally be conformed to by all employees within a TQM organization, (ibid). Achieving these core values seems to be rewarding. Many companies that have succeeded in adapting their core values have received quality awards, e.g. Malcolm Baldridge National Quality Award and EFQM Excellence Model. These quality awards are based on values that are widely considered to be the building blocks of effective TQM implementation (Hendricks & Singhal, 1999). There are a lot of descriptions in literature about the importance of working with the ideas of TQM such as putting focus on the customer, establishing processes and also about educating the employees in using tools of improvement, but very little focus on discussing how shared values really are achieved. A common set of values within an organization is often referred to as the company or corporate culture. A strong culture implies that there is uniformity among the employees regarding, for example values (Pinder 1998). In our literature studies we came across two interesting strategies that combined together provide a tactic for working with shared values to attain a strong corporate culture. According to Chatman (1989) the best way is an integration of the strategies of selection and socialization. That implies both considering values at the selection when the organization chooses its members, by recruiting an individual with the right values and later on by maintaining or reinforcing values by socialization which can be done by training, orientation and other methods. As regards working with achieving TQM values we mostly encountered the use of socialization and feel that there is a need for broader thinking by putting greater emphasis on the selection process when recruiting new members into the organization. The purpose of this paper is to raise the discussion about how to achieve homogeneity of values, such as TQM values in order to be a successful organization. The presented theories are accompanied by an observation from the renowned Walt Disney World in Florida, providing an example of how they are working with the selection strategy.
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| 9. |
- Hergens, Maria-Pia, et al.
(författare)
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Use of Scandinavian Moist Smokeless Tobacco (Snus) and the Risk of Atrial Fibrillation
- 2014
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Ingår i: Epidemiology. - 1044-3983 .- 1531-5487. ; 25:6, s. 872-876
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Snus is a smokeless tobacco product, widely used among Swedish men and increasingly so elsewhere. There is debate as to whether snus is an acceptable "harm-reduction" tobacco product. Since snus use delivers a dose of nicotine equivalent to cigarettes, and has been implicated in cardiac arrhythmia because of associations with sudden cardiovascular death, a relation with atrial fibrillation is plausible and important to investigate.METHODS:: To assess the relation between use of snus and risk of atrial fibrillation, we carried out a pooled analysis of 7 prospective Swedish cohort studies. In total, 274,882 men, recruited between 1978 and 2004, were followed via the National Patient Register for atrial fibrillation. Primary analyses were restricted to 127,907 never-smokers. Relative risks were estimated using Cox proportional hazard regression.RESULTS:: The prevalence of snus use was 25% among never-smokers. During follow-up, 3,069 cases of atrial fibrillation were identified. The pooled relative risk of atrial fibrillation was 1.07 (95% confidence interval = 0.97-1.19) in current snus users, compared with nonusers.CONCLUSION:: Findings from this large national pooling project indicate that snus use is unlikely to confer any important increase in risk of atrial fibrillation.
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| 10. |
- Ingelsson, Pernilla, 1968-, et al.
(författare)
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Can selecting the right values help TQM implementation? : A case study about organisational homogeneity at the Walt Disney Company
- 2012
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Ingår i: Total Quality Management and Business Excellence. - : Routledge. - 1478-3363 .- 1478-3371. ; 23:1, s. 1-11
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Tidskriftsartikel (refereegranskat)abstract
- Total Quality Management, TQM, is often referred to as a value based management philosophy, built on a set of core values. These TQM values should ideally be conformed to by all employees in order to achieve a thriving organisation. A strong organisational culture with shared core values can therefore be identified as of importance for a successful TQM implementation. This paper discusses how organisations need to act in order to achieve shared values among co-workers. In the theory two strategies appear: to select people who appear to possess the desired values in the first place and to socialize employees once hired. When working with TQM, several examples of socialization can be found in described techniques and tools, however the selection strategy seems to be both unapplied and underestimated. In order to find empirical examples a case study was conducted at an organisation which is renowned for the way in which they work with values. A conclusion of this paper is that, as a complement to the use of socialization, a selection strategy is proposed in order to achieve shared values in order to facilitate TQM implementation.
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