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Neurologic Injury i...
Neurologic Injury in Patients Treated With Extracorporeal Membrane Oxygenation for Postcardiotomy Cardiogenic Shock
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- Toivonen, Fanni (författare)
- Lund University,Lunds universitet,Translationell infektionsmedicin,Forskargrupper vid Lunds universitet,Translational infection medicine,Lund University Research Groups,Skåne University Hospital
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- Biancari, Fausto (författare)
- University of Oulu,Helsinki University Central Hospital,University of Turku
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- Dalén, Magnus (författare)
- Karolinska Institutet
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- Dell'Aquila, Angelo M. (författare)
- University Hospital Münster
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- Jónsson, Kristján (författare)
- Sahlgrenska University Hospital
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- Fiore, Antonio (författare)
- Henri Mondor Hospital
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- Mariscalco, Giovanni (författare)
- Glenfield Hospital
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- El-Dean, Zein (författare)
- Glenfield Hospital
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- Gatti, Giuseppe (författare)
- University Hospital Of Trieste
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- Zipfel, Svante (författare)
- University Medical Center Hamburg-Eppendorf
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- Perrotti, Andrea (författare)
- University Hospital Jean Minjoz
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- Bounader, Karl (författare)
- Pontchaillou University Hospital
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- Alkhamees, Khalid (författare)
- Prince Sultan Cardiac Center
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- Loforte, Antonio (författare)
- University of Bologna,St. Orsola-Malpighi University Hospital
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- Lechiancole, Andrea (författare)
- University Hospital of Udine
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- Pol, Marek (författare)
- Institute for Clinical and Experimental Medicine (IKEM)
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- Spadaccio, Cristiano (författare)
- Golden Jubilee National Hospital
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- Pettinari, Matteo (författare)
- Hospital Oost-Limburg
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- De Keyzer, Dieter (författare)
- University Hospital of Düsseldorf
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- Welp, Henryk (författare)
- University Hospital of Düsseldorf
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- Lichtenberg, Artur (författare)
- University Hospital of Düsseldorf
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- Saeed, Diyar (författare)
- University Hospital of Düsseldorf
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- Ruggieri, Vito G. (författare)
- Robert Debré University Hospital
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- Ragnarsson, Sigurdur (författare)
- Lund University,Lunds universitet,Thoraxkirurgi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Thoracic Surgery,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
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(creator_code:org_t)
- Elsevier BV, 2021
- 2021
- Engelska 12 s.
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Ingår i: Journal of Cardiothoracic and Vascular Anesthesia. - : Elsevier BV. - 1053-0770 .- 1532-8422. ; 35:9, s. 2669-2680
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Objective: To investigate the frequency, predictors, and outcomes of neurologic injury in adults treated with postcardiotomy extracorporeal membrane oxygenation (PC-ECMO). Design: A retrospective multicenter registry study. Setting: Twenty-one European institutions where cardiac surgery is performed. Participants: A total of 781 adult patients who required PC-ECMO during 2010 to 2018 were divided into patients with neurologic injury (NI) and patients without neurologic injury (NNI). Measurements and Main Results: Baseline and operative data, in-hospital outcomes, and long-term survival were compared between the NI and the NNI groups. Predictors of neurologic injury were identified. A subgroup analysis according to the type of neurologic injury was performed. Overall, NI occurred in 19% of patients in the overall series, but the proportion of patients with NI ranged from 0% to 65% among the centers. Ischemic stroke occurred in 84 patients and hemorrhagic stroke in 47 patients. Emergency procedure was the sole independent predictor of NI. In-hospital mortality was higher in the NI group than in the NNI group (79% v 61%, p < 0.001). The one-year survival was lower in the NI group (17%) compared with the NNI group (37%). Long-term survival did not differ between patients with ischemic stroke and those with hemorrhagic stroke. Conclusion: Neurologic injury during PC-ECMO is common and associated with a dismal prognosis. There is considerable interinstitutional variation in the proportion of neurologic injury in PC-ECMO-treated adults. Well-known risk factors for stroke are not associated with neurologic injury in this setting.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- extracorporeal membrane oxygenation
- intracerebral hemorrhage
- ischemic stroke
- neurologic injury
- outcome
- postcardiotomy shock
- stroke
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- Av författaren/redakt...
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Toivonen, Fanni
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Biancari, Fausto
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Dalén, Magnus
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Dell'Aquila, Ang ...
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Jónsson, Kristjá ...
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Fiore, Antonio
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visa fler...
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Mariscalco, Giov ...
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El-Dean, Zein
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Gatti, Giuseppe
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Zipfel, Svante
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Perrotti, Andrea
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Bounader, Karl
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Alkhamees, Khali ...
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Loforte, Antonio
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Lechiancole, And ...
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Pol, Marek
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Spadaccio, Crist ...
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Pettinari, Matte ...
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De Keyzer, Diete ...
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Welp, Henryk
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Lichtenberg, Art ...
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Saeed, Diyar
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Ruggieri, Vito G ...
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Ragnarsson, Sigu ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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Journal of Cardi ...
- Av lärosätet
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Lunds universitet
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Karolinska Institutet