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1.	Andrews, Gregory, et al. (author) Mammalian evolution of human cis-regulatory elements and transcription factor binding sites 2023 In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 380:6643 Journal article (peer-reviewed)
2.	Christmas, Matthew, et al. (author) Evolutionary constraint and innovation across hundreds of placental mammals 2023 In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 380:6643 Journal article (peer-reviewed)abstract Zoonomia is the largest comparative genomics resource for mammals produced to date. By aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect fitness and alter disease risk. At least 332 million bases (similar to 10.7%) in the human genome are unusually conserved across species (evolutionarily constrained) relative to neutrally evolving repeats, and 4552 ultraconserved elements are nearly perfectly conserved. Of 101 million significantly constrained single bases, 80% are outside protein-coding exons and half have no functional annotations in the Encyclopedia of DNA Elements (ENCODE) resource. Changes in genes and regulatory elements are associated with exceptional mammalian traits, such as hibernation, that could inform therapeutic development. Earth's vast and imperiled biodiversity offers distinctive power for identifying genetic variants that affect genome function and organismal phenotypes.
3.	Foley, Nicole M., et al. (author) A genomic timescale for placental mammal evolution 2023 In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 380:6643 Journal article (peer-reviewed)
4.	Kaplow, Irene M., et al. (author) Relating enhancer genetic variation across mammals to complex phenotypes using machine learning 2023 In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 380:6643 Journal article (peer-reviewed)
5.	Keough, Kathleen C., et al. (author) Three-dimensional genome rewiring in loci with human accelerated regions 2023 In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 380:6643 Journal article (peer-reviewed)
6.	Kirilenko, Bogdan M., et al. (author) Integrating gene annotation with orthology inference at scale 2023 In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 380:6643 Journal article (peer-reviewed)
7.	Moon, Katherine L., et al. (author) Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs 2023 In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 380:6643 Journal article (peer-reviewed)
8.	Osmanski, Austin B., et al. (author) Insights into mammalian TE diversity through the curation of 248 genome assemblies 2023 In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 380:6643 Journal article (peer-reviewed)
9.	Paulat, Nicole S, et al. (author) Chiropterans Are a Hotspot for Horizontal Transfer of DNA Transposons in Mammalia 2023 In: Molecular biology and evolution. - : Oxford University Press. - 0737-4038 .- 1537-1719. ; 40:5 Journal article (peer-reviewed)
10.	Wilder, Aryn P., et al. (author) The contribution of historical processes to contemporary extinction risk in placental mammals 2023 In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 380:6643 Journal article (peer-reviewed)

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Type of publication: journal article (10)

Type of content: peer-reviewed (10)

Author/Editor: Lindblad-Toh, Kersti ... (10); Andrews, Gregory (10); Fan, Kaili (10); Karlsson, Elinor K. (10); Gazal, Steven (10); Armstrong, Joel C. (10); show more...; Bianchi, Matteo (10); Birren, Bruce W. (10); Breit, Ana M. (10); Damas, Joana (10); Diekhans, Mark (10); Dong, Michael X. (10); Fanter, Cornelia (10); Foley, Nicole M. (10); Gatesy, John (10); Genereux, Diane P. (10); Goodman, Linda (10); Grimshaw, Jenna (10); Hiller, Michael (10); Hindle, Allyson G. (10); Hubley, Robert M. (10); Di Palma, Federica (9); Bredemeyer, Kevin R. (9); Christmas, Matthew J ... (9); Clawson, Hiram (9); Eizirik, Eduardo (9); Forsberg-Nilsson, Ka ... (9); Garcia, Carlos J. (9); Halsey, Michaela K. (9); Harris, Andrew J. (9); Hickey, Glenn (9); Hughes, Graham M. (9); Meadows, Jennifer (9); Johnson, Jeremy (8); Kaplow, Irene M. (8); Juan, David (7); Keough, Kathleen C. (6); Kirilenko, Bogdan (6); Koepfli, Klaus-Peter (6); Kozyrev, Sergey V. (3); Ray, David A. (3); Korstian, Jennifer M ... (3); Kowalczyk, Amanda (3); Lawler, Alyssa J. (3); Shapiro, Beth (3); Swofford, Ross (2); Weng, Zhiping (2); Li, Xue (2); Marques-Bonet, Tomas (2); Pollard, Katherine S ... (2); show less...

University: Uppsala University (10); Karolinska Institutet (1)

Language: English (10)

Research subject (UKÄ/SCB): Natural sciences (10); Medical and Health Sciences (2)

Year: 2023 (10)

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