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Self-Reported Physi...
Self-Reported Physical Activity and Survival in Adults Treated With Hemodialysis : A DIET-HD Cohort Study
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- Bernier-Jean, Amelie (author)
- University of Sydney
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- Wong, Germaine (author)
- University of Sydney
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- Saglimbene, Valeria (author)
- University of Bari Aldo Moro,University of Sydney
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- Ruospo, Marinella (author)
- University of Bari Aldo Moro
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Palmer, Suetonia C. (author)
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- Natale, Patrizia (author)
- University of Sydney,University of Bari Aldo Moro
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- Garcia-Larsen, Vanessa (author)
- Johns Hopkins Bloomberg School of Public Health
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- Johnson, David W. (author)
- University of Queensland,Princess Alexandra Hospital
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- Tonelli, Marcello (author)
- Cumming School of Medicine
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- Hegbrant, Jörgen (author)
- Lund University,Lunds universitet,Njurmedicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Nephrology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
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Craig, Jonathan C. (author)
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- Teixeira-Pinto, Armando (author)
- University of Sydney
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- Strippoli, Giovanni F.M. (author)
- University of Bari Aldo Moro,University of Sydney
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(creator_code:org_t)
- Elsevier BV, 2021
- 2021
- English.
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In: Kidney International Reports. - : Elsevier BV. - 2468-0249. ; 6:12, s. 3014-3025
- Related links:
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http://dx.doi.org/10... (free)
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http://www.kireports...
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Abstract
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- Introduction: Regular physical activity is associated with longevity in adults receiving hemodialysis, but it is uncertain whether this association varies by causal pathways (cardiovascular and noncardiovascular). Methods: DIET-HD was a prospective, multinational study of adults undergoing hemodialysis across Europe and Argentina. We classified participants as physically inactive, occasionally active (irregularly to once a week), or frequently active (twice a week or more), using a self-reported questionnaire. Potential confounders were balanced across exposure groups using propensity scores. Weighted Cox proportional hazards models with double robust estimators evaluated the association between physical activity and all-cause, cardiovascular, and noncardiovascular mortality. Results: Of 8043 participants in DIET-HD, 6147 (76%) had information on physical activity. A total of 2940 (48%) were physically inactive, 1981 (32%) occasionally active, and 1226 (20%) frequently active. In a median follow-up of 3.8 years (19,677 person-years), 2337 (38%) deaths occurred, including 1050 (45%) from cardiovascular causes. After propensity score weighting, occasional physical activity was associated with lower all-cause (adjusted hazard ratio [aHR] = 0.80, 95% CI = 0.72–0.89), cardiovascular (aHR = 0.82, 95% CI = 0.70–0.96), and noncardiovascular (aHR = 0.81, 95% CI = 0.69–0.94) mortality compared with inactivity. Frequent physical activity was associated with lower all-cause (aHR = 0.82, 95% CI = 0.71–0.95) and cardiovascular (aHR = 0.77, 95% CI = 0.62–0.94) mortality, but not noncardiovascular mortality (aHR = 0.88, 95% CI = 0.72–1.08). A dose-dependent association of physical activity with cardiovascular death was observed (P trend = 0.01). Conclusion: Compared with self-reported physical inactivity, occasional and frequent physical activities were associated, dose dependently, with lower cardiovascular mortality in adults receiving hemodialysis.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- hemodialysis
- mortality
- physical activity
Publication and Content Type
- art (subject category)
- ref (subject category)
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Bernier-Jean, Am ...
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Wong, Germaine
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Saglimbene, Vale ...
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Ruospo, Marinell ...
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Palmer, Suetonia ...
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Natale, Patrizia
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Garcia-Larsen, V ...
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Johnson, David W ...
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Tonelli, Marcell ...
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Hegbrant, Jörgen
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Craig, Jonathan ...
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Teixeira-Pinto, ...
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Strippoli, Giova ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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Kidney Internati ...
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Lund University