Consensus guidelines for the diagnosis and management of patients with classic hairy cell leukemia

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Consensus guidelines for the diagnosis and management of patients with classic hairy cell leukemia

Grever, Michael R. (author): Ohio State University

Abdel-Wahab, Omar (author): Memorial Sloan-Kettering Cancer Center

Andritsos, Leslie A. (author): Ohio State University

Banerji, Versha (author): University of Manitoba

Barrientos, Jacqueline (author): Hofstra University

Blachly, James S. (author): Ohio State University

Call, Timothy G. (author): Mayo Clinic Minnesota

Catovsky, Daniel (author): Institute of Cancer Research London

Dearden, Claire (author): Royal Marsden Biomedical Research Centre

Demeter, Judit (author): Semmelweis University

Else, Monica (author): Institute of Cancer Research London

Forconi, Francesco (author): University Hospital Southampton

Gozzetti, Alessandro (author): Azienda Ospedaliera Universitaria Senese, Siena

Ho, Anthony D (author): Heidelberg University

Johnston, James B. (author): University of Manitoba

Jones, Jeffrey (author): Ohio State University

Juliusson, Gunnar (author): Lund University,Lunds universitet,Stamcellscentrum (SCC),Avdelningen för stamcellsforskning,Institutionen för laboratoriemedicin,Medicinska fakulteten,Stem Cell Center,Division of stem cell research,Department of Laboratory Medicine,Faculty of Medicine

Kraut, Eric (author): Ohio State University

Kreitman, Robert J. (author): National Cancer Institute, USA

Larratt, Loree (author): University of Alberta

Lauria, Francesco (author): Azienda Ospedaliera Universitaria Senese, Siena

Lozanski, Gerard (author): Ohio State University

Montserrat, Emili (author): University of Barcelona

Parikh, Sameer A. (author): Mayo Clinic Minnesota

Park, Jae-Hyun (author): Memorial Sloan-Kettering Cancer Center

Polliack, Aaron (author): Hadassah University Hospital

Quest, Graeme R. (author): University of Toronto

Rai, Kanti R. (author): Hofstra University

Ravandi, Farhad (author): University of Texas

Robak, Tadeusz (author): Medical University of Lodz

Saven, Alan (author): Scripps Clinic

Seymour, John F. (author): Peter MacCallum Cancer Centre

Tadmor, Tamar (author): Technion - Israel Institute of Technology

Tallman, Martin S. (author): Memorial Sloan-Kettering Cancer Center

Tam, Constantine (author): Peter MacCallum Cancer Centre

Tiacci, Enrico (author): University of Perugia

Troussard, Xavier (author): Centre Hospitalier Universitaire Côte de Nacre

Zent, Clive S. (author): University of Rochester

Zenz, Thorsten (author): German Cancer Research Centre

Zinzani, Pier-Luigi (author): University of Bologna

Falini, Brunangelo (author): University of Perugia

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(creator_code:org_t)

American Society of Hematology, 2017
2017
English 8 s.
In: Blood. - : American Society of Hematology. - 0006-4971 .- 1528-0020. ; 129:5, s. 553-560

Related links:: https://www.ncbi.nlm... (free); show more...; http://dx.doi.org/10...; https://ashpublicati...; https://lup.lub.lu.s...; https://doi.org/10.1...; show less...

Research review (peer-reviewed)

Abstract Subject headings

Hairy cell leukemia is an uncommon hematologic malignancy characterized by pancytopenia and marked susceptibility to infection. Tremendous progress in the management of patients with this disease has resulted in high response rates and improved survival, yet relapse and an appropriate approach to retreatment present continuing areas for research. The disease and its effective treatment are associated with immunosuppression. Because more patients are being treated with alternative programs, comparison of results will require general agreement on definitions of response, relapse, and methods of determining minimal residual disease. The development of internationally accepted, reproducible criteria is of paramount importance in evaluating and comparing clinical trials to provide optimal care. Despite the success achieved in managing these patients, continued participation in available clinical trials in the firstline and particularly in the relapse setting is highly recommended. The Hairy Cell Leukemia Foundation convened an international conference to provide common definitions and structure to guide current management. There is substantial opportunity for continued research in this disease. In addition to the importance of optimizing the prevention and management of the serious risk of infection, organized evaluations of minimal residual disease and treatment at relapse offer ample opportunities for clinical research. Finally, a scholarly evaluation of quality of life in the increasing number of survivors of this now manageable chronic illness merits further study. The development of consensus guidelines for this disease offers a framework for continued enhancement of the outcome for patients.

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By the author/editor: Grever, Michael ...; Abdel-Wahab, Oma ...; Andritsos, Lesli ...; Banerji, Versha; Barrientos, Jacq ...; Blachly, James S ...; show more...; Call, Timothy G.; Catovsky, Daniel; Dearden, Claire; Demeter, Judit; Else, Monica; Forconi, Frances ...; Gozzetti, Alessa ...; Ho, Anthony D; Johnston, James ...; Jones, Jeffrey; Juliusson, Gunna ...; Kraut, Eric; Kreitman, Robert ...; Larratt, Loree; Lauria, Francesc ...; Lozanski, Gerard; Montserrat, Emil ...; Parikh, Sameer A ...; Park, Jae-Hyun; Polliack, Aaron; Quest, Graeme R.; Rai, Kanti R.; Ravandi, Farhad; Robak, Tadeusz; Saven, Alan; Seymour, John F.; Tadmor, Tamar; Tallman, Martin ...; Tam, Constantine; Tiacci, Enrico; Troussard, Xavie ...; Zent, Clive S.; Zenz, Thorsten; Zinzani, Pier-Lu ...; Falini, Brunange ...; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Hematology

Articles in the publication: Blood

By the university: Lund University

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Consensus guidelines for the diagnosis and management of patients with classic hairy cell leukemia

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