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Sökning: WFRF:(Gullberg Mats) > Uppsala universitet

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Numrering	Referens	Omslagsbild	Hitta
1.	Dahl, Fredrik, et al. (författare) Circle-to-circle amplification for precise and sensitive DNA analysis. 2004 Ingår i: Proc Natl Acad Sci U S A. - 0027-8424. ; 101:13, s. 4548-53 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
2.	Dahl, Fredrik, et al. (författare) Multiplex amplification enabled by selective circularization of large sets of genomic DNA fragments 2005 Ingår i: Nucleic Acids Research. - 1362-4962. ; 33:8, s. e71- Tidskriftsartikel (refereegranskat)
3.	Landegren, Ulf, et al. (författare) Molecular tools for a molecular medicine : analyzing genes, transcripts and proteins using padlock and proximity probes 2004 Ingår i: Journal of Molecular Recognition. - : Wiley. - 0952-3499 .- 1099-1352. ; 17:3, s. 194-7 Tidskriftsartikel (refereegranskat)abstract Procedures and reagents are needed to specifically detect all the macromolecules that are being identified in the course of genome projects. We discuss how this challenge may be met using a set of ligation-based reagents termed padlock probes and proximity ligation probes. These probes include elements with affinity for specific nucleic acid and protein molecules, respectively, along with unique identifier DNA sequence elements that encode the identity of the recognized target molecules. The information content of DNA strands that form in the detection reactions are recorded after amplification, allowing the recognized target molecules to be identified. The procedures permit highly specific solution-phase or localized analyses of large sets of target molecules as required in future molecular analyses.
4.	Landegren, Ulf, et al. (författare) Padlock and proximity probes for in situ and array-based analyses : tools for the post genomic era 2003 Ingår i: Comparative and functional genomics. - : Hindawi Limited. - 1531-6912 .- 1532-6268. ; 4:5, s. 525-30 Tidskriftsartikel (refereegranskat)abstract Highly specific high-throughput assays will be required to take full advantage of the accumulating information about the macromolecular composition of cells and tissues, in order to characterize biological systems in health and disease. We discuss the general problem of detection specificity and present the approach our group has taken, involving the reformatting of analogue biological information to digital reporter segments of genetic information via a series of DNA ligation assays. The assays enable extensive, coordinated analyses of the numbers and locations of genes, transcripts and protein.
5.	Landegren, Ulf, et al. (författare) Prospects for in situ analyses of individual and complexes of DNA, RNA, and protein molecules with padlocks and proximity probes. 2004 Ingår i: Methods in Cell Biology, Cytometry. - : Elsevier. Bokkapitel (övrigt vetenskapligt/konstnärligt)
6.	McGinn, Steven, et al. (författare) New Technologies for DNA analysis-A review of the READNA Project. 2016 Ingår i: New Biotechnology. - : Elsevier BV. - 1876-4347 .- 1871-6784. Forskningsöversikt (refereegranskat)abstract The REvolutionary Approaches and Devices for Nucleic Acid analysis (READNA) project received funding from the European Commission for 4 1/2 years. The objectives of the project revolved around technological developments in nucleic acid analysis. The project partners have discovered, created and developed a huge body of insights into nucleic acid analysis, ranging from improvements and implementation of current technologies to the most promising sequencing technologies that constitute a 3(rd) and 4(th) generation of sequencing methods with nanopores and in situ sequencing, respectively.
7.	Nilsson, Mats, et al. (författare) Analyzing genes using closing and replicating circles. 2006 Ingår i: Trends Biotechnol. - 0167-7799. ; 24:2, s. 83-8 Tidskriftsartikel (refereegranskat)
8.	Nilsson, Mats, et al. (författare) Making ends meet in genetic analysis using padlock probes 2002 Ingår i: Hum. Mutat.. ; 19, s. 410- Tidskriftsartikel (refereegranskat)
9.	Nilsson, Mats, et al. (författare) Real-time monitoring of rolling-circle amplification using a modified molecular beacon design 2002 Ingår i: Nucleic Acids Research. - : Oxford University Press (OUP). - 0305-1048 .- 1362-4962. ; 30:14, s. e66- Tidskriftsartikel (refereegranskat)abstract We describe a method to monitor rolling-circle replication of circular oligonucleotides in dual-color and in real-time using molecular beacons. The method can be used to study the kinetics of the polymerization reaction and to amplify and quantify circularized oligonucleotide probes in a rolling-circle amplification (RCA) reaction. Modified molecular beacons were made of 2'-O-Me-RNA to prevent 3' exonucleolytic degradation by the polymerase used. Moreover, the complement of one of the stem sequences of the molecular beacon was included in the RCA products to avoid fluorescence quenching due to inter-molecular hybridization of neighboring molecular beacons hybridizing to the concatemeric polymerization product. The method allows highly accurate quantification of circularized DNA over a broad concentration range by relating the signal from the test DNA circle to an internal reference DNA circle reporting in a distinct fluorescence color.
10.	Orrling, Kristina, et al. (författare) An efficient method to perform milliliter-scale PCR utilizing highly controlled microwave thermocycling 2004 Ingår i: Chemical Communications. - : Royal Society of Chemistry (RSC). - 1359-7345 .- 1364-548X. ; 7:7, s. 790-791 Tidskriftsartikel (refereegranskat)abstract This communication describes the development of a controlled microwave methodology for rapid milliliter-scale PCR.

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Författare/redaktör: Landegren, Ulf (22); Nilsson, Mats (11); Jarvius, Jonas (11); Söderberg, Ola (11); Dahl, Fredrik (7); Schallmeiner, Edith (6); visa fler...; Jarvius, Malin (5); Kamali-Moghaddam, Ma ... (4); Stenberg, Johan (4); Larsson, Lars-Gunnar (3); Zieba, Agata (3); Claesson-Welsh, Lena (2); Östman, Arne (2); Betsholtz, Christer (2); Madsen, T (2); Olsson, Mats, 1960 (2); Tegelström, H (2); Bahram, Fuad (2); Danielson, Mats, 195 ... (1); Ekenberg, Love, 1962 ... (1); Nilsson, Peter (1); Larhed, Mats (1); Wittzell, H (1); Lehrach, Hans (1); Willcocks, Spike (1); Andersson, Dan I. (1); Tegenfeldt, Jonas (1); Fritzsche, Joachim, ... (1); Sjöblom, Tobias (1); Persson, Fredrik, 19 ... (1); Wählby, Carolina (1); Raap, Anton (1); Kaye, Jane (1); Andersson, Stefan (1); Pietras, Kristian (1); Andersson, Ann-Catri ... (1); Wester, Kenneth (1); Antson, Dan-Oscar (1); Ridderstråle, Karin (1); Birgisson, Helgi (1); Grannas, Karin (1); Westelius, Alf (1); Moens, Lotte (1); Cöster, Mathias, 196 ... (1); Göransson, Jenny (1); Mezger, Anja (1); Botling, Johan (1); Hydbring, Per (1); Kristensen, Anders (1); Tano, Eva (1); visa färre...

Lärosäte: Uppsala universitet (31)Ta bort avgränsningen; Göteborgs universitet (4); Stockholms universitet (3); Karolinska Institutet (2); Lunds universitet (1); Södertörns högskola (1); visa fler...; Chalmers tekniska högskola (1); visa färre...

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