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Träfflista för sökning "WFRF:(Hörnblad Andreas) ;pers:(Nord Christoffer)"

Sökning: WFRF:(Hörnblad Andreas) > Nord Christoffer

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1.
  • Cheddad, Abbas, et al. (författare)
  • Improving signal detection in emission optical projection tomography via single source multi-exposure image fusion
  • 2013
  • Ingår i: Optics Express. - : Optical Society of America. - 1094-4087. ; 21:14, s. 16584-16604
  • Tidskriftsartikel (refereegranskat)abstract
    • We demonstrate a technique to improve structural data obtained from Optical Projection Tomography (OPT) using Image Fusion (IF) and contrast normalization. This enables the visualization of molecular expression patterns in biological specimens with highly variable contrast values. In the approach, termed IF-OPT, different exposures are fused by assigning weighted contrasts to each. When applied to projection images from mouse organs and digital phantoms our results demonstrate the capability of IF-OPT to reveal high and low signal intensity details in challenging specimens. We further provide measurements to highlight the benefits of the new algorithm in comparison to other similar methods.
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2.
  • Hörnblad, Andreas, et al. (författare)
  • The pancreas
  • 2015. - 1
  • Ingår i: Kaufman's atlas of mouse development supplement. - : Elsevier. - 9780128000434 - 9780128009130 ; , s. 85-94
  • Bokkapitel (refereegranskat)abstract
    • This chapter aims to provide a three-dimensional description of the key morphological events, through which a discrete region of the early gut epithelium, as well as its associated mesenchyme, gives rise to the adult pancreas. Facilitated by recent advances in optical imaging techniques, including light sheet fluorescence microscopy and optical projection tomography, we present image series illustrating the growth of the organ and the formation of key morphological and anatomical features. Given the close developmental relationship between the pancreas-associated mesenchyme and the spleen anlage, and thus the potential for the developing spleen to influence pancreas morphogenesis, we include a brief section which covers the early development of this organ. Finally, we describe the spatial and quantitative distribution of the pancreatic endocrine (β-cell) component in adult mice and highlight lobular heterogeneities that may affect phenotypical evaluations of the gland.
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