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Träfflista för sökning "WFRF:(Hahn Tom) "

Sökning: WFRF:(Hahn Tom)

  • Resultat 1-9 av 9
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1.
  • Jung, Christian, et al. (författare)
  • A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention
  • 2019
  • Ingår i: Journal of critical care. - : W B SAUNDERS CO-ELSEVIER INC. - 0883-9441 .- 1557-8615. ; 52, s. 141-148
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: We aimed to evaluate differences in outcome between patients admitted to intensive care unit (ICU) after elective versus acute surgery in a multinational cohort of very old patients (80 years; VIP). Predictors of mortality, with special emphasis on frailty, were assessed.Methods: In total, 5063 VIPs were induded in this analysis, 922 were admitted after elective surgery or intervention, 4141 acutely, with 402 after acute surgery. Differences were calculated using Mann-Whitney-U test and Wilcoxon test. Univariate and multivariable logistic regression were used to assess associations with mortality.Results: Compared patients admitted after acute surgery, patients admitted after elective surgery suffered less often from frailty as defined as CFS (28% vs 46%; p < 0.001), evidenced lower SOFA scores (4 +/- 5 vs 7 +/- 7; p < 0.001). Presence of frailty (CFS >4) was associated with significantly increased mortality both in elective surgery patients (7% vs 12%; p = 0.01), in acute surgery (7% vs 12%; p = 0.02).Conclusions: VIPs admitted to ICU after elective surgery evidenced favorable outcome over patients after acute surgery even after correction for relevant confounders. Frailty might be used to guide clinicians in risk stratification in both patients admitted after elective and acute surgery. 
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2.
  • Sodergren, Erica, et al. (författare)
  • The genome of the sea urchin Strongylocentrotus purpuratus.
  • 2006
  • Ingår i: Science. - 1095-9203 .- 0036-8075. ; 314:5801, s. 941-52
  • Tidskriftsartikel (refereegranskat)abstract
    • We report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing strategy combined whole-genome shotgun and bacterial artificial chromosome (BAC) sequences. This use of BAC clones, aided by a pooling strategy, overcame difficulties associated with high heterozygosity of the genome. The genome encodes about 23,300 genes, including many previously thought to be vertebrate innovations or known only outside the deuterostomes. This echinoderm genome provides an evolutionary outgroup for the chordates and yields insights into the evolution of deuterostomes.
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3.
  • Aad, G., et al. (författare)
  • Measurements of the electron and muon inclusive cross-sections in proton-proton collisions at root s=7 TeV with the ATLAS detector
  • 2012
  • Ingår i: Physics Letters. Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier. - 0370-2693 .- 1873-2445. ; 707:5, s. 438-458
  • Tidskriftsartikel (refereegranskat)abstract
    • This Letter presents measurements of the differential cross-sections for inclusive electron and muon production in proton-proton collisions at a centre-of-mass energy of root s = 7 TeV, using data collected by the ATLAS detector at the LHC. The muon cross-section is measured as a function of p(T) in the range 4 < p(T) < 100 GeV and within pseudorapidity vertical bar eta vertical bar < 2.5. In addition the electron and muon cross-sections are measured in the range 7 < p(T) < 26 GeV and within vertical bar eta vertical bar < 2.0, excluding 1.37 < vertical bar eta vertical bar < 1.52. Integrated luminosities of 1.3 pb(-1) and 1.4 pb(-1) are used for the electron and muon measurements, respectively. After subtraction of the W/Z/gamma* contribution, the differential cross-sections are found to be in good agreement with theoretical predictions for heavy-flavour production obtained from Fixed Order NLO calculations with NLL high-p(T) resummation, and to be sensitive to the effects of NLL resummation. (C) 2011 CERN. Published by Elsevier B.V. All rights reserved.
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4.
  • Hahn, Thomas, et al. (författare)
  • Purposes and degrees of commodification : Economic instruments for biodiversity and ecosystem services need not rely on markets or monetary valuation
  • 2015
  • Ingår i: Ecosystem Services. - 2212-0416 .- 2212-0416. ; 16, s. 74-82
  • Tidskriftsartikel (refereegranskat)abstract
    • Commodification of nature refers to the expansion of market trade to previously non-marketed spheres. This is a contested issue both in the scientific literature and in policy deliberations. The aim of this paper is to analytically clarify and distinguish between different purposes and degrees of commodification and to focus attention to the safeguards: the detailed institutional design. We identify six degrees of commodification and find that all ecosystem services policies are associated with some degree of commodification but only the two highest degrees can properly be associated with neoliberalisation of nature. For example, most payments for ecosystem services (PES) are subsidy-like government compensations not based on monetary valuation of nature. Biodiversity offsets can be designed as market schemes or non-market regulations; the cost-effectiveness of markets cannot be assumed. To avoid the confusion around the concept 'market-based instrument' we suggest replacing it with 'economic instruments' since relying on the price signal is not the same thing as relying on the market. We provide a comprehensive framework emphasising the diversity in institutional design, valuation approaches and role of markets. This provides flexibility and options for policy integration of biodiversity and ecosystem services in different countries according to their political and cultural context.
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7.
  • Mairesse, Jérôme, et al. (författare)
  • Maternal stress alters endocrine function of the feto-placental unit in rats.
  • 2007
  • Ingår i: American journal of physiology. Endocrinology and metabolism. - 0193-1849. ; 292:6, s. E1526-33
  • Tidskriftsartikel (refereegranskat)abstract
    • Prenatal stress (PS) can cause early and long-term developmental effects resulting in part from altered maternal and/or fetal glucocorticoid exposure. The aim of the present study was to assess the impact of chronic restraint stress during late gestation on feto-placental unit physiology and function in embryonic (E) day 21 male rat fetuses. Chronic stress decreased body weight gain and food intake of the dams and increased their adrenal weight. In the placenta of PS rats, the expression of glucose transporter type 1 (GLUT1) was decreased, whereas GLUT3 and GLUT4 were slightly increased. Moreover, placental expression and activity of the glucocorticoid "barrier" enzyme 11beta-hydroxysteroid dehydrogenase type 2 was strongly reduced. At E21, PS fetuses exhibited decreased body, adrenal pancreas, and testis weights. These alterations were associated with reduced pancreatic beta-cell mass, plasma levels of glucose, growth hormone, and ACTH, whereas corticosterone, insulin, IGF-1, and CBG levels were unaffected. These data emphasize the impact of PS on both fetal growth and endocrine function as well as on placental physiology, suggesting that PS could program processes implied in adult biology and pathophysiology.
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8.
  • Singh, B., et al. (författare)
  • Feasibility studies of time-like proton electromagnetic form factors at P ¯ ANDA at FAIR
  • 2016
  • Ingår i: European Physical Journal A. - : Springer. - 1434-6001. ; 52:10
  • Tidskriftsartikel (refereegranskat)abstract
    • Simulation results for future measurements of electromagnetic proton form factors at P ¯ ANDA (FAIR) within the PandaRoot software framework are reported. The statistical precision with which the proton form factors can be determined is estimated. The signal channel p¯ p→ e+e- is studied on the basis of two different but consistent procedures. The suppression of the main background channel, i.e.p¯ p→ π+π-, is studied. Furthermore, the background versus signal efficiency, statistical and systematical uncertainties on the extracted proton form factors are evaluated using two different procedures. The results are consistent with those of a previous simulation study using an older, simplified framework. However, a slightly better precision is achieved in the PandaRoot study in a large range of momentum transfer, assuming the nominal beam conditions and detector performance.
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9.
  • Villaescusa-Navarro, Francisco, et al. (författare)
  • The Quijote Simulations
  • 2020
  • Ingår i: Astrophysical Journal Supplement Series. - 0067-0049 .- 1538-4365. ; 250:1
  • Tidskriftsartikel (refereegranskat)abstract
    • The QUIJOTE simulations are a set of 44,100 full N-body simulations spanning more than 7000 cosmological models in the {Omega(m), Omega(b), h, n(s), sigma(8), M-nu, w} hyperplane. At a single redshift, the simulations contain more than 8.5 trillion particles over a combined volume of 44,100 (h(-1) Gpc)(3); each simulation follows the evolution of 256(3), 512(3), or 1024(3) particles in a box of 1 h(-1) Gpc length. Billions of dark matter halos and cosmic voids have been identified in the simulations, whose runs required more than 35 million core hours. The QUIJOTE simulations have been designed for two main purposes: (1) to quantify the information content on cosmological observables and (2) to provide enough data to train machine-learning algorithms. In this paper, we describe the simulations and show a few of their applications. We also release the petabyte of data generated, comprising hundreds of thousands of simulation snapshots at multiple redshifts; halo and void catalogs; and millions of summary statistics, such as power spectra, bispectra, correlation functions, marked power spectra, and estimated probability density functions.
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  • Resultat 1-9 av 9

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