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Träfflista för sökning "WFRF:(Herlitz Agneta) ;pers:(Adolfsson Rolf)"

Search: WFRF:(Herlitz Agneta) > Adolfsson Rolf

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  • Nyberg, Lars, 1966-, et al. (author)
  • Biological and environmental predictors of heterogeneity in neurocognitive ageing : Evidence from Betula and other longitudinal studies
  • 2020
  • In: Ageing Research Reviews. - : Elsevier. - 1568-1637 .- 1872-9649. ; 64
  • Research review (peer-reviewed)abstract
    • Individual differences in cognitive performance increase with advancing age, reflecting marked cognitive changes in some individuals along with little or no change in others. Genetic and lifestyle factors are assumed to influence cognitive performance in aging by affecting the magnitude and extent of age-related brain changes (i.e., brain maintenance or atrophy), as well as the ability to recruit compensatory processes. The purpose of this review is to present findings from the Betula study and other longitudinal studies, with a focus on clarifying the role of key biological and environmental factors assumed to underlie individual differences in brain and cognitive aging. We discuss the vital importance of sampling, analytic methods, consideration of non-ignorable dropout, and related issues for valid conclusions on factors that influence healthy neurocognitive aging.
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2.
  • Yonker, Julie E, et al. (author)
  • Verified hormone therapy improves episodic memory performance in healthy postmenopausal women.
  • 2006
  • In: Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition. - Hove : Informa UK Limited. - 1382-5585 .- 1744-4128. ; 13:3-4, s. 291-307
  • Journal article (peer-reviewed)abstract
    • Studies of hormone therapy (HT) and cognition have yielded conflicting results. The aim of this observational study was to examine the effect of estradiol, via serum verified HT (estradiol, estriol, progesterone) and endogenous estradiol, on 108 healthy postmenopausal women's cognitive performance. The results demonstrated that the 43 HT-users performed at a significantly higher level than non-users on episodic memory tasks and on a verbal fluency task, whereas HT-users and non-users did not differ on tasks assessing semantic memory and spatial visualization. In addition, there was a positive relationship between serum estradiol level and episodic memory performance, indicating that postmenopausal HT is associated with enhanced episodic memory and verbal fluency, independent of age and education. These observational results suggest that HT use may be sufficient to exert small, yet positive effects on female sensitive cognitive tasks. Hormone therapy compliance and formulation is discussed as confounding factors in previous research.
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