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- Groenen, M. A., et al.
(författare)
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Analyses of pig genomes provide insight into porcine demography and evolution
- 2012
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 491:7424, s. 393-398
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Tidskriftsartikel (refereegranskat)abstract
- For 10,000 years pigs and humans have shared a close and complex relationship. From domestication to modern breeding practices, humans have shaped the genomes of domestic pigs. Here we present the assembly and analysis of the genome sequence of a female domestic Duroc pig (Sus scrofa) and a comparison with the genomes of wild and domestic pigs from Europe and Asia. Wild pigs emerged in South East Asia and subsequently spread across Eurasia. Our results reveal a deep phylogenetic split between European and Asian wild boars approximately 1 million years ago, and a selective sweep analysis indicates selection on genes involved in RNA processing and regulation. Genes associated with immune response and olfaction exhibit fast evolution. Pigs have the largest repertoire of functional olfactory receptor genes, reflecting the importance of smell in this scavenging animal. The pig genome sequence provides an important resource for further improvements of this important livestock species, and our identification of many putative disease-causing variants extends the potential of the pig as a biomedical model.
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| 2. |
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| 3. |
- Abbott, Benjamin W., et al.
(författare)
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Biomass offsets little or none of permafrost carbon release from soils, streams, and wildfire : an expert assessment
- 2016
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Ingår i: Environmental Research Letters. - : IOP Publishing. - 1748-9326. ; 11:3
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Tidskriftsartikel (refereegranskat)abstract
- As the permafrost region warms, its large organic carbon pool will be increasingly vulnerable to decomposition, combustion, and hydrologic export. Models predict that some portion of this release will be offset by increased production of Arctic and boreal biomass; however, the lack of robust estimates of net carbon balance increases the risk of further overshooting international emissions targets. Precise empirical or model-based assessments of the critical factors driving carbon balance are unlikely in the near future, so to address this gap, we present estimates from 98 permafrost-region experts of the response of biomass, wildfire, and hydrologic carbon flux to climate change. Results suggest that contrary to model projections, total permafrost-region biomass could decrease due to water stress and disturbance, factors that are not adequately incorporated in current models. Assessments indicate that end-of-the-century organic carbon release from Arctic rivers and collapsing coastlines could increase by 75% while carbon loss via burning could increase four-fold. Experts identified water balance, shifts in vegetation community, and permafrost degradation as the key sources of uncertainty in predicting future system response. In combination with previous findings, results suggest the permafrost region will become a carbon source to the atmosphere by 2100 regardless of warming scenario but that 65%-85% of permafrost carbon release can still be avoided if human emissions are actively reduced.
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| 4. |
- Xie, Z., et al.
(författare)
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Physiological responses to salinity change and diel-cycling hypoxia in gills of Hong Kong oyster Crassostrea hongkongensis
- 2023
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Ingår i: Aquaculture. - : Elsevier BV. - 0044-8486. ; 570
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Tidskriftsartikel (refereegranskat)abstract
- Global climate change is a frequent cause of salinity fluctuation in seawater, especially in aquaculture sites. Moreover, anthropologic activities often cause seawater eutrophication with the consequence that hypoxia ap-pears often during nighttime. The Hong Kong oyster Crassostrea hongkongensis, as a species that inhabits estuarine and coastal waters, is faced with such challenges. In this study, oyster physiological changes were considered to be closely related to hypoxia and salinity changes. Physiological indices were examined in Hong Kong oysters by employing six treatments to shed light into the effects of diel-cycling hypoxia (periodical hypoxia) and salinity change. Three salinities (10%o, low salinity; 25%o, normal salinity; and 35%o, high salinity) and two types of dissolved oxygen (normoxia, 6 mg/L throughout the day) and periodical hypoxic condition (6 mg/L at daytime for 12 h and 2 mg/L at nighttime for 12 h) were set. After 14-and 28-day exposures, gill tissues were sampled to detect changes in gill ATP production, mitochondrial membrane potential (MMP), mitochondrial reactive oxygen species production (ROS), and gill respiratory metabolic enzymes. Results indicated that periodical hypoxia and salinity change led to increased hexokinase (HK) and pyruvate kinase (PK) (p < 0.05). By contrast, they had no significant effect on mitochondrial number (MN). Adenosine-triphosphate (ATP) production only increased in the early exposure. In addition, low salinity with periodical hypoxia resulted in decreased MMP, lactate dehy-drogenase (LDH), and succinate dehydrogenase (SDH, p < 0.05). On the contrary, periodical hypoxia with high salinity led to increases in ATP and ROS and decreases in SDH, MMP, and LDH (p < 0.05). These results revealed that when diel-cycling hypoxia occurs with salinity change, the gill metabolism of Hong Kong oysters are gradually dominated by glycolysis while aerobic respiration decreases. Moreover, gill functions could be affected although energy accumulation exists during early exposure. Therefore, long-term exposure to periodical hypoxia with salinity change poses risk to the health and growth of Hong Kong oysters, impairing oyster aquaculture and coastal ecosystem health.
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