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Sökning: WFRF:(James Stefan) > Linnéuniversitetet

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1.
  • Hudson, Lawrence N, et al. (författare)
  • The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project
  • 2017
  • Ingår i: Ecology and Evolution. - : John Wiley & Sons. - 2045-7758. ; 7:1, s. 145-188
  • Tidskriftsartikel (refereegranskat)abstract
    • The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make freely available this 2016 release of the database, containing more than 3.2 million records sampled at over 26,000 locations and representing over 47,000 species. We outline how the database can help in answering a range of questions in ecology and conservation biology. To our knowledge, this is the largest and most geographically and taxonomically representative database of spatial comparisons of biodiversity that has been collated to date; it will be useful to researchers and international efforts wishing to model and understand the global status of biodiversity.
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2.
  • Christiansen, Evald H, et al. (författare)
  • Instantaneous Wave-free Ratio versus Fractional Flow Reserve to Guide PCI.
  • 2017
  • Ingår i: The New England journal of medicine. - : Massachussetts Medical Society. - 1533-4406 .- 0028-4793. ; 376:19, s. 1813-1823
  • Tidskriftsartikel (refereegranskat)abstract
    • The instantaneous wave-free ratio (iFR) is an index used to assess the severity of coronary-artery stenosis. The index has been tested against fractional flow reserve (FFR) in small trials, and the two measures have been found to have similar diagnostic accuracy. However, studies of clinical outcomes associated with the use of iFR are lacking. We aimed to evaluate whether iFR is noninferior to FFR with respect to the rate of subsequent major adverse cardiac events.We conducted a multicenter, randomized, controlled, open-label clinical trial using the Swedish Coronary Angiography and Angioplasty Registry for enrollment. A total of 2037 participants with stable angina or an acute coronary syndrome who had an indication for physiologically guided assessment of coronary-artery stenosis were randomly assigned to undergo revascularization guided by either iFR or FFR. The primary end point was the rate of a composite of death from any cause, nonfatal myocardial infarction, or unplanned revascularization within 12 months after the procedure.A primary end-point event occurred in 68 of 1012 patients (6.7%) in the iFR group and in 61 of 1007 (6.1%) in the FFR group (difference in event rates, 0.7 percentage points; 95% confidence interval [CI], -1.5 to 2.8; P=0.007 for noninferiority; hazard ratio, 1.12; 95% CI, 0.79 to 1.58; P=0.53); the upper limit of the 95% confidence interval for the difference in event rates fell within the prespecified noninferiority margin of 3.2 percentage points. The results were similar among major subgroups. The rates of myocardial infarction, target-lesion revascularization, restenosis, and stent thrombosis did not differ significantly between the two groups. A significantly higher proportion of patients in the FFR group than in the iFR group reported chest discomfort during the procedure.Among patients with stable angina or an acute coronary syndrome, an iFR-guided revascularization strategy was noninferior to an FFR-guided revascularization strategy with respect to the rate of major adverse cardiac events at 12 months. (Funded by Philips Volcano; iFR SWEDEHEART ClinicalTrials.gov number, NCT02166736 .).
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3.
  • Cohen, Scott A., et al. (författare)
  • Finding effective pathways to sustainable mobility : bridging the science-policy gap
  • 2016
  • Ingår i: Journal of Sustainable Tourism. - : Informa UK Limited. - 0966-9582 .- 1747-7646. ; 24:3 Special issue, s. 317-334
  • Tidskriftsartikel (refereegranskat)abstract
    • This overview paper examines three areas crucial to understanding why, despite clear scientific evidence for the growing environmental impacts of tourism transport, there is large-scale inertia in structural transitions and a lack of political will to enact meaningful sustainable mobility policies. These include the importance of addressing socio-technical factors, barriers posed by “technology myths” and the need to overcome “transport taboos” in policy-making. The paper seeks pathways to sustainable mobility by bridging the science–policy gap between academic research and researchers, and policy-makers and practitioners. It introduces key papers presented at the Freiburg 2014 workshop, covering the case for researcher engagement using advocacy and participatory approaches, the role of universities in creating their own social mobility policies, the power of social mechanisms encouraging long-haul travel, issues in consumer responsibility development, industry self-regulation and the operation of realpolitik decision-making and implementation inside formal and informal destination-based mobility partnerships. Overall, the paper argues that governments and the tourism and transport industries must take a more cautious approach to the technological optimism that fosters policy inertia, and that policy-makers must take a more open approach to implementing sustainable transport policies. A research agenda for desirable transport futures is suggested.
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4.
  • Cohen, Scott, et al. (författare)
  • The Rich Kids of Instagram : Luxury Travel, Transport Modes, and Desire
  • 2022
  • Ingår i: Journal of Travel Research. - : Sage Publications. - 0047-2875 .- 1552-6763. ; 61:7, s. 1479-1494
  • Tidskriftsartikel (refereegranskat)abstract
    • The Rich Kids of Instagram (RKOI) portray luxury lifestyles on social media. The potential roles of travel and transport within these online displays of affluence have not yet been examined. This paper's purpose is to analyse how transport modes and luxury travel are depicted and interrelated through RKOI images. Co-occurrence analyses were conducted using a data set of Instagram posts with RKOI as a hashtag (2012-2018) to visualize the roles of transport modes and luxury travel in RKOI image construction. The findings demonstrate that both energy-intensive transport modes and luxury travel, whether through air/watercraft or luxury cars, play a vital role in signaling RKOI's self-image on Instagram, with gendered differences. The article contributes an original conceptual model of how RKOI construct their image using transport modes and luxury travel. Implications for the social normalization of carbon-intensive transport choices, coupled with luxury destinations as a backdrop, are discussed.
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5.
  • Fröbert, Ole, 1964-, et al. (författare)
  • Long-term safety and efficacy of drug-eluting and bare metal stents in saphenous vein grafts
  • 2012
  • Ingår i: American Heart Journal. - : Elsevier. - 0002-8703 .- 1097-6744. ; 164:1, s. 87-93
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Long-term safety and efficacy data of drug-eluting stents (DESs) in saphenous vein grafts (SVGs) are lacking. This study sought to compare the clinical outcomes of DES versus bare metal stents (BMS) in SVGs.METHODS: We studied all stent implantations in SVGs in Sweden during 74 months between 2005 and 2011 registered in the Swedish Coronary Angiography and Angioplasty Registry. We evaluated outcome in patients who received DES compared with those who received BMS after adjustments for differences in clinical, vessel, and lesion characteristics.RESULTS: Mean follow-up time was 3 years and 4 months. A total of 4,576 stents, implanted at 3,063 procedures, were included in the analysis of which 2,499 stents (54.6 %) were BMS and 2,077 (45.4%) were DES. The outcome analysis was based on 190 stent thromboses, 898 restenoses, and 523 deaths. The incidence of stent thrombosis did not differ between groups. When adjusted for baseline characteristics, including a propensity score for receiving DES, the incidence of restenosis was significantly lower with DES as compared with BMS (risk ratio 0.83, 95% CI 0.70-0.97, P = .019). There was a difference in mortality in the crude analysis between DES and BMS, and after multivariable adjustment, this difference remained statistically significant (risk ratio 0.80, CI 0.65-0.99, P = .038).CONCLUSIONS: The use of DES compared with BMS in SVGs was associated with a significantly lower adjusted incidence of restenosis and death in this large, national, all-encompassing propensity adjusted observational study.
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6.
  • Gössling, Stefan, et al. (författare)
  • Can we fly less? : Evaluating the 'necessity' of air travel
  • 2019
  • Ingår i: Journal of Air Transport Management. - : Elsevier. - 0969-6997 .- 1873-2089. ; 81
  • Tidskriftsartikel (refereegranskat)abstract
    • Air travel is often justified as 'necessary' or 'unavoidable', in the sense that trips have purpose and value. Yet it is evident that people travel for reasons that may include forced and voluntary movement, with motives ranging from visiting friends and family, to leisure, or business. In light of the challenge to decarbonise transport, and the need to reduce greenhouse gas emissions, this paper discusses the perceived necessity of flight from individual and societal perspectives, while considering moral and economic viewpoints. It suggests that travel motives have different degrees of 'urgency', and that the 'necessity of flight' cannot be generalised. To empirically test this hypothesis in an exploratory survey, we used mixed methods to examine the perspectives of 29 international students at Lund University, Sweden on the perceived importance of their flights (n = 587) over a six-year period (2012-2017). Results show that the value associated with individual flights depends on flight motive, experience, life stage, or situational factors. Notably, almost half of the leisure flights made lack importance. Implications are discussed in the context of climate policy and the future development of the aviation system.
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7.
  • Gössling, Stefan, et al. (författare)
  • Desirable transport futures
  • 2018
  • Ingår i: Transportation Research Part D. - : Elsevier. - 1361-9209 .- 1879-2340. ; 61:Part: B, s. 301-309
  • Tidskriftsartikel (refereegranskat)abstract
    • This overview article for the special issue on 'Desirable Transport Futures' sets out with a brief introduction of the current development of the global transport system, suggesting that it remains unclear whether transport systems are heading towards desirable change. This desirability is defined as a reduction in the system's negative externalities, including accidents, congestion, pollutants and/or noise, while retaining its functionality. There is evidence that transport externalities continue to grow with an increasingly mobile and growing global population. Against this background, the article discusses what may constitute more desirable transport futures, as well as the barriers that have to be overcome to move towards such futures. The article concludes that transport governance will be essential to far-reaching change, and that greater focus has to be placed on individual and societal socio-psychological perspectives shaping mobility consumption. Nine papers contained in this special issue provide in-depth analyses of transport systems, as well as insight into how these may be changed in more systemic ways. A concluding research agenda is offered that outlines a number of innovative approaches researchers may pursue as part of further efforts to engender desirable transport futures.
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8.
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9.
  • Hambraeus, Kristina, et al. (författare)
  • SWEDEHEART annual report 2012
  • 2014
  • Ingår i: Scandinavian Cardiovascular Journal. - : Informa Healthcare. - 1401-7431 .- 1651-2006. ; 48:SUPPL. 63, s. 1-333
  • Tidskriftsartikel (refereegranskat)abstract
    • The Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART) supports continuous monitoring and improvement of care for coronary artery disease, catheter-based and surgical coronary interventions, secondary prevention as well as catheter based and surgical valve intervention, by providing extensive data on base-line, diagnostic, procedural and outcome variables. Design. This national quality registry collects information from all Swedish hospitals treating patients with acute coronary artery disease and all patients undergoing coronary angiography, catheter-based interventions or heart surgery. Combination with other national mandatory official registries enables complete follow-up of all individuals regarding myocardial infarction, new interventional procedures, death and all-cause hospitalizations. The registry is governed by an independent steering committee and funded by the Swedish National Health care provider. The software is developed by Uppsala Clinical Research Center. Results. The SWEDEHEART Quality Index reflects overall quality of care for coronary artery disease including secondary prevention. In comparison with 2011, an improvement of the index occurred in 2012 overall. There was however, still a wide range in performance between individual centers, emphasizing the need for continuous monitoring of quality of care at a national as well as on a center level. © 2014 Informa Healthcare.
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10.
  • Harnek, Jan, et al. (författare)
  • The 2011 outcome from the Swedish Health Care Registry on Heart Disease (SWEDEHEART)
  • 2013
  • Ingår i: Scandinavian Cardiovascular Journal. - : Informa UK Limited. - 1401-7431 .- 1651-2006. ; 47, s. 1-10
  • Tidskriftsartikel (refereegranskat)abstract
    • Objectives. The Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART) collects data to support the improvement of care for heart disease. Design. SWEDEHEART collects on-line data from consecutive patients treated at any coronary care unit n = (74), followed for secondary prevention, undergoing any coronary angiography, percutaneous coronary intervention, percutaneous valve or cardiac surgery. The registry is governed by an independent steering committee, the software is developed by Uppsala Clinical Research Center and it is funded by The Swedish national health care provider independent of industry support. Approximately 80,000 patients per year enter the database which consists of more than 3 million patients. Results. Base-line, procedural, complications and discharge data consists of several hundred variables. The data quality is secured by monitoring. Outcomes are validated by linkage to other registries such as the National Cause of Death Register, the National Patient Registry, and the National Registry of Drug prescriptions. Thanks to the unique social security number provided to all citizens follow-up is complete. The 2011 outcomes with special emphasis on patients more than 80 years of age are presented. Conclusion. SWEDEHEART is a unique complete national registry for heart disease.
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