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Enumeration	Reference	Cover	Find
1.	Berman, Sara E, et al. (author) Intracranial Arterial 4D-Flow is Associated with Metrics of Brain Health and Alzheimer's Disease. 2015 In: Alzheimer's & dementia (Amsterdam, Netherlands). - : Wiley. - 2352-8729. ; 1:4, s. 420-428 Journal article (peer-reviewed)abstract While cerebrovascular disease has long been known to co-occur with Alzheimer's disease (AD), recent studies suggest an etiologic contribution to AD pathogenesis. We used 4D-Flow magnetic resonance imaging (MRI) to evaluate blood flow and pulsatility indices in the Circle of Willis. We hypothesized decreased mean blood flow and increased pulsatility, metrics indicative of poor vascular health, would be associated with cerebral atrophy and an AD cerebrospinal fluid (CSF) profile.
2.	Melah, Kelsey E, et al. (author) Cerebrospinal Fluid Markers of Alzheimer's Disease Pathology and Microglial Activation are Associated with Altered White Matter Microstructure in Asymptomatic Adults at Risk for Alzheimer's Disease. 2016 In: Journal of Alzheimer's disease : JAD. - 1875-8908. ; 50:3, s. 873-886 Journal article (peer-reviewed)abstract The immune response in Alzheimer's disease (AD) involves activation of microglia which may remove amyloid-β (Aβ). However, overproduction of inflammatory compounds may exacerbate neural damage in AD. AD pathology accumulates years before diagnosis, yet the extent to which neuroinflammation is involved in the earliest disease stages is unknown.

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Author/Editor: Blennow, Kaj, 1958 (2); Zetterberg, Henrik, ... (2); Rowley, Howard A (2); Carlsson, Cynthia M (2); Asthana, Sanjay (2)Undo refine; Bendlin, Barbara B (2); show more...; Johnson, Sterling C (2); Bratzke, Lisa C (2); Okonkwo, Ozioma C (1); Alexander, Andrew L (1); Sager, Mark A (1); Berman, Sara E (1); Clark, Lindsay R (1); Rivera-Rivera, Leona ... (1); Racine, Annie M (1); Turski, Patrick (1); Wieben, Oliver (1); Keevil, Jon G (1); Gleason, Carey E (1); Adluru, Nagesh (1); Melah, Kelsey E (1); Lu, Sharon Yuan-Fu (1); Hoscheidt, Siobhan M (1); Destiche, Daniel J (1); Dowling, N Maritza (1); show less...

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