Adjusted estimate of the prevalence of hepatitis delta virus in 25 countries and territories

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Adjusted estimate of the prevalence of hepatitis delta virus in 25 countries and territories

Razavi-Shearer, Devin M. (author)

Buti, Maria (author)

Tacke, Frank (author)

Terrault, Norah A. (author)

Zeuzem, Stefan (author)

Abbas, Zaigham (author)

Aghemo, Alessio (author)

Akarca, Ulus S. (author)

Al Masri, Nasser M. (author)

Alalwan, Abduljaleel M. (author)

Blome, Marianne Alanko (author)

Aleman, Soo (author)

Alghamdi, Abdullah S. (author)

Alghamdi, Mohammed (author)

Alghamdi, Saad (author)

Al-Hamoudi, Waleed K. (author)

Ali, Ela (author)

Aljumah, Abdulrahman A. (author)

Altraif, Ibrahim H. (author)

Amarsanaa, Jazag (author)

Asselah, Tarik (author)

Baatarkhuu, Oidov (author)

Babameto, Adriana (author)

Ben-Ari, Ziv (author)

Berg, Thomas (author)

Biondi, Mia J. (author)

Braga, Wornei S. M. (author)

Brandao-Mello, Carlos E. (author)

Jr, Robert S. Brown (author)

Brunetto, Maurizia R. (author)

Cabezas, Joaquin (author)

Cardoso, Mariana (author)

Chan, Henry Lik Yuen (author)

Cheinquer, Hugo (author)

Chen, Chien-Jen (author)

Chen, Pei-Jer (author)

Chien, Cheng-Hung (author)

Child, Hailey (author)

Chuang, Wan-Long (author)

Garza, Laura E. Cisneros (author)

Coco, Barbara (author)

Coffin, Carla S. (author)

Coppola, Nicola (author)

Cornberg, Markus (author)

Craxi, Antonio (author)

Crespo, Javier (author)

Cuko, Liri (author)

De Ledinghen, Victor (author)

Duberg, Ann-Sofi (author)

Etzion, Ohad (author)

Ferraz, Maria Lucia G. (author)

Ferreira, Paulo R. A. (author)

Forns, Xavier (author)

Foster, Graham R. (author)

Fung, James (author)

Gaeta, Giovanni B. (author)

Garcia-Samaniego, Javier (author)

Genov, Jordan (author)

Gheorghe, Liliana S. (author)

Gholam, Pierre M. (author)

Gish, Robert G. (author)

Glenn, Jeffrey (author)

Goldis, Adrian (author)

Hamid, Saeed S. (author)

Hercun, Julian (author)

Hsu, Yao-Chun (author)

Hu, Ching-Chih (author)

Huang, Jee-Fu (author)

Idilman, Ramazan (author)

Jafri, Wasim S. M. (author)

Janjua, Naveed (author)

Jelev, Deian (author)

Jerkeman, Anna (author)

Jia, Jidong (author)

Kaberg, Martin (author)

Kaita, Kelly D. E. (author)

Kao, Jia-Horng (author)

Khan, Aamir G. (author)

Kim, Do Young (author)

Kondili, Loreta A. (author)

Lagging, Martin, 1965 (author): Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine

Lampertico, Pietro (author)

Lazaro, Pablo (author)

Lazarus, Jeffrey (author)

Lee, Mei-Hsuan (author)

Lim, Young-Suk (author)

Lobato, Cirley M. O. (author)

Macedo, Guilherme (author)

Marinho, Rui T. (author)

Marotta, Paul J. (author)

Martins, Alexanda (author)

Mendes-Correa, Maria Cassia (author)

Mendez-Sanchez, Nahum (author)

Navas, Maria-Cristina (author)

Ning, Qing (author)

Ormeci, Necati (author)

Orrego, Mauricio (author)

Osiowy, Carla (author)

Pan, Calvin Q. (author)

Pessoa, Mario G. (author)

Piracha, Zahra Z. (author)

Pop, Cora (author)

Ramos, Jose A. Presa (author)

Qureshi, Huma (author)

Raimondo, Giovanni (author)

Ramji, Alnoor (author)

Razavi-Shearer, Kathryn (author)

Ribeiro, Sofia (author)

Rios-Hincapie, Cielo Y. (author)

Rodriguez, Manuel (author)

Rosenberg, William M. C. (author)

Roulot, Dominique (author)

Ryder, Stephen D. (author)

Saeed, Umar (author)

Safadi, Rifaat (author)

Sanai, Faisal M. (author)

Sanchez-Avila, Juan F. (author)

Santantonio, Teresa A. (author)

Sarrazin, Christoph (author)

Seto, Wai-Kay (author)

Shouval, Daniel (author)

Simonova, Marieta Y. (author)

Tanaka, Junko (author)

Tergast, Tammo L. (author)

Tsendsuren, Oyunsuren (author)

Valente, Cristina (author)

Villalobos-Salcedo, Juan Miguel (author)

Voeller, Alexis S. (author)

Waheed, Yasir (author)

Wong, Grace L-H (author)

Wong, Vincent W-S (author)

Wu, Jaw-Ching (author)

Yang, Hwai- (author)

Yip, Terry C-F (author)

Yu, Ming-Lung (author)

Yuen, Man-Fung (author)

Yurdaydin, Cihan (author)

Zuckerman, Eli (author)

Razavi, Homie A. (author)

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(creator_code:org_t)

2024
2024
English.
In: JOURNAL OF HEPATOLOGY. - 0168-8278 .- 1600-0641. ; 80:2, s. 232-242

Related links:: https://gup.ub.gu.se...; show more...; https://doi.org/10.1...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

Background & Aims: Hepatitis delta virus (HDV) is a satellite RNA virus that requires the hepatitis B virus (HBV) for assembly and propagation. Individuals infected with HDV progress to advanced liver disease faster than HBV-monoinfected individuals. Recent studies have estimated the global prevalence of anti-HDV antibodies among the HBV-infected population to be 5-15%. This study aimed to better understand HDV prevalence at the population level in 25 countries/territories. Methods: We conducted a literature review to determine the prevalence of anti-HDV and HDV RNA in hepatitis B surface antigen (HBsAg)-positive individuals in 25 countries/territories. Virtual meetings were held with experts from each setting to discuss the findings and collect unpublished data. Data were weighted for patient segments and regional heterogeneity to estimate the prevalence in the HBV-infected population. The findings were then combined with The Polaris Observatory HBV data to estimate the anti-HDV and HDV RNA prevalence in each country/territory at the population level. Results: After adjusting for geographical distribution, disease stage and special populations, the anti-HDV prevalence among the HBsAg+ population changed from the literature estimate in 19 countries. The highest anti-HDV prevalence was 60.1% in Mongolia. Once adjusted for the size of the HBsAg+ population and HDV RNA positivity rate, China had the highest absolute number of HDV RNA+ cases. Conclusions: We found substantially lower HDV prevalence than previously reported, as prior meta-analyses primarily focused on studies conducted in groups/regions that have a higher probability of HBV infection: tertiary care centers, specific risk groups or geographical regions. There is large uncertainty in HDV prevalence estimates. The implementation of reflex testing would improve estimates, while also allowing earlier linkage to care for HDV RNA+ individuals. The logistical and economic burden of reflex testing on the health system would be limited, as only HBsAg+ cases would be screened.

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By the author/editor: Razavi-Shearer, ...; Buti, Maria; Tacke, Frank; Terrault, Norah ...; Zeuzem, Stefan; Abbas, Zaigham; show more...; Aghemo, Alessio; Akarca, Ulus S.; Al Masri, Nasser ...; Alalwan, Abdulja ...; Blome, Marianne ...; Aleman, Soo; Alghamdi, Abdull ...; Alghamdi, Mohamm ...; Alghamdi, Saad; Al-Hamoudi, Wale ...; Ali, Ela; Aljumah, Abdulra ...; Altraif, Ibrahim ...; Amarsanaa, Jazag; Asselah, Tarik; Baatarkhuu, Oido ...; Babameto, Adrian ...; Ben-Ari, Ziv; Berg, Thomas; Biondi, Mia J.; Braga, Wornei S. ...; Brandao-Mello, C ...; Jr, Robert S. Br ...; Brunetto, Mauriz ...; Cabezas, Joaquin; Cardoso, Mariana; Chan, Henry Lik ...; Cheinquer, Hugo; Chen, Chien-Jen; Chen, Pei-Jer; Chien, Cheng-Hun ...; Child, Hailey; Chuang, Wan-Long; Garza, Laura E. ...; Coco, Barbara; Coffin, Carla S.; Coppola, Nicola; Cornberg, Markus; Craxi, Antonio; Crespo, Javier; Cuko, Liri; De Ledinghen, Vi ...; Duberg, Ann-Sofi; Etzion, Ohad; Ferraz, Maria Lu ...; Ferreira, Paulo ...; Forns, Xavier; Foster, Graham R ...; Fung, James; Gaeta, Giovanni ...; Garcia-Samaniego ...; Genov, Jordan; Gheorghe, Lilian ...; Gholam, Pierre M ...; Gish, Robert G.; Glenn, Jeffrey; Goldis, Adrian; Hamid, Saeed S.; Hercun, Julian; Hsu, Yao-Chun; Hu, Ching-Chih; Huang, Jee-Fu; Idilman, Ramazan; Jafri, Wasim S. ...; Janjua, Naveed; Jelev, Deian; Jerkeman, Anna; Jia, Jidong; Kaberg, Martin; Kaita, Kelly D. ...; Kao, Jia-Horng; Khan, Aamir G.; Kim, Do Young; Kondili, Loreta ...; Lagging, Martin, ...; Lampertico, Piet ...; Lazaro, Pablo; Lazarus, Jeffrey; Lee, Mei-Hsuan; Lim, Young-Suk; Lobato, Cirley M ...; Macedo, Guilherm ...; Marinho, Rui T.; Marotta, Paul J.; Martins, Alexand ...; Mendes-Correa, M ...; Mendez-Sanchez, ...; Navas, Maria-Cri ...; Ning, Qing; Ormeci, Necati; Orrego, Mauricio; Osiowy, Carla; Pan, Calvin Q.; Pessoa, Mario G.; Piracha, Zahra Z ...; Pop, Cora; Ramos, Jose A. P ...; Qureshi, Huma; Raimondo, Giovan ...; Ramji, Alnoor; Razavi-Shearer, ...; Ribeiro, Sofia; Rios-Hincapie, C ...; Rodriguez, Manue ...; Rosenberg, Willi ...; Roulot, Dominiqu ...; Ryder, Stephen D ...; Saeed, Umar; Safadi, Rifaat; Sanai, Faisal M.; Sanchez-Avila, J ...; Santantonio, Ter ...; Sarrazin, Christ ...; Seto, Wai-Kay; Shouval, Daniel; Simonova, Mariet ...; Tanaka, Junko; Tergast, Tammo L ...; Tsendsuren, Oyun ...; Valente, Cristin ...; Villalobos-Salce ...; Voeller, Alexis ...; Waheed, Yasir; Wong, Grace L-H; Wong, Vincent W- ...; Wu, Jaw-Ching; Yang, Hwai-; Yip, Terry C-F; Yu, Ming-Lung; Yuen, Man-Fung; Yurdaydin, Cihan; Zuckerman, Eli; Razavi, Homie A.; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Gastroenterology ...

Articles in the publication: JOURNAL OF HEPAT ...

By the university: University of Gothenburg

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Adjusted estimate of the prevalence of hepatitis delta virus in 25 countries and territories

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