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- Kalkal, Ashish, et al.
(författare)
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Recent advances in 3D printing technologies for wearable (bio)sensors
- 2021
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Ingår i: Additive Manufacturing. - : ELSEVIER. - 2214-8604 .- 2214-7810. ; 46
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Forskningsöversikt (refereegranskat)abstract
- Wearable (bio)sensors driven through emerging three-dimensional (3D) printing technologies are currently considered the next-generation tools for various healthcare applications due to their exciting characteristics such as high stretchability, super flexibility, low cost, ultra-thinness, and lightweight. In this context, 3D printing, an emerging advanced additive manufacturing technology has revolutionized the concept of free form construction and end-user customization owing to its multifarious peculiarities that involve ease of operation, on-demand and rapid fabrication, precise and controlled deposition, as well as versatility with various soft functional materials. The customized functional structures with controllable geometry and design can be autonomously printed on the desired surfaces using the 3D printing technologies excluding the prerequisite amenities of microfabrication technologies. To accomplish this, both academics and industry experts have worked persistently to fabricate smaller, faster, and more efficient wearable devices using readily available 3D printing technologies. The contribution of 3D printing technologies in developing novel 3D structures for wearable applications using printable soft and functional materials is highlighted in this article. Moreover, the process of 3D printing along with major techniques, namely vat photopolymerization, material jetting, and material extrusion are summarized. Besides this, a number of 3D printed (bio)sensing platforms such as glucose sensors, lactate sensors, sweat sensors, strain sensors, tactile sensors, wearable oximeters, smart bandages, artificial skin, tattoo sensors, electroencephalography (EEG), electrocardiography (ECG) sensors, etc., are discussed in terms of design specifications and fabrication strategies of devices obtained via 3D printing techniques.
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2. |
- Rai, Nilesh, et al.
(författare)
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Fungal Endophytes : an Accessible Source of Bioactive Compounds with Potential Anticancer Activity
- 2022
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Ingår i: Applied Biochemistry and Biotechnology. - : Springer. - 0273-2289 .- 1559-0291. ; 194, s. 3296-3319
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Forskningsöversikt (refereegranskat)abstract
- Endophytes either be bacteria, fungi, or actinomycetes colonize inside the tissue of host plants without showing any immediate negative effects on them. Among numerous natural alternative sources, fungal endophytes produce a wide range of structurally diverse bioactive metabolites including anticancer compounds. Considering the production of bioactive compounds in low quantity, genetic and physicochemical modification of the fungal endophytes is performed for the enhanced production of bioactive compounds. Presently, for the treatment of cancer, chemotherapy is majorly used, but the side effects of chemotherapy are of prime concern in clinical practices. Also, the drug-resistant properties of carcinoma cells, lack of cancer cells-specific medicine, and the side effects of drugs are the biggest obstacles in cancer treatment. The interminable requirement of potential drugs has encouraged researchers to seek alternatives to find novel bioactive compounds, and fungal endophytes seem to be a probable target for the discovery of anticancer drugs. The present review focuses a comprehensive literature on the major fungal endophyte-derived bioactive compounds which are presently been used for the management of cancer, biotic factors influencing the production of bioactive compounds and about the challenges in the field of fungal endophyte research.
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- Patil, Sayali Ashok, et al.
(författare)
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2D Zinc Oxide - Synthesis, Methodologies, Reaction Mechanism, and Applications
- 2023
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Ingår i: Small. - : WILEY-V C H VERLAG GMBH. - 1613-6810 .- 1613-6829. ; 19:14
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Forskningsöversikt (refereegranskat)abstract
- Zinc oxide (ZnO) is a thermally stable n-type semiconducting material. ZnO 2D nanosheets have mainly gained substantial attention due to their unique properties, such as direct bandgap and strong excitonic binding energy at room temperature. These are widely utilized in piezotronics, energy storage, photodetectors, light-emitting diodes, solar cells, gas sensors, and photocatalysis. Notably, the chemical properties and performances of ZnO nanosheets largely depend on the nano-structuring that can be regulated and controlled through modulating synthetic strategies. Two synthetic approaches, top-down and bottom-up, are mainly employed for preparing ZnO 2D nanomaterials. However, owing to better results in producing defect-free nanostructures, homogenous chemical composition, etc., the bottom-up approach is extensively used compared to the top-down method for preparing ZnO 2D nanosheets. This review presents a comprehensive study on designing and developing 2D ZnO nanomaterials, followed by accenting its potential applications. To begin with, various synthetic strategies and attributes of ZnO 2D nanosheets are discussed, followed by focusing on methodologies and reaction mechanisms. Then, their deliberation toward batteries, supercapacitors, electronics/optoelectronics, photocatalysis, sensing, and piezoelectronic platforms are further discussed. Finally, the challenges and future opportunities are featured based on its current development.
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4. |
- Sartelli, Massimo, et al.
(författare)
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Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action
- 2023
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Ingår i: WORLD JOURNAL OF EMERGENCY SURGERY. - 1749-7922. ; 18:1
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Forskningsöversikt (refereegranskat)abstract
- Antibiotics are recognized widely for their benefits when used appropriately. However, they are often used inappropriately despite the importance of responsible use within good clinical practice. Effective antibiotic treatment is an essential component of universal healthcare, and it is a global responsibility to ensure appropriate use. Currently, pharmaceutical companies have little incentive to develop new antibiotics due to scientific, regulatory, and financial barriers, further emphasizing the importance of appropriate antibiotic use. To address this issue, the Global Alliance for Infections in Surgery established an international multidisciplinary task force of 295 experts from 115 countries with different backgrounds. The task force developed a position statement called WARNING (Worldwide Antimicrobial Resistance National/International Network Group) aimed at raising awareness of antimicrobial resistance and improving antibiotic prescribing practices worldwide. The statement outlined is 10 axioms, or "golden rules," for the appropriate use of antibiotics that all healthcare workers should consistently adhere in clinical practice.
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