| 1. |
- Davies, G., et al.
(författare)
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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
- 2018
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Ingår i: Nature Communications. - : Nature Publishing Group. - 2041-1723. ; 9:1
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Tidskriftsartikel (refereegranskat)abstract
- General cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank (total N = 300,486; age 16-102) and find 148 genome-wide significant independent loci (P < 5 × 10-8) associated with general cognitive function. Within the novel genetic loci are variants associated with neurodegenerative and neurodevelopmental disorders, physical and psychiatric illnesses, and brain structure. Gene-based analyses find 709 genes associated with general cognitive function. Expression levels across the cortex are associated with general cognitive function. Using polygenic scores, up to 4.3% of variance in general cognitive function is predicted in independent samples. We detect significant genetic overlap between general cognitive function, reaction time, and many health variables including eyesight, hypertension, and longevity. In conclusion we identify novel genetic loci and pathways contributing to the heritability of general cognitive function.
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| 2. |
- Bosson, J. K., et al.
(författare)
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Psychometric Properties and Correlates of Precarious Manhood Beliefs in 62 Nations
- 2021
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Ingår i: Journal of Cross-Cultural Psychology. - : SAGE Publications. - 0022-0221 .- 1552-5422. ; 52:3
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Tidskriftsartikel (refereegranskat)abstract
- Precarious manhood beliefs portray manhood, relative to womanhood, as a social status that is hard to earn, easy to lose, and proven via public action. Here, we present cross-cultural data on a brief measure of precarious manhood beliefs (the Precarious Manhood Beliefs scale [PMB]) that covaries meaningfully with other cross-culturally validated gender ideologies and with country-level indices of gender equality and human development. Using data from university samples in 62 countries across 13 world regions (N = 33,417), we demonstrate: (1) the psychometric isomorphism of the PMB (i.e., its comparability in meaning and statistical properties across the individual and country levels); (2) the PMB's distinctness from, and associations with, ambivalent sexism and ambivalence toward men; and (3) associations of the PMB with nation-level gender equality and human development. Findings are discussed in terms of their statistical and theoretical implications for understanding widely-held beliefs about the precariousness of the male gender role.
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| 3. |
- Lahti, M., et al.
(författare)
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The required knowledge for lifespan mental health promotion and prevention for Master’s level mental health nurse education – the eMenthe project
- 2018
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Ingår i: International Journal of Health Promotion and Education. - Abingdon : Routledge. - 1463-5240 .- 2164-9545. ; 56:3, s. 143-154
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Tidskriftsartikel (refereegranskat)abstract
- In this study, we address the kind of knowledge that is required for Master’s level nurse education for lifespan mental health promotion and prevention. Data were collected through structured interviews (N = 109). The interviews were conducted across five European countries. The data were analysed using a thematic content analysis approach. The findings show that Master’s level nurse education needs knowledge related to lifespan issues. Needs were raised in several issues like importance of increasing skills and knowledge of mental health workers. We conclude that there is a need to emphasise the knowledge required for mental health promotion and prevention for Master’s level nursing education across Europe. © 2018 Institute of Health Promotion and Education.
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| 4. |
- Jaunsen, Andreas O., et al.
(författare)
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Nordic FAIR Data Collaboration Opportunities
- 2021
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Rapport (refereegranskat)abstract
- Executive summaryIn September 2020 the NeIC Director and board initiated a working group on FAIR collaborationopportunities in the Nordics. This came in the wake of the data tsunami era and the realisationthat machine learning and connected data will become of crucial importance to society andscience. Furthermore, the findings of the EOSC-Nordic project show that the FAIR uptake in theregion is slow and a majority of data repositories are not FAIR, while only a small fractionmeasures up to the available FAIR metrics. Sharing publicly-funded data in a meaningful,reusable way must become part of the normative behaviour in order to nurture data-drivensciences. By enabling data capabilities we are facilitating interdisciplinary data reuse, along withinformation and knowledge exchange. A key objective is data integration, where concepts andproperties, and the relationships between them are linked, forming knowledge graphs andproviding an opportunity to provide insight (new knowledge) from the multitude of relations andpatterns.Although FAIR awareness is growing and there is an appreciation of the Open Science visionamong researchers and support staff, a small survey conducted by the working group confirmssome challenges that are contradictory to the Open Science (OS) movement and contribute toconfusion and status quo when it comes to implementing FAIR. If we are serious aboutembracing OS and the implementation of the FAIR principles it is necessary to ensure that allelements pull in the same direction (this includes infrastructure, skills and services to policiesand incentives). Data stewardship is gradually becoming part of the researcher workflow insome organisations, institutions and departments. Professionalising this crucial support is key tosucceeding in a swift and effective transition to sharing discoverable, accessible and reusabledata. The working group finds that coordinating tasks such as raising awareness, training andskills development and developing common tools and services for research data management(RDM) can contribute to strengthen the momentum of FAIR uptake and better utilise resources,skills and tools across the Nordics. A Nordic coordination office may be one way to orchestratea common strategy on working towards the realisation of the Open Science vision.
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