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Sökning: WFRF:(Lindström Magnus)

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1.
  • Ahlford, Marianne, et al. (författare)
  • Uppsala Underdogs - A Robot Soccer Project
  • 2006
  • Rapport (populärvet., debatt m.m.)abstract
    • In this paper, we describe the four-legged soccer team Uppsala Underdogs developed by a group of 4th year computer science students at Uppsala University during the fall of 2004. The project is based on the experience from two similar previous projects. This year the emphasis of the project has been on distribution of data and on support for evaluation and reconfiguration of strategies. To support data distribution, a middleware has been developed, which implements a replication algorithm and provides a clean interface for the other software modules (or behaviors). To enable easy reconfiguration of strategies, an automata-based graphical description language has been developed, which can be compiled into code that uses the database and the lower level modules, such as tactics and positioning, to make decisions and control the robot. In addition, a graphical simulator has been developed in which the strategies can be evaluated.
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2.
  • Anderson, Helén, et al. (författare)
  • Skapa kundnärvaro i innovationsprocessen
  • 2008
  • Ingår i: Innovationsförmåga. - Malmö : Holmbergs i Malmö AB. - 9789197785204 ; , s. 40-59
  • Bokkapitel (populärvet., debatt m.m.)
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3.
  • Jiao, Fei, et al. (författare)
  • Nanofibrillated Cellulose-Based Electrolyte and Electrode for Paper-Based Supercapacitors
  • 2018
  • Ingår i: ADVANCED SUSTAINABLE SYSTEMS. - : Wiley. - 2366-7486. ; 2:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Solar photovoltaic technologies could fully deploy and impact the energy conversion systems in our society if mass-produced energy-storage solutions exist. A supercapacitor can regulate the fluctuations on the electrical grid on short time scales. Their mass-implementation requires the use of abundant materials, biological and organic synthetic materials are attractive because of atomic element abundancy and low-temperature synthetic processes. Nanofibrillated cellulose (NFC) coming from the forest industry is exploited as a three-dimensional template to control the transport of ions in an electrolyte-separator, with nanochannels filled of aqueous electrolyte. The nanochannels are defined by voids in the nanocomposite made of NFC and the proton transporting polymer polystyrene sulfonic acid PSSH. The ionic conductivity of NFC-PSSH composites (0.2 S cm(-1) at 100% relative humidity) exceeds sea water in a material that is solid, feel dry to the finger, but filled of nanodomains of water. A paper-based supercapacitor made of NFC-PSSH electrolyte-separator sandwiched between two paper-based electrodes is demonstrated. Although modest specific capacitance (81.3 F g(-1)), power density (2040 W kg(-1)) and energy density (1016 Wh kg(-1)), this is the first conceptual demonstration of a supercapacitor based on cellulose in each part of the device; which motivates the search for using paper manufacturing as mass-production of energy-storage devices.
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4.
  • Leion, Felicia, et al. (författare)
  • Estimating glomerular filtration rate (GFR) in children. The average between a cystatin C- and a creatinine-based equation improves estimation of GFR in both children and adults and enables diagnosing Shrunken Pore Syndrome.
  • 2017
  • Ingår i: Scandinavian Journal of Clinical and Laboratory Investigation. - : Informa UK Limited. - 0036-5513 .- 1502-7686. ; 77:5, s. 338-344
  • Tidskriftsartikel (refereegranskat)abstract
    • Estimating glomerular filtration rate (GFR) in adults by using the average of values obtained by a cystatin C- (eGFRcystatin C) and a creatinine-based (eGFRcreatinine) equation shows at least the same diagnostic performance as GFR estimates obtained by equations using only one of these analytes or by complex equations using both analytes. Comparison of eGFRcystatin C and eGFRcreatinine plays a pivotal role in the diagnosis of Shrunken Pore Syndrome, where low eGFRcystatin C compared to eGFRcreatinine has been associated with higher mortality in adults. The present study was undertaken to elucidate if this concept can also be applied in children. Using iohexol and inulin clearance as gold standard in 702 children, we studied the diagnostic performance of 10 creatinine-based, 5 cystatin C-based and 3 combined cystatin C-creatinine eGFR equations and compared them to the result of the average of 9 pairs of a eGFRcystatin C and a eGFRcreatinine estimate. While creatinine-based GFR estimations are unsuitable in children unless calibrated in a pediatric or mixed pediatric-adult population, cystatin C-based estimations in general performed well in children. The average of a suitable creatinine-based and a cystatin C-based equation generally displayed a better diagnostic performance than estimates obtained by equations using only one of these analytes or by complex equations using both analytes. Comparing eGFRcystatin and eGFRcreatinine may help identify pediatric patients with Shrunken Pore Syndrome.
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5.
  • Lindström, John, et al. (författare)
  • A development process for Functional Products : hardware, software, service support system and management of operation
  • 2012
  • Ingår i: International Journal of Product Development. - : InderScience Publishers. - 1477-9056 .- 1741-8178. ; 16:3/4, s. 284-303
  • Tidskriftsartikel (refereegranskat)abstract
    • The development process for a Functional Product (FP) is complex and there is a need to coordinate, monitor, control and share information as well as to communicate properly among the parties involved in the process. This paper proposes a conceptual development process to manage the FP development, including development of hardware, software, service support system, and how to manage the operation of an FP. Further, challenges related to the integrated development of FPs are also discussed.
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6.
  • Lindström, John, et al. (författare)
  • Functional product development : what information should be shared during the development process?
  • 2012
  • Ingår i: International Journal of Product Development. - : InderScience Publishers. - 1477-9056 .- 1741-8178. ; 16:2, s. 95-111
  • Tidskriftsartikel (refereegranskat)abstract
    • The development process for a Functional Product (FP) is complex and there is a need to share information as well as to communicate it among the parties involved in the process. The paper concerns shared information that is of specific interest when developing FPs, in contrast to information that must be shared during a general product or service development process. The findings are compiled in a conceptual table comprising such specific information items pertaining to both the initial development as well as post development parts of an FPs lifecycle. This table can be used as an aid to any development process or method, as it points out information items that must necessarily be shared, but not how they to be shared.
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7.
  • Lindström, John, et al. (författare)
  • Functional product development : what information should be shared during the development process?
  • 2012
  • Ingår i: International Journal of Product Development. - : InderScience Publishers. - 1477-9056 .- 1741-8178. ; 16:2, s. 95-111
  • Tidskriftsartikel (refereegranskat)abstract
    • The development process for a Functional Product (FP) is complex and there is a need to share information as well as to communicate it among the parties involved in the process. The paper concerns shared information that is of specific interest when developing FPs, in contrast to information that must be shared during a general product or service development process. The findings are compiled in a conceptual table comprising such specific information items pertaining to both the initial development as well as post development parts of an FPs lifecycle. This table can be used as an aid to any development process or method, as it points out information items that must necessarily be shared, but not how they to be shared.
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8.
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9.
  • Malmgren, Linnea, et al. (författare)
  • The complexity of kidney disease and diagnosing it - Cystatin C, selective glomerular hypofiltration syndromes and proteome regulation.
  • 2023
  • Ingår i: Journal of Internal Medicine. - : John Wiley & Sons. - 0954-6820 .- 1365-2796. ; 293:3, s. 293-308
  • Tidskriftsartikel (refereegranskat)abstract
    • Estimation of kidney function is often part of daily clinical practice, mostly done by using the endogenous GFR-markers creatinine or cystatin C. A recommendation to use both markers in parallel in 2010 has resulted in new knowledge concerning the pathophysiology of kidney disorders by identification of a new set of kidney disorders, selective glomerular hypofiltration syndromes. These syndromes, connected to strong increases in mortality and morbidity, are characterised by a selective reduction in the glomerular filtration of 5-30 kDa molecules, such as cystatin C, compared to the filtration of small molecules < 1kDa dominating the glomerular filtrate e.g., water, urea, creatinine. At least two types of such disorders, shrunken or elongated pore syndrome, are possible according to the pore model for glomerular filtration. Selective glomerular hypofiltration syndromes are prevalent in investigated populations, and patients with these syndromes often display normal measured GFR or creatinine-based GFR-estimates. The syndromes are characterised by proteomic changes promoting the development of atherosclerosis, indicating antibodies and specific receptor-blocking substances as possible new treatment modalities. Presently, the KDIGO guidelines for diagnosing kidney disorders do not recommend cystatin C as a general marker of kidney function and will therefore not allow the identification of a considerable number of patients with selective glomerular hypofiltration syndromes. Furthermore, as cystatin C is uninfluenced by muscle mass, diet or variations in tubular secretion and cystatin C-based GFR-estimation equations do not require controversial race or sex terms, it is obvious that cystatin C should be a part of future KDIGO guidelines.
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10.
  • Sällman Almén, Markus, et al. (författare)
  • Shrunken Pore Syndrome Is Associated With Increased Levels of Atherosclerosis-Promoting Proteins
  • 2019
  • Ingår i: Kidney International Reports. - : Elsevier BV. - 2468-0249. ; 4:1, s. 67-79
  • Tidskriftsartikel (refereegranskat)abstract
    • Introduction: Shrunken pore syndrome (SPS), originally defined by cystatin C-based estimated glomerular filtration rate (eGFRcystatin C) being less than 60% of creatinine-based estimated glomerular filtration rate (eGFRcreatinine) in the absence of extrarenal influences on the plasma levels of cystatin C or creatinine, is associated with a high increase in mortality, even in the absence of reduced glomerular filtration rate (GFR). The objective of the present study was to determine whether the proteome of patients with SPS shows differences from that of patients with normal or reduced measured GFR (mGFR) without SPS.Methods: Four patient cohorts were included: 1 cohort with normal mGFR without SPS, 1 with normal mGFR with SPS, 1 with reduced mGFR without SPS, and 1 with reduced mGFR with SPS. The plasma levels of 177 selected proteins were analyzed.Results: Differences in the levels of 30 proteins were specific for SPS; 31 differences were specific for patients with both SPS and reduced mGFR; and 27 were specific for reduced mGFR. Eighteen of the differences specific for SPS concerned proteins described as promoting, or being associated with, atherosclerosis. Twelve of the differences specific for patients with both SPS and reduced mGFR and 10 of the differences specific for reduced mGFR also concerned proteins described as promoting, or being associated with, atherosclerosis. Almost all (82 of 88) of the concentration differences represented increased levels. For SPS, but not for reduced mGFR, a correlation between protein size and increase in level was observed, with smaller proteins being associated with higher levels.Conclusion: The high mortality in shrunken pore syndrome might be caused by the accumulation of atherosclerosis-promoting proteins in this condition.
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