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- Barany, E, et al.
(author)
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Mercury and selenium in whole blood and serum in relation to fish consumption and amalgam fillings in adolescents
- 2003
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In: Journal of Trace Elements in Medicine and Biology. - 1878-3252 .- 0946-672X. ; 17:3, s. 165-170
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Journal article (peer-reviewed)abstract
- Mercury and selenium in whole blood and serum of 245 17-year old Swedish adolescents were analysed. The relationships between these elements' concentrations and the consumption of fish as well as the number of dental amalgam fillings were studied. The geometric means (GM) of the mercury concentrations were 1.1 mug/L in blood and 0.43 mug/L in serum. The mean selenium concentration in blood was 110 mug/L and the GM of the serum selenium concentration 110 mug/L. Fish species with dietary restrictions due to elevated mercury Levels (i.e. pike, perch, pikeperch, burbot, eel and halibut) were consumed on average 0.7 times/month and fish species without such restrictions 4.1 times/month. Despite this comparatively Low fish consumption, the adolescents' blood mercury concentrations were positively correlated with fish consumption. Of the adolescents, 39% had amalgam fillings (mean 2 +/- 1.5). Serum mercury was influenced by the number of amalgam fittings, by fish consumption, blood and serum levels of selenium and the residential area. Blood and serum selenium concentrations were not influenced by fish consumption, but were positively associated with the serum mercury concentration.
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| 3. |
- Barany, E, et al.
(author)
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Relationships between trace element concentrations in human blood and serum
- 2002
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In: Toxicology Letters. - 1879-3169 .- 0378-4274. ; 134:1-3, s. 177-184
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Journal article (peer-reviewed)abstract
- Trace element interactions can affect the absorption, metabolism, or effects of elements. Also, different elements may derive from the same source. Associations in biological media between element concentrations may indicate such phenomena. A large number of correlations were found between 13 trace elements (Co, Cu, Zn, Se, Rb, Rh, Pd, Cd, W, Pt, Hg, Tl, and Pb) in human blood and/or serum, as investigated in 372 Swedish adolescents. Notably, serum Se correlated with blood Ph and blood Hg and Cu and Zn were correlated to each other in both blood and serum. The elements Pt, Pd and Rh, spread in the environment through use of catalytic converters in cars, were closely correlated in both blood and serum. Apart from the correlations with a probable biological or exposure-related explanation, several other correlations, of yet unknown importance and origin, were found.
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| 4. |
- Barany, E, et al.
(author)
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Trace element levels in whole blood and serum from Swedish adolescents
- 2002
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In: Science of the Total Environment. - 1879-1026 .- 0048-9697. ; 286:1-3, s. 129-141
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Journal article (peer-reviewed)abstract
- Blood and serum samples from 372 15-year-old adolescents were collected in two cities in Sweden and analyzed by inductively coupled plasma mass spectrometry (ICP-MS). The objective was to (1) determine the levels of 13 elements in blood and serum from the teenagers; and (2) for each element, investigate the correlation between the concentrations in blood and serum. The concentrations in blood and serum were generally in line with that usually reported for the essential elements Co, Cu, Zn and Se, and generally low for the 'non-essential' elements Cd, Hg, Pb. The median concentrations were in blood and serum, respectively: of Co 031 and 0.48 mug/l, Cu 0.92 and 1.0 mg/l, Zn 6.1 and 0.99 mg/l, Se 110 and 100 mug/l, Rb 2.8 and 0.24 mg/l, Hg 1.1 and 0.44 mug/l, Pb 16 and 0.33 mug/l. The median concentration of W in blood was < 0.2 mug/l (below the detection limit) and in serum 0.087 mug/l. The median concentrations of Cd, Rh, Pd, Pt and TI were below the detection limits. Statistically significant correlations were found between the concentrations in blood and serum for Co, Cu, Zn, Se, Rb, W, Hg and Pb. The levels presented in this study constitute baseline levels or levels generally not exceeded in adolescents for 13 elements, including essential, ubiquitous toxic, and rare elements.
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| 5. |
- Barany, E, et al.
(author)
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Trace elements in blood and serum of Swedish adolescents: Relation to gender, age, residential area, and socioeconomic status
- 2002
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In: Environmental Research. - : Elsevier BV. - 1096-0953 .- 0013-9351. ; 89:1, s. 72-84
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Journal article (peer-reviewed)abstract
- The influence of gender, age, residential area, and socioeconomic status on the blood and serum levels of 13 trace elements was studied in boys and girls living in two Swedish cities with different socioeconomic and environmental characters. The same groups of adolescents were sampled twice, at ages 15 (n = 372) and 17 (n = 294) years. All the investigated factors were shown to be of importance. Age was important for most elements; e.g., copper levels in both blood and serum increased in girls, and selenium increased in serum from both genders. Lead decreased approximately 10%, in blood from the first to the second sampling, and cadmium increased in blood, however not in nonsmokers. The age factor may also reflect temporal changes in environmental exposure, especially for nonessential elements. Girls had higher levels of cobalt and copper, while lead in blood was higher in boys. Smoking girls had higher copper levels than nonsmoking girls. Residential area influenced all elements. The teenagers with university-educated mothers had higher levels of cadmium in blood than those with only primary school-educated mothers.
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| 6. |
- Linden, A, et al.
(author)
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Monitoring of cadmium in the chain from soil via crops and feed to pig blood and kidney
- 2003
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In: Ecotoxicology and Environmental Safety. - 0147-6513. ; 55:2, s. 213-222
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Journal article (peer-reviewed)abstract
- The relationships between cadmium (Cd) levels in soil, feed crops, feed concentrate, pig feed mixture, water, pig blood, and kidney from 49 farms were investigated and the possibility to use pig kidney as a bioindicator of available Cd in the agricultural environment was evaluated. There were correlations between Cd levels in soil and wheat, between wheat and barley, and between feed and kidney. The accumulation ratio between Cd levels in feed and kidney was on average 3. Animals from the same farm, raised in the same environment, given the same feed, and slaughtered at the same age had Cd levels in kidney and blood that could differ several times. This great variation, together with a considerable Cd contribution from nonlocally produced feed ingredients (concentrates). limits the possibilities to use Cd in pig kidney as an indicator of the available Cd in the local environment. (C) 2003 Elsevier Science (USA). All rights reserved.
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| 7. |
- Olsson, Ing-Marie, et al.
(author)
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Cadmium in blood and urine - Impact of sex, age, dietary intake, iron status, and former smoking - Association of renal effects
- 2002
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In: Environmental Health Perspectives. - 1552-9924. ; 110:12, s. 1185-1190
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Journal article (peer-reviewed)abstract
- We studied determinants of cadmium status and kidney function in nonsmoking men and women living on farms in southern Sweden. Median blood Cd (BCd) was 1.8 nmol/L (range, 0.38-18) and median urinary Cd (UCd) was 0.23 nmol/mmol creatinine (range, 0.065-0.99). The intake of Cd per kilogram body weight did not significantly differ between sexes and did not correlate with BCd or UCd, which may be explained by a low and varying bioavailibility of Cd from food items. However, when a subgroup of the study population, couples of never-smoking men and women, were compared, a lower intake per kilogram body weight was found in the women, but the women had a 1.8 times higher BCd and a 1.4 times higher UCd. The higher female BCd and UCd may be explained by higher absorption due to low iron status. BCd and UCd both increased with age and were higher in the ex-smokers, who had stopped smoking more than 5 years before the study, compared to never-smokers. The contribution of locally produced food to the total Cd intake was relatively low and varied. Males living in areas with low soil Cd had lower UCd than the others. However, Cd levels in kidneys from pigs, fed locally produced cereals, did not predict BCd or UCd in humans at the same farms. The kidney function parameter beta(2)-microglobulin-creatinine clearance was related to UCd, whereas urinary protein-HC, N-acetyl-beta-glucoseaminidase or albumin-creatinine clearance was not when age was accounted for. Hence, even. at the, low exposure levels in this study population, there was an indication of effect on biochemical markers of renal function.
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