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Toward Male Individ...
Toward Male Individualization with Rapidly Mutating Y-Chromosomal Short Tandem Repeats
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- Ballantyne, Kaye N. (author)
- Erasmus MC University, Netherlands Victoria Police Forens Serv Department, Australia
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- Ralf, Arwin (author)
- Erasmus MC University, Netherlands
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- Aboukhalid, Rachid (author)
- Mohammed V Agdal University, Morocco
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show more...
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- Achakzai, Niaz M. (author)
- University of Punjab, Pakistan
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- Anjos, Maria J. (author)
- National Institute Legal Medical and Forens Science IP, Portugal
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- Ayub, Qasim (author)
- Wellcome Trust Sanger Institute, England
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- Balazic, Joze (author)
- University of Ljubljana, Slovenia
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- Ballantyne, Jack (author)
- University of Central Florida, FL 32816 USA University of Central Florida, FL 32816 USA
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- J. Ballard, David (author)
- Kings Coll London, England
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- Berger, Burkhard (author)
- Medical University of Innsbruck, Austria
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- Bobillo, Cecilia (author)
- University of Buenos Aires, Argentina Consejo Nacl Invest Cient and Tecn, Argentina
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- Bouabdellah, Mehdi (author)
- Mohammed V Agdal University, Morocco
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- Burri, Helen (author)
- University of Zurich, Switzerland
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- Capal, Tomas (author)
- Institute Criminalist Prague, Czech Republic
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- Caratti, Stefano (author)
- University of Turin, Italy
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- Cardenas, Jorge (author)
- University of Santiago de Compostela, Spain
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- Cartault, Francois (author)
- Site Centre Hospital Felix Guyon, Reunion
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- F. Carvalho, Elizeu (author)
- University of Estado Rio De Janeiro, Brazil
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- Carvalho, Monica (author)
- National Institute Legal Medical and Forens Science IP, Portugal
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- Cheng, Baowen (author)
- Yunnan Prov Department Public Secur, Peoples R China
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- D. Coble, Michael (author)
- NIST, MD 20899 USA
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- Comas, David (author)
- University of Pompeu Fabra, Spain
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- Corach, Daniel (author)
- University of Buenos Aires, Argentina Consejo Nacl Invest Cient and Tecn, Argentina
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- E. DAmato, Maria (author)
- University of Western Cape, South Africa
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- Davison, Sean (author)
- University of Western Cape, South Africa
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- de Knijff, Peter (author)
- Leiden University, Netherlands
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- Corazon A. De Ungria, Maria (author)
- University of Philippines, Philippines
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- Decorte, Ronny (author)
- Katholieke University of Leuven, Belgium
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- Dobosz, Tadeusz (author)
- Wroclaw Medical University, Poland
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- M. Dupuy, Berit (author)
- Norwegian Institute Public Heatlh, Norway
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- Elmrghni, Samir (author)
- University of Benghazi, Libya
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- Gliwinski, Mateusz (author)
- Medical University of Gdansk, Poland
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- C. Gomes, Sara (author)
- University of Madeira, Portugal
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- Grol, Laurens (author)
- Netherlands Forens Institute, Netherlands
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- Haas, Cordula (author)
- University of Zurich, Switzerland
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- Hanson, Erin (author)
- University of Central Florida, FL 32816 USA
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- Henke, Juergen (author)
- Institute Blutgruppenforsch LGC GmbH, Germany
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- Henke, Lotte (author)
- Institute Blutgruppenforsch LGC GmbH, Germany
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- Herrera-Rodriguez, Fabiola (author)
- Poder Judicial, Costa Rica
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- R. Hill, Carolyn (author)
- NIST, MD 20899 USA
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- Holmlund, Gunilla (author)
- Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Hälsouniversitetet
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- Honda, Katsuya (author)
- University of Tsukuba, Japan
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- Immel, Uta-Dorothee (author)
- University of Halle Wittenberg, Germany
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- Inokuchi, Shota (author)
- National Research Institute Police Science, Japan
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- A. Jobling, Mark (author)
- University of Leicester, England
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- Kaddura, Mahmoud (author)
- University of Benghazi, Libya
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- S. Kim, Jong (author)
- Supreme Prosecutors Off, South Korea
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- H. Kim, Soon (author)
- National Forens Serv, South Korea
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- Kim, Wook (author)
- Dankook University, South Korea
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- E. King, Turi (author)
- University of Leicester, England
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- Klausriegler, Eva (author)
- Salzburg University, Austria
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- Kling, Daniel (author)
- Norwegian Institute Public Heatlh, Norway
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- Kovacevic, Lejla (author)
- Institute Genet Engn and Biotechnol, Bosnia and Herceg
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- Kovatsi, Leda (author)
- Aristotle University of Thessaloniki, Greece
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- Krajewski, Pawel (author)
- Medical University of Warsaw, Poland
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- Kravchenko, Sergey (author)
- NASU, Ukraine
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- H. D. Larmuseau, Maarten (author)
- Katholieke University of Leuven, Belgium
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- Young Lee, Eun (author)
- Yonsei University, South Korea
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- Lessig, Ruediger (author)
- University of Halle Wittenberg, Germany
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- A. Livshits, Ludmila (author)
- NASU, Ukraine
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- Marjanovic, Damir (author)
- Institute Genet Engn and Biotechnol, Bosnia and Herceg
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- Minarik, Marek (author)
- Genomac Forens Institute, Czech Republic
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- Mizuno, Natsuko (author)
- National Research Institute Police Science, Japan
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- Moreira, Helena (author)
- University of Aveiro, Portugal
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- Morling, Niels (author)
- University of Copenhagen, Denmark
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- Mukherjee, Meeta (author)
- Govt India, India
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- Munier, Patrick (author)
- Site Centre Hospital Felix Guyon, Reunion
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- Nagaraju, Javaregowda (author)
- Centre DNA Fingerprinting and Diagnost, India
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- Neuhuber, Franz (author)
- Salzburg University, Austria
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- Nie, Shengjie (author)
- Kunming Medical University, Peoples R China
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- Nilasitsataporn, Premlaphat (author)
- Royal Thai Police, Thailand
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- Nishi, Takeki (author)
- University of Tsukuba, Japan
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- H. Oh, Hye (author)
- Supreme Prosecutors Off, South Korea
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- Olofsson, Jill (author)
- University of Copenhagen, Denmark
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- Onofri, Valerio (author)
- University of Politecn Marche, Italy
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- U. Palo, Jukka (author)
- University of Helsinki, Finland
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- Pamjav, Horolma (author)
- Minist Public Adm and Justice, Hungary
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- Parson, Walther (author)
- Medical University of Innsbruck, Austria Penn State University, PA 16802 USA
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- Petlach, Michal (author)
- Genomac Forens Institute, Czech Republic
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- Phillips, Christopher (author)
- University of Santiago de Compostela, Spain
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- Ploski, Rafal (author)
- Medical University of Warsaw, Poland
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- P. R. Prasad, Samayamantri (author)
- Centre DNA Fingerprinting and Diagnost, India
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- Primorac, Dragan (author)
- Penn State University, PA 16802 USA University of New Haven, CT USA University of Split, Croatia University of Osijek, Croatia
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- A. Purnomo, Gludhug (author)
- Eijkman Institute Molecular Biol, Indonesia
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- Purps, Josephine (author)
- Charite, Germany
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- Rangel-Villalobos, Hector (author)
- University of Guadalajara CUCienega UdeG, Mexico
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- Rebala, Krzysztof (author)
- Medical University of Gdansk, Poland
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- Rerkamnuaychoke, Budsaba (author)
- Mahidol University, Thailand
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- Rey Gonzalez, Danel (author)
- University of Santiago de Compostela, Spain
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- Robino, Carlo (author)
- University of Turin, Italy
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- Roewer, Lutz (author)
- Charite, Germany
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- Rosa, Alexandra (author)
- University of Madeira, Portugal University of Madeira, Portugal
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- Sajantila, Antti (author)
- University of Helsinki, Finland University of N Texas, TX USA
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- Sala, Andrea (author)
- University of Buenos Aires, Argentina Consejo Nacl Invest Cient and Tecn, Argentina
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- M. Salvador, Jazelyn (author)
- University of Philippines, Philippines
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- Sanz, Paula (author)
- University of Pompeu Fabra, Spain
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- Schmitt, Cornelia (author)
- University of Cologne, Germany
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- K. Sharma, Anil (author)
- Govt India, India
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- A. Silva, Dayse (author)
- University of Estado Rio De Janeiro, Brazil
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- Shin, Kyoung-Jin (author)
- Yonsei University, South Korea
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- Sijen, Titia (author)
- Netherlands Forens Institute, Netherlands
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- Sirker, Miriam (author)
- University of Cologne, Germany
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- Sivakova, Daniela (author)
- Comenius University, Slovakia
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- Skaro, Vedrana (author)
- Genos Ltd, Croatia
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- Solano-Matamoros, Carlos (author)
- University of Costa Rica, Costa Rica
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- Souto, Luis (author)
- University of Aveiro, Portugal
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- Stenzl, Vlastimil (author)
- Institute Criminalist Prague, Czech Republic
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- Sudoyo, Herawati (author)
- Eijkman Institute Molecular Biol, Indonesia
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- Syndercombe-Court, Denise (author)
- Kings Coll London, England
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- Tagliabracci, Adriano (author)
- University of Politecn Marche, Italy
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- Taylor, Duncan (author)
- Forens Science South Australia, Australia Flinders University of S Australia, Australia
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- Tillmar, Andreas (author)
- Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Hälsouniversitetet,Natl Board Forens Med, Dept Forens Genet and Forens Toxicol, Linkoping, Sweden
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- S. Tsybovsky, Iosif (author)
- State Comm Forens Expertises, Byelarus
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- Tyler-Smith, Chris (author)
- Wellcome Trust Sanger Institute, England
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- J. van der Gaag, Kristiaan (author)
- Leiden University, Netherlands
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- Vanek, Daniel (author)
- Forens DNA Serv, Czech Republic Charles University of Prague, Czech Republic
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- Volgyi, Antonia (author)
- Minist Public Adm and Justice, Hungary
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- Ward, Denise (author)
- Forens Science South Australia, Australia
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- Willemse, Patricia (author)
- Leiden University, Netherlands
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- P. H. Yap, Eric (author)
- DSO National Labs, Singapore
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- Y. Y. Yong, Rita (author)
- DSO National Labs, Singapore
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- Zupanic Pajnic, Irena (author)
- University of Ljubljana, Slovenia
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- Kayser, Manfred (author)
- Erasmus MC University, Netherlands
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(creator_code:org_t)
- 2014-07-14
- 2014
- English.
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In: Human Mutation. - : John Wiley & Sons. - 1059-7794 .- 1098-1004. ; 35:8, s. 1021-1032
- Related links:
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https://liu.diva-por... (primary) (Raw object)
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https://onlinelibrar...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
Close
- Relevant for various areas of human genetics, Y-chromosomal short tandem repeats (Y-STRs) are commonly used for testing close paternal relationships among individuals and populations, and for male lineage identification. However, even the widely used 17-loci Yfiler set cannot resolve individuals and populations completely. Here, 52 centers generated quality-controlled data of 13 rapidly mutating (RM) Y-STRs in 14,644 related and unrelated males from 111 worldwide populations. Strikingly, greater than99% of the 12,272 unrelated males were completely individualized. Haplotype diversity was extremely high (global: 0.9999985, regional: 0.99836-0.9999988). Haplotype sharing between populations was almost absent except for six (0.05%) of the 12,156 haplotypes. Haplotype sharing within populations was generally rare (0.8% nonunique haplotypes), significantly lower in urban (0.9%) than rural (2.1%) and highest in endogamous groups (14.3%). Analysis of molecular variance revealed 99.98% of variation within populations, 0.018% among populations within groups, and 0.002% among groups. Of the 2,372 newly and 156 previously typed male relative pairs, 29% were differentiated including 27% of the 2,378 father-son pairs. Relative to Yfiler, haplotype diversity was increased in 86% of the populations tested and overall male relative differentiation was raised by 23.5%. Our study demonstrates the value of RMY-STRs in identifying and separating unrelated and related males and provides a reference database.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap -- Rättsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences -- Forensic Science (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Cell- och molekylärbiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Cell and Molecular Biology (hsv//eng)
Keyword
- Y-chromosome; Y-STRs; haplotypes; RM Y-STRs; paternal lineage; forensic
Publication and Content Type
- ref (subject category)
- art (subject category)
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Ballantyne, Kaye ...
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Ralf, Arwin
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Aboukhalid, Rach ...
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Achakzai, Niaz M ...
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Anjos, Maria J.
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Ayub, Qasim
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Balazic, Joze
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Ballantyne, Jack
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J. Ballard, Davi ...
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Berger, Burkhard
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Bobillo, Cecilia
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Bouabdellah, Meh ...
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Burri, Helen
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Capal, Tomas
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Caratti, Stefano
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Cardenas, Jorge
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Cartault, Franco ...
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F. Carvalho, Eli ...
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Carvalho, Monica
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Cheng, Baowen
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D. Coble, Michae ...
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Comas, David
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Corach, Daniel
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E. DAmato, Maria
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Davison, Sean
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de Knijff, Peter
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Corazon A. De Un ...
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Decorte, Ronny
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Dobosz, Tadeusz
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M. Dupuy, Berit
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Elmrghni, Samir
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Gliwinski, Mateu ...
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C. Gomes, Sara
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Grol, Laurens
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Haas, Cordula
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Hanson, Erin
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Henke, Juergen
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Henke, Lotte
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Herrera-Rodrigue ...
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R. Hill, Carolyn
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Holmlund, Gunill ...
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Honda, Katsuya
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Immel, Uta-Dorot ...
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Inokuchi, Shota
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A. Jobling, Mark
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Kaddura, Mahmoud
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S. Kim, Jong
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H. Kim, Soon
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Kim, Wook
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E. King, Turi
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Klausriegler, Ev ...
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Kling, Daniel
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Kovacevic, Lejla
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Kovatsi, Leda
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Krajewski, Pawel
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Kravchenko, Serg ...
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H. D. Larmuseau, ...
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Young Lee, Eun
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Lessig, Ruediger
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A. Livshits, Lud ...
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Marjanovic, Dami ...
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Minarik, Marek
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Mizuno, Natsuko
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Moreira, Helena
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Morling, Niels
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Mukherjee, Meeta
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Munier, Patrick
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Nagaraju, Javare ...
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Neuhuber, Franz
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Nie, Shengjie
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Nilasitsataporn, ...
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Nishi, Takeki
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H. Oh, Hye
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Olofsson, Jill
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Onofri, Valerio
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U. Palo, Jukka
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Pamjav, Horolma
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Parson, Walther
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Petlach, Michal
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Phillips, Christ ...
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Ploski, Rafal
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P. R. Prasad, Sa ...
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Primorac, Dragan
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A. Purnomo, Glud ...
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Purps, Josephine
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Rangel-Villalobo ...
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Rebala, Krzyszto ...
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Rerkamnuaychoke, ...
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Rey Gonzalez, Da ...
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Robino, Carlo
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Roewer, Lutz
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Rosa, Alexandra
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Sajantila, Antti
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Sala, Andrea
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M. Salvador, Jaz ...
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Sanz, Paula
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Schmitt, Corneli ...
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K. Sharma, Anil
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A. Silva, Dayse
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Shin, Kyoung-Jin
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Sijen, Titia
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Sirker, Miriam
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Sivakova, Daniel ...
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Skaro, Vedrana
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Solano-Matamoros ...
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Souto, Luis
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Stenzl, Vlastimi ...
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Sudoyo, Herawati
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Syndercombe-Cour ...
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Tagliabracci, Ad ...
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Taylor, Duncan
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Tillmar, Andreas
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S. Tsybovsky, Io ...
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Tyler-Smith, Chr ...
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J. van der Gaag, ...
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Vanek, Daniel
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Volgyi, Antonia
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Ward, Denise
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Willemse, Patric ...
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P. H. Yap, Eric
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Y. Y. Yong, Rita
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Zupanic Pajnic, ...
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Kayser, Manfred
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Other Medical an ...
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and Forensic Science
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Cell and Molecul ...
- Articles in the publication
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Human Mutation
- By the university
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Linköping University