| 1. |
- Gawel, Danuta, et al.
(författare)
-
Clinical translation of genomic medicine : Stor potential när genomikdata kan implementeras i klinisk rutin.
- 2021
-
Ingår i: Läkartidningen. - 1652-7518. ; 118
-
Tidskriftsartikel (refereegranskat)abstract
- Recent technical developments and early clinical examples support that precision medicine has potential to provide novel diagnostic and therapeutic solutions for patients with complex diseases, who are not responding to existing therapies. Those solutions will require integration of genomic data with routine clinical, imaging, sensor, biobank and registry data. Moreover, user-friendly tools for informed decision support for both patients and clinicians will be needed. While this will entail huge technical, ethical, societal and regulatory challenges, it may contribute to transforming and improving health care towards becoming predictive, preventive, personalised and participatory (4P-medicine).
|
|
| 2. |
- Gawel, Danuta, 1988-, et al.
(författare)
-
Stor potential när genomikdatakan implementeras i klinisk rutin : [Clinical translation of genomic medicine]
- 2021
-
Ingår i: Läkartidningen. - : Sveriges Läkarförbund. - 0023-7205 .- 1652-7518. ; 118
-
Forskningsöversikt (refereegranskat)abstract
- Recent technical developments and early clinical examples support that precision medicine has potential to provide novel diagnostic and therapeutic solutions for patients with complex diseases, who are not responding to existing therapies. Those solutions will require integration of genomic data with routine clinical, imaging, sensor, biobank and registry data. Moreover, user-friendly tools for informed decision support for both patients and clinicians will be needed. While this will entail huge technical, ethical, societal and regulatory challenges, it may contribute to transforming and improving health care towards becoming predictive, preventive, personalised and participatory (4P-medicine).
|
|
| 3. |
- Melén, Erik, et al.
(författare)
-
Precision medicine in complex diseases : Precisionsmedicin kan bli viktig även vid komplexa sjukdomar.
- 2021
-
Ingår i: Läkartidningen. - 1652-7518. ; 118
-
Tidskriftsartikel (refereegranskat)abstract
- Complex diseases represent a number of common disorders such as allergic conditions, cardiovascular, metabolic and chronic inflammatory diseases. These diseases are caused by a combination of genetic, environmental and lifestyle factors. This complex etiology creates challenges when it comes to diagnostics, follow-up programs and treatment. Although exact disease mechanisms are yet to be elucidated for most complex diseases, key genetic determinants have been mapped and omics profiling has unraveled involved pathways. Using this wealth of data, precision medicine applications have started to appear also for common, complex diseases. In this article, we review current precision medicine applications from a clinical point of view and outline briefly a roadmap ahead for further clinical implementation of precision medicine in complex diseases.
|
|
| 4. |
- Melén, Erik, et al.
(författare)
-
Precisionsmedicin kan bli viktig även vid komplexa sjukdomar
- 2021
-
Ingår i: Lakartidningen. - 0023-7205. ; 118
-
Tidskriftsartikel (refereegranskat)abstract
- Complex diseases represent a number of common disorders such as allergic conditions, cardiovascular, metabolic and chronic inflammatory diseases. These diseases are caused by a combination of genetic, environmental and lifestyle factors. This complex etiology creates challenges when it comes to diagnostics, follow-up programs and treatment. Although exact disease mechanisms are yet to be elucidated for most complex diseases, key genetic determinants have been mapped and omics profiling has unraveled involved pathways. Using this wealth of data, precision medicine applications have started to appear also for common, complex diseases. In this article, we review current precision medicine applications from a clinical point of view and outline briefly a roadmap ahead for further clinical implementation of precision medicine in complex diseases.
|
|
| 5. |
|
|
| 6. |
- Melén, Sara, et al.
(författare)
-
Globala affärer : tidlösa principer och strategiska ramverk
- 2020
-
Bok (övrigt vetenskapligt/konstnärligt)abstract
- Många viktiga internationaliseringsbeslut fattas ofta på basis av magkänsla eller personliga kontakter på specifika marknader. Boken är skriven av forskare inom strategi och innovation vid Handelshögskolan i Stockholm och syftar till att sammanfatta relevant forskning och nya insikter på ett så praktiskt och lättillgängligt sätt som möjligt.
|
|
| 7. |
|
|
