SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Neill James D.) ;lar1:(lu)"

Sökning: WFRF:(Neill James D.) > Lunds universitet

  • Resultat 1-5 av 5
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  •  
2.
  •  
3.
  • Ferrari, Raffaele, et al. (författare)
  • Frontotemporal dementia and its subtypes: a genome-wide association study.
  • 2014
  • Ingår i: Lancet Neurology. - 1474-4465. ; 13:7, s. 686-699
  • Tidskriftsartikel (refereegranskat)abstract
    • Frontotemporal dementia (FTD) is a complex disorder characterised by a broad range of clinical manifestations, differential pathological signatures, and genetic variability. Mutations in three genes-MAPT, GRN, and C9orf72-have been associated with FTD. We sought to identify novel genetic risk loci associated with the disorder.
  •  
4.
  • Anderson, Cynthia M., et al. (författare)
  • Permanent Genetic Resources added to Molecular Ecology Resources Database 1 December 2009-31 January 2010
  • 2010
  • Ingår i: Molecular Ecology Resources. - : Wiley. - 1755-098X .- 1755-0998. ; 10:3, s. 576-579
  • Tidskriftsartikel (refereegranskat)abstract
    • This article documents the addition of 220 microsatellite marker loci to the Molecular Ecology Resources Database. Loci were developed for the following species: Allanblackia floribunda, Amblyraja radiata, Bactrocera cucurbitae, Brachycaudus helichrysi, Calopogonium mucunoides, Dissodactylus primitivus, Elodea canadensis, Ephydatia fluviatilis, Galapaganus howdenae howdenae, Hoplostethus atlanticus, Ischnura elegans, Larimichthys polyactis, Opheodrys vernalis, Pelteobagrus fulvidraco, Phragmidium violaceum, Pistacia vera, and Thunnus thynnus. These loci were cross-tested on the following species: Allanblackia gabonensis, Allanblackia stanerana, Neoceratitis cyanescens, Dacus ciliatus, Dacus demmerezi, Bactrocera zonata, Ceratitis capitata, Ceratitis rosa, Ceratits catoirii, Dacus punctatifrons, Ephydatia mulleri, Spongilla lacustris, Geodia cydonium, Axinella sp., Ischnura graellsii, Ischnura ramburii, Ischnura pumilio, Pistacia integerrima and Pistacia terebinthus.
  •  
5.
  • Manzoni, Claudia, et al. (författare)
  • Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia
  • 2024
  • Ingår i: American Journal of Human Genetics. - 0002-9297. ; 111:7, s. 1316-1329
  • Tidskriftsartikel (refereegranskat)abstract
    • Frontotemporal dementia (FTD) is the second most common cause of early-onset dementia after Alzheimer disease (AD). Efforts in the field mainly focus on familial forms of disease (fFTDs), while studies of the genetic etiology of sporadic FTD (sFTD) have been less common. In the current work, we analyzed 4,685 sFTD cases and 15,308 controls looking for common genetic determinants for sFTD. We found a cluster of variants at the MAPT (rs199443; p = 2.5 × 10−12, OR = 1.27) and APOE (rs6857; p = 1.31 × 10−12, OR = 1.27) loci and a candidate locus on chromosome 3 (rs1009966; p = 2.41 × 10−8, OR = 1.16) in the intergenic region between RPSA and MOBP, contributing to increased risk for sFTD through effects on expression and/or splicing in brain cortex of functionally relevant in-cis genes at the MAPT and RPSA-MOBP loci. The association with the MAPT (H1c clade) and RPSA-MOBP loci may suggest common genetic pleiotropy across FTD and progressive supranuclear palsy (PSP) (MAPT and RPSA-MOBP loci) and across FTD, AD, Parkinson disease (PD), and cortico-basal degeneration (CBD) (MAPT locus). Our data also suggest population specificity of the risk signals, with MAPT and APOE loci associations mainly driven by Central/Nordic and Mediterranean Europeans, respectively. This study lays the foundations for future work aimed at further characterizing population-specific features of potential FTD-discriminant APOE haplotype(s) and the functional involvement and contribution of the MAPT H1c haplotype and RPSA-MOBP loci to pathogenesis of sporadic forms of FTD in brain cortex.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-5 av 5
Typ av publikation
tidskriftsartikel (5)
Typ av innehåll
refereegranskat (5)
Författare/redaktör
Padovani, Alessandro (2)
Boada, Mercè (2)
Pasquier, Florence (2)
Nilsson, Christer (2)
van der Zee, Julie (2)
Van Broeckhoven, Chr ... (2)
visa fler...
Rademakers, Rosa (2)
Giaccone, Giorgio (2)
Tagliavini, Fabrizio (2)
Lleó, Alberto (2)
Clarimon, Jordi (2)
Cruchaga, Carlos (2)
Hardy, John (2)
Graff, Caroline (2)
Jakobsson, J. (2)
Borroni, Barbara (2)
Singleton, Andrew B. (2)
Bozhkov, Peter (2)
Rogaeva, Ekaterina (2)
Seeley, William W. (2)
Galimberti, Daniela (2)
Pastor, Pau (2)
Perneczky, Robert (2)
Hjermind, Lena E (2)
Nielsen, Jørgen E (2)
Rossi, Giacomina (2)
Boeve, Bradley F (2)
Rosen, Howard (2)
Huey, Edward D. (2)
Petersen, Ronald C. (2)
Benussi, Luisa (2)
Ghidoni, Roberta (2)
Binetti, Giuliano (2)
Seelaar, Harro (2)
Hofius, Daniel (2)
Minina, Alyona (2)
Hernandez, Dena G (2)
St George-Hyslop, Pe ... (2)
Graff-Radford, Neill ... (2)
Halliday, Glenda M (2)
Dickson, Dennis W (2)
Danek, Adrian (2)
Sorbi, Sandro (2)
Rowe, James B. (2)
Negoita, F. (2)
van Deerlin, Viviann ... (2)
Ruiz, Agustín (2)
Kristiansen, Mark (2)
Riemenschneider, Mat ... (2)
Morris, Huw R (2)
visa färre...
Lärosäte
Lunds universitet  (5)Ta bort avgränsningen
Karolinska Institutet (3)
Umeå universitet (2)
Stockholms universitet (2)
Linköpings universitet (2)
Sveriges Lantbruksuniversitet (2)
Språk
Engelska (5)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (4)
Naturvetenskap (3)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy