| 1. |
- Bromfield, Karen M., 1976, et al.
(author)
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An iron carbonyl approach to the influenza neuraminidase inhibitor oseltamivir
- 2007
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In: Chemical Communications. - : Royal Society of Chemistry (RSC). - 1364-548X .- 1359-7345. ; :30, s. 3183-3185
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Journal article (peer-reviewed)abstract
- A novel synthetic route towards oseltamivir, an influenza neuraminidase inhibitor, has been achieved employing a cationic iron carbonyl complex, providing an alternate pathway with the potential to access diverse analogues.
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| 2. |
- Eriksson, Jonas, et al.
(author)
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Solid supported active esters as linkers: modification of reactivity using iron carbonyl complexes
- 2006
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In: Tetrahedron Letters. - : Elsevier BV. - 0040-4039 .- 1873-3581. ; 47:5, s. 635-638
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Journal article (peer-reviewed)abstract
- The reactivity of three polymer-bound cyclohexadienoic acid active esters was modified by complexation with iron tricarbonyl in order to evaluate their potential use as linker systems for solid phase chemistry. The best results were obtained with the tetrallnorophenolester, which was slowly cleaved when 1 equiv of amine was used, but could be rapidly cleaved with up to 94% yield when the amount of nucleophile was increased. (c) 2005 Elsevier Ltd. All rights reserved.
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| 3. |
- Gradén, Henrik, 1968, et al.
(author)
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Carbon-carbon and carbon-heteroatom bond formation on solid phase using cationic iron carbonyl complexes
- 2005
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In: Organic Letters. - : American Chemical Society (ACS). - 1523-7052 .- 1523-7060. ; 7:16, s. 3565-3567
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Journal article (peer-reviewed)abstract
- Iron-mediated methodology for the formation of carbon-carbon and carbon-heteroatom sp(3) bonds on solid phase has been developed. Treatment of a polymer-bound cationic iron cyclohexadienyl complex with carbon, oxygen, nitrogen, and phosphorus nucleophiles, followed by cleavage with amines and subsequent decomplexation, yielded 18 different cyclohexadienoic acid amides of high purity.
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