↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Pedersen NL) ;pers:(Kaprio J)"

Sökning: WFRF:(Pedersen NL) > Kaprio J

Resultat 1-10 av 48

Sortera/gruppera träfflistan

Sortering: Träffar per sida:

Numrering	Referens	Omslagsbild	Hitta
1.	Dupuis, J, et al. (författare) New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk 2010 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 42:2, s. 105-U32 Tidskriftsartikel (refereegranskat)
2.	Manning, AK, et al. (författare) A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance 2012 Ingår i: Nature genetics. - New York : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 44:6, s. 659-U81 Tidskriftsartikel (refereegranskat)
3.	Graham, SE, et al. (författare) Author Correction: The power of genetic diversity in genome-wide association studies of lipids 2023 Ingår i: Nature. - 1476-4687. ; 618:7965, s. E19-E20 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
4.	Graham, SE, et al. (författare) The power of genetic diversity in genome-wide association studies of lipids 2021 Ingår i: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 600:7890, s. 675- Tidskriftsartikel (refereegranskat)
5.	Randall, JC, et al. (författare) Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits 2013 Ingår i: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404 .- 1553-7390. ; 9:6, s. e1003500- Tidskriftsartikel (refereegranskat)
6.	Wood, AR, et al. (författare) Defining the role of common variation in the genomic and biological architecture of adult human height 2014 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 46:11, s. 1173-1186 Tidskriftsartikel (refereegranskat)
7.	Billings, LK, et al. (författare) Impact of common variation in bone-related genes on type 2 diabetes and related traits 2012 Ingår i: Diabetes. - : American Diabetes Association. - 1939-327X .- 0012-1797. ; 61:8, s. 2176-2186 Tidskriftsartikel (refereegranskat)abstract Exploring genetic pleiotropy can provide clues to a mechanism underlying the observed epidemiological association between type 2 diabetes and heightened fracture risk. We examined genetic variants associated with bone mineral density (BMD) for association with type 2 diabetes and glycemic traits in large well-phenotyped and -genotyped consortia. We undertook follow-up analysis in ∼19,000 individuals and assessed gene expression. We queried single nucleotide polymorphisms (SNPs) associated with BMD at levels of genome-wide significance, variants in linkage disequilibrium (r2 > 0.5), and BMD candidate genes. SNP rs6867040, at the ITGA1 locus, was associated with a 0.0166 mmol/L (0.004) increase in fasting glucose per C allele in the combined analysis. Genetic variants in the ITGA1 locus were associated with its expression in the liver but not in adipose tissue. ITGA1 variants appeared among the top loci associated with type 2 diabetes, fasting insulin, β-cell function by homeostasis model assessment, and 2-h post–oral glucose tolerance test glucose and insulin levels. ITGA1 has demonstrated genetic pleiotropy in prior studies, and its suggested role in liver fibrosis, insulin secretion, and bone healing lends credence to its contribution to both osteoporosis and type 2 diabetes. These findings further underscore the link between skeletal and glucose metabolism and highlight a locus to direct future investigations.
8.	Bogl, LH, et al. (författare) Does the sex of one's co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts 2017 Ingår i: Biology of sex differences. - : Springer Science and Business Media LLC. - 2042-6410. ; 8, s. 14- Tidskriftsartikel (refereegranskat)
9.	Brumpton, B, et al. (författare) Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses 2020 Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 11:1, s. 3519- Tidskriftsartikel (refereegranskat)abstract Estimates from Mendelian randomization studies of unrelated individuals can be biased due to uncontrolled confounding from familial effects. Here we describe methods for within-family Mendelian randomization analyses and use simulation studies to show that family-based analyses can reduce such biases. We illustrate empirically how familial effects can affect estimates using data from 61,008 siblings from the Nord-Trøndelag Health Study and UK Biobank and replicated our findings using 222,368 siblings from 23andMe. Both Mendelian randomization estimates using unrelated individuals and within family methods reproduced established effects of lower BMI reducing risk of diabetes and high blood pressure. However, while Mendelian randomization estimates from samples of unrelated individuals suggested that taller height and lower BMI increase educational attainment, these effects were strongly attenuated in within-family Mendelian randomization analyses. Our findings indicate the necessity of controlling for population structure and familial effects in Mendelian randomization studies.
10.	Codd, V, et al. (författare) Identification of seven loci affecting mean telomere length and their association with disease 2013 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 45:4, s. 422-427 Tidskriftsartikel (refereegranskat)

Skapa referenser, mejla, bekava och länka

Länka till träfflistan

Resultat 1-10 av 48

Avgränsa träffmängd

Typ av publikation: tidskriftsartikel (43); konferensbidrag (5)

Typ av innehåll: refereegranskat (39); övrigt vetenskapligt/konstnärligt (9)

Författare/redaktör: Kaprio, J (48)Ta bort avgränsningen; Pedersen, NL (48); Martin, NG (32); Boomsma, DI (27); Magnusson, PKE (24); Willemsen, G (19); visa fler...; Spector, TD (19); Hottenga, JJ (16); Montgomery, GW (16); Medland, SE (16); van Duijn, CM (15); Christensen, K (15); Hayward, C. (15); Amin, N (14); Lehtimaki, T. (14); Jarvelin, MR (14); Campbell, H (13); Wilson, JF (13); Silventoinen, K (12); De Geus, EJC (12); Eriksson, JG (12); Gieger, C (12); McGue, M (12); Polašek, O. (12); Rudan, I. (12); Smith, GD (11); Lahti, J (11); Raikkonen, K. (11); Esko, T (11); Metspalu, A (11); Perola, M. (11); Heath, AC (11); Loos, RJF (10); Kumari, M (10); Stefansson, K (10); Widen, E (10); Tanaka, T. (9); Bartels, M (9); Ferrucci, L (9); Gudnason, V (9); Hofman, A (9); Uitterlinden, AG (9); Timpson, NJ (9); Sorensen, TIA (9); Snieder, H. (9); Palotie, A (9); Skytthe, A (9); Thorleifsson, G (9); Salomaa, V (9); Mihailov, E (9); visa färre...

Lärosäte: Karolinska Institutet (48); Uppsala universitet (7); Lunds universitet (5); Göteborgs universitet (4); Umeå universitet (4); Örebro universitet (3); visa fler...; Handelshögskolan i Stockholm (2); Stockholms universitet (1); Jönköping University (1); Högskolan i Skövde (1); Högskolan Dalarna (1); visa färre...

Språk: Engelska (48)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (10); Naturvetenskap (2)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - Nationella bibliotekssystem
LIBRIS.kb.se

pil uppåt

Stäng

Kopiera och spara länken för att återkomma till aktuell vy