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Natural-Cause Mortality and Long-Term Exposure to Particle Components : An Analysis of 19 European Cohorts within the Multi-Center ESCAPE Project
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Beelen, Rob (author)
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Hoek, Gerard (author)
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Raaschou-Nielsen, Ole (author)
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show more...
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Stafoggia, Massimo (author)
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Andersen, Zorana Jovanovic (author)
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Weinmayr, Gudrun (author)
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Hoffmann, Barbara (author)
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Wolf, Kathrin (author)
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Samoli, Evangelia (author)
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Fischer, Paul H. (author)
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Nieuwenhuijsen, Mark J. (author)
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Xun, Wei W. (author)
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Katsouyanni, Klea (author)
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Dimakopoulou, Konstantina (author)
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Marcon, Alessandro (author)
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Vartiainen, Erkki (author)
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Lanki, Timo (author)
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Yli-Tuomi, Tarja (author)
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Oftedal, Bente (author)
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Schwarze, Per E. (author)
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Nafstad, Per (author)
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- De Faire, Ulf (author)
- Karolinska Institutet
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- Pedersen, Nancy L. (author)
- Karolinska Institutet
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Otstenson, Claes-Goran (author)
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- Fratiglioni, Laura (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
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Penell, Johanna (author)
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Korek, Michal (author)
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- Pershagen, Goran (author)
- Karolinska Institutet
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Eriksen, Kirsten Thorup (author)
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Overvad, Kim (author)
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Sorensen, Mette (author)
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Eeftens, Marloes (author)
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Peeters, Petra H. (author)
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Meliefste, Kees (author)
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Wang, Meng (author)
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Bueno-de-Mesquita, H. Bas (author)
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Sugiri, Dorothea (author)
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Kramer, Ursula (author)
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Heinrich, Joachim (author)
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de Hoogh, Kees (author)
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Key, Timothy (author)
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Peters, Annette (author)
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Hampel, Regina (author)
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Concin, Hans (author)
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Nagel, Gabriele (author)
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Jaensch, Andrea (author)
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Ineichen, Alex (author)
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Tsai, Ming-Yi (author)
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Schaffner, Emmanuel (author)
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Probst-Hensch, Nicole M. (author)
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Schindler, Christian (author)
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Ragettli, Martina S. (author)
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Vilier, Alice (author)
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Clavel-Chapelon, Francoise (author)
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Declercq, Christophe (author)
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Ricceri, Fulvio (author)
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Sacerdote, Carlotta (author)
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Galassi, Claudia (author)
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Migliore, Enrica (author)
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Ranzi, Andrea (author)
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Cesaroni, Giulia (author)
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Badaloni, Chiara (author)
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Forastiere, Francesco (author)
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Katsoulis, Michail (author)
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Trichopoulou, Antonia (author)
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Keuken, Menno (author)
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Jedynska, Aleksandra (author)
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Kooter, Ingeborg M. (author)
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Kukkonen, Jaakko (author)
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Sokhi, Ranjeet S. (author)
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Vineis, Paolo (author)
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Brunekreef, Bert (author)
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(creator_code:org_t)
- Environmental Health Perspectives, 2015
- 2015
- English.
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In: Journal of Environmental Health Perspectives. - : Environmental Health Perspectives. - 0091-6765 .- 1552-9924. ; 123:6, s. 525-533
- Related links:
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https://doi.org/10.1...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Subject headings
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- Background: Studies have shown associations between mortality and long-term exposure to particulate matter air pollution. Few cohort studies have estimated the effects of the elemental composition of particulate matter on mortality. Objectives: Our aim was to study the association between natural-cause mortality and long-term exposure to elemental components of particulate matter. Methods: Mortality and confounder data from 19 European cohort studies were used. Residential exposure to eight a priori-selected components of particulate matter ( PM) was characterized following a strictly standardized protocol. Annual average concentrations of copper, iron, potassium, nickel, sulfur, silicon, vanadium, and zinc within PM size fractions <= 2.5 mu m (PM2.5) and <= 10 mu m (PM10) were estimated using land-use regression models. Cohort-specific statistical analyses of the associations between mortality and air pollution were conducted using Cox proportional hazards models using a common protocol followed by meta-analysis. Results: The total study population consisted of 291,816 participants, of whom 25,466 died from a natural cause during follow-up (average time of follow-up, 14.3 years). Hazard ratios were positive for almost all elements and statistically significant for PM2.5 sulfur (1.14; 95% CI: 1.06, 1.23 per 200ng/m(3)). In a two-pollutant model, the association with PM2.5 sulfur was robust to adjustment for PM2.5 mass, whereas the association with PM2.5 mass was reduced. Conclusions: Long-term exposure to PM2.5 sulfur was associated with natural-cause mortality. This association was robust to adjustment for other pollutants and PM2.5.
Subject headings
- NATURVETENSKAP -- Geovetenskap och miljövetenskap (hsv//swe)
- NATURAL SCIENCES -- Earth and Related Environmental Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine (hsv//eng)
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- By the author/editor
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Beelen, Rob
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Hoek, Gerard
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Raaschou-Nielsen ...
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Stafoggia, Massi ...
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Andersen, Zorana ...
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Weinmayr, Gudrun
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show more...
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Hoffmann, Barbar ...
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Wolf, Kathrin
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Samoli, Evangeli ...
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Fischer, Paul H.
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Nieuwenhuijsen, ...
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Xun, Wei W.
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Katsouyanni, Kle ...
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Dimakopoulou, Ko ...
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Marcon, Alessand ...
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Vartiainen, Erkk ...
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Lanki, Timo
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Yli-Tuomi, Tarja
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Oftedal, Bente
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Schwarze, Per E.
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Nafstad, Per
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De Faire, Ulf
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Pedersen, Nancy ...
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Otstenson, Claes ...
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Fratiglioni, Lau ...
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Penell, Johanna
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Korek, Michal
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Pershagen, Goran
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Eriksen, Kirsten ...
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Overvad, Kim
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Sorensen, Mette
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Eeftens, Marloes
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Peeters, Petra H ...
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Meliefste, Kees
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Wang, Meng
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Bueno-de-Mesquit ...
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Sugiri, Dorothea
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Kramer, Ursula
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Heinrich, Joachi ...
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de Hoogh, Kees
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Key, Timothy
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Peters, Annette
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Hampel, Regina
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Concin, Hans
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Nagel, Gabriele
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Jaensch, Andrea
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Ineichen, Alex
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Tsai, Ming-Yi
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Schaffner, Emman ...
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Probst-Hensch, N ...
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Schindler, Chris ...
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Ragettli, Martin ...
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Vilier, Alice
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Clavel-Chapelon, ...
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Declercq, Christ ...
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Ricceri, Fulvio
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Sacerdote, Carlo ...
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Galassi, Claudia
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Migliore, Enrica
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Ranzi, Andrea
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Cesaroni, Giulia
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Badaloni, Chiara
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Forastiere, Fran ...
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Katsoulis, Micha ...
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Trichopoulou, An ...
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Keuken, Menno
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Jedynska, Aleksa ...
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Kooter, Ingeborg ...
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Kukkonen, Jaakko
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Sokhi, Ranjeet S ...
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Vineis, Paolo
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Brunekreef, Bert
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Earth and Relate ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
- Articles in the publication
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Journal of Envir ...
- By the university
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Stockholm University
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Karolinska Institutet