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Träfflista för sökning "WFRF:(Petzold Max 1973) ;srt2:(2010-2014);srt2:(2013);pers:(Ngasala Billy)"

Search: WFRF:(Petzold Max 1973) > (2010-2014) > (2013) > Ngasala Billy

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1.
  • Aydin-Schmidt, Berit, et al. (author)
  • Usefulness of Plasmodium falciparum-specific rapid diagnostic tests for assessment of parasite clearance and detection of recurrent infections after artemisinin-based combination therapy.
  • 2013
  • In: Malaria journal. - : Springer Science and Business Media LLC. - 1475-2875. ; 12:1
  • Journal article (peer-reviewed)abstract
    • Rapid diagnostic test (RDT) is an important tool for parasite-based malaria diagnosis. High specificity of RDTs to distinguish an active Plasmodium falciparum infection from residual antigens from a previous infection is crucial in endemic areas where residents are repeatedly exposed to malaria. The efficiency of two RDTs based on histidine-rich protein 2 (HRP2) and lactate dehydrogenase (LDH) antigens were studied and compared with two microscopy techniques (Giemsa and acridine orange-stained blood smears) and real-time polymerase chain reaction (PCR) for assessment of initial clearance and detection of recurrent P. falciparum infections after artemisinin-based combination therapy (ACT) in a moderately high endemic area of rural Tanzania.
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2.
  • Malmberg, Maja, et al. (author)
  • Temporal trends of molecular markers associated with artemether-lumefantrine tolerance/resistance in Bagamoyo district, Tanzania.
  • 2013
  • In: Malaria journal. - : Springer Science and Business Media LLC. - 1475-2875. ; 12
  • Journal article (peer-reviewed)abstract
    • Development and spread of Plasmodium falciparum resistance to artemisinin-based combination therapy (ACT) constitutes a major threat to recent global malaria control achievements. Surveillance of molecular markers could act as an early warning system of ACT-resistance before clinical treatment failures are apparent. The aim of this study was to analyse temporal trends of established genotypes associated with artemether-lumefantrine tolerance/resistance before and after its deployment as first-line treatment for uncomplicated malaria in Tanzania 2006.
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