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Sökning: WFRF:(Ragupathy K)

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1.
  • Glasbey, JC, et al. (författare)
  • 2021
  • swepub:Mat__t
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2.
  • Khatri, C, et al. (författare)
  • Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study
  • 2021
  • Ingår i: BMJ open. - : BMJ. - 2044-6055. ; 11:11, s. e050830-
  • Tidskriftsartikel (refereegranskat)abstract
    • Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis.SettingProspective, international, multicentre, observational cohort study.ParticipantsPatients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infection (either 7 days prior or 30-day postoperative).Primary outcome30-day mortality. Multivariate modelling was performed to identify factors associated with 30-day mortality.ResultsThis study reports included 1063 patients from 174 hospitals in 19 countries. Overall 30-day mortality was 29.4% (313/1063). In an adjusted model, 30-day mortality was associated with male gender (OR 2.29, 95% CI 1.68 to 3.13, p<0.001), age >80 years (OR 1.60, 95% CI 1.1 to 2.31, p=0.013), preoperative diagnosis of dementia (OR 1.57, 95% CI 1.15 to 2.16, p=0.005), kidney disease (OR 1.73, 95% CI 1.18 to 2.55, p=0.005) and congestive heart failure (OR 1.62, 95% CI 1.06 to 2.48, p=0.025). Mortality at 30 days was lower in patients with a preoperative diagnosis of SARS-CoV-2 (OR 0.6, 95% CI 0.6 (0.42 to 0.85), p=0.004). There was no difference in mortality in patients with an increase to delay in surgery (p=0.220) or type of anaesthetic given (p=0.787).ConclusionsPatients undergoing surgery for a proximal femoral fracture with a perioperative infection of SARS-CoV-2 have a high rate of mortality. This study would support the need for providing these patients with individualised medical and anaesthetic care, including medical optimisation before theatre. Careful preoperative counselling is needed for those with a proximal femoral fracture and SARS-CoV-2, especially those in the highest risk groups.Trial registration numberNCT04323644
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3.
  • Vengadesan, K., et al. (författare)
  • Electrochemical Fabrication of Nano-Structured Poly(dimethoxyaniline)-Platinum Hybrid Materials: An Efficient Anode Electrocatalyst for Oxidation of Methanol
  • 2023
  • Ingår i: ES Energy and Environment. - : Engineered Science Publisher. - 2578-0646 .- 2578-0654. ; 19
  • Tidskriftsartikel (refereegranskat)abstract
    • A novel electro-co-deposited nanostructured poly(2,5 dimethoxyaniline) and Platinum (PDMA-Pt) nanocomposite were synthesized via single-step co-deposition by electrochemical method. The as-prepared nanocomposite material Methanol oxidation reaction Morphology was characterized through FESEM. PDMA-Pt shows an average diameter of 150-200 nm. The elemental percentage of PDMA-Pt was analyzed through EDX and mapping images. It shows that carbon, hydrogen, platinum, and oxygen are present in them. Physiochemical properties were characterized by XRD and FT-IR studies. XRD studies show the synthesized material is crystalline in nature. The electrochemical activity of the PDMA-Pt nanocomposite was observed using Cyclic voltammetry (CV), chronoamperometry (CA), and Electrochemical Impedance spectroscopic (EIS) techniques. The Electro-co-deposited PDMA-Pt modified electrode has efficient electrocatalytic activity with lower oxidation potential at 0.87 V and the Methanol oxidation reaction (MOR) stable time is 1500 s in 0.5 M H2SO4 acidic medium. The fabricated PDMA-Pt nanocomposite is capable of an anodic catalyst for direct methanol fuel cell utilization.
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