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- Glasbey, JC, et al.
(författare)
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- 2021
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swepub:Mat__t
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- Jahnke, Marlene, et al.
(författare)
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Potential and realized connectivity of the seagrass Posidonia oceanica and their implication for conservation
- 2017
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Ingår i: Diversity and Distributions. - : Wiley. - 1366-9516. ; 23:12, s. 1423-1434
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Tidskriftsartikel (refereegranskat)abstract
- Aim: Connectivity assessments are crucial to large-scale conservation planning, in particular for establishing and monitoring connected networks of marine protected areas (MPAs). Using biophysical modelling and genetic analyses, we assessed potential and realized connectivity among MPA populations of a benthic foundation species, the Mediterranean endemic seagrass Posidonia oceanica. Methods: We assessed potential and realized connectivity among eight P.oceanica meadows, mostly located in MPAs. Potential connectivity was assessed over a time horizon of 10years via an individual-based biophysical model whose physical component relies on fine-scale spatio-temporal ocean circulation fields. Genetic assessments of realized connectivity were carried out by means of a set of 14 neutral microsatellite loci, as well as a larger dataset of 19 loci including outlier loci that did not conform to expectations under neutrality. Results: Our findings point out a relatively high potential connectivity through long-range dispersal of floating fruits. Genetic connectivity analyses show a complex scenario with an apparent lower realized connectivity. The P.oceanica meadow within Torre Guaceto MPA (TOG), a well-enforced MPA within our study area, showed one of the highest levels of genotypic richness, indicative of high levels of sexual reproduction and/or recruitment of foreign genotypes. Both biophysical modelling and population genetics indicate that TOG is important to ensure the viability of the species at the local scale, and does likely play a key role as a source of propagules for the whole Adriatic area. Main conclusions: Our results show that realized dispersal does not necessarily match with the potential for dispersal. Still, both genetic and physical connectivity analyses show good agreement in identifying hotspots of connectivity. Such information can guide management of networks of MPAs and advance conservation of marine biodiversity.
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- Mineo Bianchi, F, et al.
(författare)
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Posterior muscle-fascial reconstruction and knotless urethro-neo bladder anastomosis during robot-assisted radical cystectomy: Description of the technique and its impact on urinary continence
- 2019
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Ingår i: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica. - : PAGEPress Publications. - 2282-4197. ; 91:1, s. 5-10
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of our study is to describe the use of posterior muscle-fascial reconstruction during urethro-ileal anastomosis in bladder cancer (BC) patients submitted to robot-assisted radical cystectomy (RC) with orthotopic neobladder (ON) and its role in facilitating day- and night-time continence recovery during a 12-month follow up. Materials and methods: We prospectively collected data from 42 consecutive patients who underwent RARC with totally intracorporeal ON and extended pelvic lymph node dissection (PLND) at our Institution from June 2014 to October 2017. Prior to the urethro-neobladder anastomosis we reconstructed the Denonvilliers Fascia (DF) as previously described for radical prostatectomy using a bidirectional barbed suture. Day and night-time recovery rates were reported at 3, 6 and 12 months after surgery, with continent patients being those using either no urinary pads or 1 safety pads. Results: Median age at surgery was 63 yrs, 41 (97.6%) patients were male. 28 (66.7%) patients presented a clinical T2 disease. Median operative time and median ON reconstruction time were 450 minutes and 180 minutes respectively. 13 (31%) individuals had non-organ confined disease, with 11 (26.2%) patients with positive lymph nodes (median 3 positive lymph nodes) and 2 (4.8%) with non-urothelial cancer at final pathologic examination. Median hospital stay and median catheterization time were 7 (IQR 7-8) and 21 (IQR 19-22). During first 30 post-operative days we recorded 7 (16.7%) low-grade Clavien and 2 (4.8%) IIIa Clavien complications, whereas between 30 and 90 postoperative days we recorded 4 (9.5%) low-grade, 4 (9.5) IIIa and 1 (2.4%) IIIb complications. Day-time and night-time continence rates were 61.9% vs 52.4%, 73.8% vs 64.3% and 90.5% vs 73.8% at three, six and twelve months follow up. Day-time continence was significantly superior in the younger group (97% vs 57%, p 0.01); night-time continence rates were also superior among < 70 yrs patients, despite not reaching statistical significance (77% vs 57%, p 0.3). Conclusions: Posterior muscle-fascial reconstruction aids continence recovery in BC patients undergoing RARC with ON, with younger and fitter patients most benefitting from ON reconstruction.
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