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Sökning: WFRF:(Sester M)

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  • Cossarizza, A., et al. (författare)
  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
  • 2019
  • Ingår i: European Journal of Immunology. - : Wiley. - 0014-2980 .- 1521-4141. ; 49:10, s. 1457-1973
  • Tidskriftsartikel (refereegranskat)abstract
    • These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often undermine immunological data. Notably, there are comprehensive sections of all major immune cell types with helpful Tables detailing phenotypes in murine and human cells. The latest flow cytometry techniques and applications are also described, featuring examples of the data that can be generated and, importantly, how the data can be analysed. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid, all written and peer-reviewed by leading experts in the field, making this an essential research companion.
  • Banabic, D., et al. (författare)
  • Sheet metal forming processes: Constitutive modelling and numerical simulation
  • 2010
  • Bok (övrigt vetenskapligt)abstract
    • The book gives a synthetic presentation of the research performed in the field of sheet metal forming simulation during more than twenty years by the members of three teams: the Research Centre on Sheet Metal Forming-CERTETA (Technical University of Cluj-Napoca, Romania); AUTOFORM software-house company from Zürich, Switzerland and VOLVO automotive company from Sweden. The first chapter reminds some fundamental topics of the theory of plasticity. A more extended chapter is devoted to the presentation of the phenomenological yield criteria, emphasizing the formulations proposed by the CERTETA team (BBC models). The sheet metal formability is discussed in a separate chapter. After presenting the methods used for the formability assessment, the discussion focuses on the forming limit curves. In this context, the authors emphasize their contributions to the mathematical modeling of forming limit curves. The aspects related to the implementation of the constitutive models in finite-element codes are discussed in the last chapter of the book. The performances of the models are proved by the numerical simulation of various sheet metal forming processes: hydroforming, deep-drawing and forming of the complex parts. The book is useful for the students, doctoral fellows, researchers and engineers who are mainly interested in the mechanical modeling and numerical simulation of sheet metal forming processes.
  • Lange, C, et al. (författare)
  • Clinical Application of Interferon-γ Release Assays for the Prevention of Tuberculosis in Countries with Low Incidence
  • 2016
  • Ingår i: Pathogens & immunity. - : Case Western Reserve University. - 2469-2964. ; 1:2, s. 308-329
  • Tidskriftsartikel (refereegranskat)abstract
    • Despite global efforts to control tuberculosis (TB) the estimated number of people who developed TB worldwide increased to an all-time record of more than 10 million in 2015. The goal of the World Health Organization (WHO) to reduce the global incidence of TB to less than 100 cases per million by 2035, cannot be reached unless TB prevention is markedly improved. There is a need for an improved vaccine that better protects individuals who are exposed to Mycobacterium tuberculosis from infection and active disease compared to the current M. bovis Bacille Calmette Guérin (BCG) vaccine. In the absence of such a vaccine, prevention relies on infection control measures and preventive chemotherapy for people with latent infection with M. tuberculosis (LTBI), who have the highest risk of progression to active TB. During the past decade, interferon-γ release assays (IGRAs) have increasingly replaced the tuberculin skin test as screening tools for the diagnosis of LTBI in countries with a low incidence of TB. Despite recent WHO guidelines on the management of LTBI, the definition of groups at risk for TB remains controversial, and the role of IGRAs for TB prevention in low-incidence countries remains uncertain. We reviewed the scientific literature and provide recommendations for the use of IGRAs for LTBI diagnosis in low-incidence countries. These recommendations are based on the number of patients needing treatment in order to prevent one case of TB. As the positive predictive value of IGRAs for the development of TB is sub-optimal, research must focus on the identification of alternative biomarkers that offer better predictive ability in order to substantially reduce the number needing treatment while improving the prevention of TB and improving the effectiveness of targeted preventive chemotherapy.
  • Sester, M, et al. (författare)
  • Numbers needed to treat to prevent tuberculosis
  • 2015
  • Ingår i: The European respiratory journal. - : European Respiratory Society (ERS). - 1399-3003 .- 0903-1936. ; 46:6, s. 1836-1838
  • Tidskriftsartikel (övrigt vetenskapligt)
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