| 1. |
- Lind, Monica, et al.
(författare)
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The dioxin-like pollutant PCB 126 (3,3',4,4',5-pentachlorobiphenyl) affects risk factors for cardiovascular disease in female rats
- 2004
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Ingår i: Toxicology Letters. - : Elsevier BV. - 0378-4274 .- 1879-3169. ; 150:3, s. 293-299
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Tidskriftsartikel (refereegranskat)abstract
- Epidemiological studies suggest that exposure to persistent organic pollutants such as organochlorines might induce cardiovascular disorders and diabetes. Some of these organochlorines, such as dioxins and some dioxin-like PCBs, have been characterised as anti-estrogenic due to their inhibition of estrogenic-induced responses. In the present pilot study, 40 female rats were subjected to either exposure to the dioxin-like 3,3',4,4',5-pentachlorobiphenyl (PCB 126) or vehicle, as well as ovariectomy (OVX) or sham operation in a 2 x 2 factorial design over 12 weeks to explore potential interactions between estrogen status and PCB 126 exposure on cardiovascular risk factors. PCB 126 increased heart weight and serum cholesterol levels in both groups. PCB 126 increased blood pressure in the sham-operated animals only. In conclusion, PCB 126 exposure in female rats resulted in effects on cardiovascular risk factors, such as serum cholesterol, blood pressure, and heart weight. Of these effects of PCB 126, the increase in blood pressure was dependent on estrogen status.
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| 2. |
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| 3. |
- Sundin, Peter, et al.
(författare)
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International Science Programme : Annual Report for 2009
- 2010
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Rapport (populärvet., debatt m.m.)abstract
- ISP provides long-term support for the development of active and sustainable research environments within these basic sciences in developing countries. The support is directed to research groups and regional networks. The work is carried out in close cooperation with research groups at more advanced host institutions. Although Uppsala University is the base of the operation, ISP functions as a national programme and host laboratories may be at other Swedish universities, in other Nordic and European countries, and in the regions. This is to meet the requests from developing countries on their own terms.ISP funding is used for equipment, spare parts, consumables, technical services, literature, computer hard- and software, and costs associated with arranging and participating in meetings, exchange visits, training, etc. Besides what has been achieved in terms of development and maintenance of resources, contacts, etc., the results of ISP support in 2009 can be summarized based on the expenditures. For each MEUR spent (assuming that one EUR equals 10 SEK) the outcome was:19 PhD graduations,59 MSc/MPhil graduations,45 international publications,58 regional or national publicationst,113 conference contributions (34% of which international), and20 conferences/workshops etc. arranged.
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| 4. |
- Sundin, Peter, et al.
(författare)
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International Science Programme : Annual Report for 2008
- 2009
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Rapport (populärvet., debatt m.m.)abstract
- ISP provides long-term support for the development of active and sustainable research environments within these basic sciences in developing countries. The support is directed to research groups and regional networks. The work is carried out in close cooperation with research groups at more advanced host institutions. Although Uppsala Univ. is the base of the operation, ISP functions as a national programme and host laboratories may be located at other Swedish universities, in other Nordic and European countries, and in the regions. This is to meet the requests from developing countries on their own terms.ISP support includes equipment, spare parts consumables, technical services, literature, computer hard- and software, and all costs associated with participating in meetings, exchange visits, training, etc. Besides what has been achieved in terms of development and maintenance of resources, contacts, etc., the outcome of ISP support in 2008 can be summarized by the following figures (assuming that one € equals 10 SEK):19 PhD graduations per M€ invested.54 MSc/MPhil graduations per M€ invested.80 international publications per M€ invested.27 regional or national publications per M€ invested.129 conference contributions (> 40% of which international) per M€ invested.
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| 5. |
- Söderberg, Daniel, et al.
(författare)
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Individual Patient Factors Associated with the Use of Physical or Digital Primary Care in Sweden
- 2024
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Ingår i: Telemedicine journal and e-health. - : Mary Ann Liebert, Inc., publishers. - 1530-5627 .- 1556-3669.
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: Little is known about factors that influence patients' choice to use physical or digital primary care. This study aimed to compare self-rated health, internet habits, and what patients deem important when choosing health care between users of physical and digital primary health care. Methods: We recruited 2,716 adults visiting one of six physical or four digital primary health care providers in Stockholm, Sweden, October 2020 to May 2021. Participants answered a questionnaire with questions about sociodemography, self-rated health, internet habits, and what they considered important when seeking care. We used logistic regression and estimated odds ratios (ORs) for choosing digital care. Results: Digital users considered themselves healthier and used the internet more, compared with physical users (p < 0.001). Competence of health care staff was the most important factor when seeking care to both physical and digital users (90% and 78%, respectively). Patients considering it important to avoid leaving home were more likely to seek digital care (OR 29.55, 95% confidence interval [CI] 12.65?69.06), while patients valuing continuity were more likely to seek physical care (OR 0.25, 95% CI 0.19?0.32). These factors were significant also when adjusting for self-rated health and sociodemographic characteristics. Conclusion: What patients considered important when seeking health care was associated with what type of care they sought. Patient preferences should be considered when planning health care to optimize resource allocation.
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