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- Jahnson, S., et al.
(författare)
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Thromboembolism in Muscle-Invasive Bladder Cancer. A Population-based Nationwide Study
- 2021
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Ingår i: Bladder Cancer. - : IOS Press. - 2352-3727 .- 2352-3735. ; 7:2, s. 161-171
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Routine VTE prophylaxis within 30 days of radical cystectomy (RC) for urinary bladder cancer (UBC) is used to protect from venous thromboembolism (VTE). However, randomized studies and nationwide population-based studies are lacking. OBJECTIVE: To study VTE and risk factors for VTE in muscle-invasive UBC in a nationwide population-based series, with a focus on the association with RC with and without chemotherapy. MATERIALS AND METHODS: We studied all patients with clinical stage T2-T4 UBC diagnosed 1997 to 2014 in the Bladder Cancer Data Base Sweden (BladderBaSe). Previous VTE events and risk factors for VTE were registered from 1987. Cox regression analyses and Kaplan-Meier curves were performed to study risk factors for VTE and cumulative incidence of VTE. RESULTS: In 9720 patients (71% males) with a median age of 74 years 546 (5.6%) had VTE after diagnosis. In Cox analyses controlling for patient's and tumour characteristics, and risk factors for VTE, VTE after diagnosis and first treatment date were associated with chemotherapy with or without RC. Cumulative incidence of VTE increased during 24 months after diagnosis and first treatment date. VTE were less common in patients with previous cardiovascular disease. CONCLUSION: VTE was commonly observed after 30 days from diagnosis and from first treatment date in patients with T2-T4 UBC, particularly after chemotherapy. The findings suggest that long-term intervention studies of benefit and possible harms of VTE prophylaxis after UBC should be undertaken.
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- Nystrom, L., et al.
(författare)
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A NOTE ON SOME IDENTIFICATION PROBLEMS ARISING IN ROENTGEN STEREO PHOTOGRAMMETRIC ANALYSIS
- 1994
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Ingår i: Journal of Biomechanics. ; 27:10, s. 1291-1294
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Tidskriftsartikel (refereegranskat)abstract
- When studying skeleton movements by using implanted landmarks and Roentgen stereo photogrammetric analysis (RSA), some identification problems arise. One is to put the same label on a landmark at different examinations, another is to use the correct pairs of landmark images in order to compute a correct three-dimensional position of each landmark. We will present some methods that can be used as a support for solving these problems. We will also show how it is possible to detect and exclude landmarks that are loose and landmarks that have large measurement errors in their positions.
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- Soderkvist, I., et al.
(författare)
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ON CONDITION NUMBERS AND ALGORITHMS FOR DETERMINING A RIGID-BODY MOVEMENT
- 1994
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Ingår i: Bit. ; 34:3, s. 424-436
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Tidskriftsartikel (refereegranskat)abstract
- Using a set of landmarks to represent a rigid body, a rotation of the body can be determined in least-squares sense as the solution of an orthogonal Procrustes problem. We discuss some geometrical properties of the condition number for the problem of determining the orthogonal matrix representing the rotation. It is shown that the condition number critically depends on the configuration of the landmarks. The problem is also reformulated as an unconstrained nonlinear least-squares problem and the condition number is related to the geometry of such problems. In the common 3-D case, the movement can be represented by using a screw axis. Also the condition numbers for the problem of determining the screw axis representation are shown to closely depend on the configuration of the landmarks. The condition numbers are finally used to show that the used algorithms are stable.
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