| 1. |
- Wang, J., et al.
(författare)
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Final report of the CCQM-K145 : Toxic and essential elements in bovine liver
- 2020
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Ingår i: Metrologia. - : IOP Publishing Ltd. - 0026-1394 .- 1681-7575. ; 57:1 A
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Tidskriftsartikel (refereegranskat)abstract
- Liver plays a major role in metabolism and acts as a source of energy for the body by storing glycogen. With the growing interest and investigation in the biological effects in recent years, it is important and necessary to develop accurate and comparable analytical methods for elements in bio-samples. It has, however, been 10 years since the tissue sample (bovine liver) of CCQM-K49 key comparison. The purpose of CCQM-K145 is to ensure the comparable and traceable measurement results for essential and toxic elements such as P, S, Zn, Mn, Ni, Mo, Sr, Cr, Co, Pb, As and Hg in bovine liver among NMIs and other designated measurement bodies worldwide. The comparison was agreed by IAWG as 6th IAWG Benchmarking Exercise with Zn and Ni as exemplary elements at the meeting in Korea in the early October 2016. The results of CCQM-K145 are expected to cover the measurement capability and support CMCs claiming for inorganic elements in the similar biological tissue materials and food samples. 30 NMIs and DIs registered in CCQM-K145. With respect to the methodology, a variety of techniques such as IDMS, ICP-OES, ICP-MS(non-ID), AAS and NAA were adopted by the participants. For Zn, Ni, Sr, Pb and Hg measurements, most participants chose ID-ICP-MS method, which showed the better performance in terms of consistency and reliability of the measurement results. In aspect of the traceability for the measurement results in CCQM-K145, most participants used their own (in house) CRMs or other NMI's CRMs to guarantee trace to SI unit. Most participants used similar matrix CRMs for quality control or method validation. Base on different statistic way to calculate the reference mass fraction values and associated uncertainties for each measurand, removal of the suspected extreme values, and discussion at the IAWG meetings, the median values are proposed as the KCRV for Zn, Ni, Mn, Mo, Cr, Pb and Hg; the arithmetic mean values are proposed as the KCRV for P, S, Sr, Co and As. In general, the performances of the majority of CCQM-K145 participants are very good, illustrating their measurement capabilities for Zn, Ni, P, S, Mn, Mo, Sr, Cr, As, Co, Pb and Hg in a complex biological tissue matrix. Bovine liver contains many kinds of nutrients and microelements, it can be regarded as a typical representative material of biological tissue and food. In CCQM-K145, the analytes involved alkali metals and transition elements, metalloids/semi-metals and non metals with a range of mass fraction from mg/g to μg/kg. CCQM-K145 also tested the ability of NMIs/DIs to determine elements that were easy to be lost and polluted, and interfered significantly. The chemical pretreatment methods of samples used in the comparison is suitable for general food and biological matrix samples. A variety of measurement methods used in the comparison represent the main instrumental technology for elemental analysis. Therefore, for supporting CMC claim, CCQM-K145 is readily applicable to measurement of more elements in a wide range of biological materials (including liquids and solids) and meat products. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
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| 2. |
- Park, D. -M, et al.
(författare)
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Comparative study on added resistance of a container ship in waves
- 2019
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Ingår i: Proceedings of the International Offshore and Polar Engineering Conference. - : International Society of Offshore and Polar Engineers. - 9781880653852 ; , s. 4418-4425
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Konferensbidrag (refereegranskat)abstract
- This paper presents a comparative study on the motion responses and added resistance of a container ship. Eight institutions participated in the comparative study, and ten numerical results were compared with two experimental results. Two experimental results were obtained from Seoul National University towing tank and Sweden SSPA seakeeping basin. The results of two experimental institutions in head sea condition were compared and showed good agreement with each other. The difference in motion responses and added resistance according to the numerical analysis method were compared. Even though the same program was used, it was observed that different results were obtained depending on the users. The comparison of the motion response and the added resistance according to the change of wave slope showed that the added resistance greatly changed according to the wave slope. This tendency was the same in experimental results and CFD analysis results. From the comparative study, the influence of the experiment method on the added resistance, and the characteristics of numerical each code were identified.
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| 3. |
- Lee, Jookyeong, et al.
(författare)
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Terpyridine-functionalized stimuli-responsive microgels and their assembly through metal-ligand interactions
- 2018
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Ingår i: Polymer Chemistry. - : Royal Society of Chemistry (RSC). - 1759-9954 .- 1759-9962. ; 9:8, s. 1032-1039
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Tidskriftsartikel (refereegranskat)abstract
- We developed a terpyridine-functionalized microgel (tpy-mG) for its supramolecular assembly. Tpy-mG was synthesized by amidation between 3-(4-([2,2′:6′,2′′-terpyridin]-4′-yl)phenoxy)propan-1-amine and carboxylates of a thermo-responsive p(NIPAM-co-MAA) microgel (A-mG), which was synthesized by emulsion polymerization. After decorating terpyridine, its effects on the hydrodynamic radius, volume phase transition temperature (VPTT), and the colloidal stability of the microgel were investigated. Tpy-mG can be assembled reversibly with several metal ions (Ni2+, Fe2+, Co2+, or Zn2+), and interestingly the assembled tpy-mG-M2+ showed different rheological properties depending on the metal ion type; the weakly bound ions (Co2+, Zn2+) indicated fast dynamics for "inter-particular" exchange, resulting in much higher storage (G′) and loss (G′′) moduli. Photocatalysts such as Ru dyes can be easily introduced into tpy-mGvia metal-ligand interactions, and the photooxidation of benzylamine was tested. The free Ru dye showed almost the same conversions at 25 and 50 °C, whereas the assembled Ru-tpy-mG-Mg2+ displayed reduced conversion at 50 °C (>VPTT). This is suggested to be due to the collapsed or "locked" structure around the photocatalytic center (Ru). Tpy-mG can be utilized as a good platform for developing responsive functional materials via reversible metal-ligand complexation.
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| 4. |
- Park, M. S., et al.
(författare)
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InAs/GaAs p-i-p quantum dots-in-a-well infrared photodetectors operating beyond 200 K
- 2014
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Ingår i: Electronics Letters. - Stevenage, United Kingdom : Institution of Engineering and Technology (IET). - 1350-911X .- 0013-5194. ; 50:23, s. 1731-1732
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Tidskriftsartikel (refereegranskat)abstract
- High-temperature operating performance of p-i-p quantum dots-in-awell infrared photodetectors (QDIPs) is successfully demonstrated. The optically active region consists of 10 layers of p-doped selfassembled InAs quantum dots (QDs) asymmetrically positioned in In0.15Ga0.85As quantum wells (QWs). The dark current is suppressed by an incorporated superlattice (SL) structure composed of 10 pairs of AlGaAs/GaAs heterostructure. The very low recorded dark current makes the fabricated p-i-p QDIPs suitable for high-temperature operation. The measured photoresponse reveals broad mid-wave infrared (MWIR) detection up to 200 K.
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| 5. |
- Pignatelli, Francesco, et al.
(författare)
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Effect of CO2 dilution on structures of premixed syngas/air flames in a gas turbine model combustor
- 2023
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Ingår i: Combustion and Flame. - : Elsevier Inc.. - 0010-2180 .- 1556-2921. ; 255
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Tidskriftsartikel (refereegranskat)abstract
- The impact of CO2 dilution on combustion of syngas (a mixture of H2, CO, and CH4) was investigated in a lab-scale gas turbine model combustor at atmospheric pressure conditions. Two mild dilution levels of CO2, corresponding to 15% and 34% of CO2 mole fraction in the syngas/CO2 mixtures, were experimentally investigated to evaluate the effects of CO2 dilution on the flame structures and the emissions of CO and NOx. All experiments were performed at a constant Reynolds number (Re = 10000). High-speed flame luminescence, simultaneous planar laser-induced fluorescence (PLIF) measurements of the OH radicals and particle image velocimetry (PIV) were employed for qualitative and quantitative assessment of the resulting flame and flow structures. The main findings are: (a) the operability range of the syngas flames is significantly affected by the CO2 dilution, with both the lean blowoff (LBO) limit and the flashback limit shifting towards fuel-richer conditions as the CO2 dilution increases; (b) syngas flames exhibit flame-pocket structures with chemical reactions taking place in isolated pockets surrounded by non-reacting fuel/air mixture; (c) the inner recirculation zone tends to move closer to the burner axis at high CO2 dilution, and (d) the NOx emission becomes significantly lower with increasing CO2 dilution while the CO emission exhibits the opposite trend. The flame-pocket structure is more significant with increased CO2 dilution level. The low NOx emissions and high CO emissions are the results of the flame-pocket structures. © 2023 The Author(s)
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| 6. |
- Tiemann, Tom T, et al.
(författare)
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Towards uterus tissue engineering: a comparative study of sheep uterus decellularisation
- 2020
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Ingår i: Molecular human reproduction. - : Oxford University Press (OUP). - 1460-2407 .- 1360-9947. ; 26:3, s. 167-178
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Tidskriftsartikel (refereegranskat)abstract
- © The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. Uterus tissue engineering may dismantle limitations in current uterus transplantation protocols. A uterine biomaterial populated with patient-derived cells could potentially serve as a graft to circumvent complicated surgery of live donors, immunosuppressive medication and rejection episodes. Repeated uterine bioengineering studies on rodents have shown promising results using decellularised scaffolds to restore fertility in a partially impaired uterus and now mandate experiments on larger and more human-like animal models. The aim of the presented studies was therefore to establish adequate protocols for scaffold generation and prepare for future in vivo sheep uterus bioengineering experiments. Three decellularisation protocols were developed using vascular perfusion through the uterine artery of whole sheep uteri obtained from slaughterhouse material. Decellularisation solutions used were based on 0.5% sodium dodecyl sulphate (Protocol 1) or 2% sodium deoxycholate (Protocol 2) or with a sequential perfusion of 2% sodium deoxycholate and 1% Triton X-100 (Protocol 3). The scaffolds were examined by histology, extracellular matrix quantification, evaluation of mechanical properties and the ability to support foetal sheep stem cells after recellularisation. We showed that a sheep uterus can successfully be decellularised while maintaining a high integrity of the extracellular components. Uteri perfused with sodium deoxycholate (Protocol 2) were the most favourable treatment in our study based on quantifications. However, all scaffolds supported stem cells for 2weeks in vitro and showed no cytotoxicity signs. Cells continued to express markers for proliferation and maintained their undifferentiated phenotype. Hence, this study reports three valuable decellularisation protocols for future in vivo sheep uterus bioengineering experiments.
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