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Objective Evaluation of Multiple Sclerosis Lesion Segmentation using a Data Management and Processing Infrastructure

Commowick, Olivier (author)
Univ Rennes 1, CNRS, INSERM, VISAGES,U1228,UMR6074, Rennes, France.
Istace, Audrey (author)
Hosp Civils Lyon, Lyon Sud Hosp, Dept Radiol, Lyon, France.
Kain, Michael (author)
Univ Rennes 1, CNRS, INSERM, VISAGES,U1228,UMR6074, Rennes, France.
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Laurent, Baptiste (author)
Univ Brest, IBSAM, INSERM, LaTIM,UMR 1101, Brest, France.
Leray, Florent (author)
Univ Rennes 1, CNRS, INSERM, VISAGES,U1228,UMR6074, Rennes, France.
Simon, Mathieu (author)
Univ Rennes 1, CNRS, INSERM, VISAGES,U1228,UMR6074, Rennes, France.
Pop, Sorina Camarasu (author)
Univ Claude Bernard Lyon 1, Univ Lyon,INSA Lyon, UJM St Etienne,CNRS,Inserm, CREATIS,UMR 5220,U1206, F-69621 Lyon, France.
Girard, Pascal (author)
Univ Claude Bernard Lyon 1, Univ Lyon,INSA Lyon, UJM St Etienne,CNRS,Inserm, CREATIS,UMR 5220,U1206, F-69621 Lyon, France.
Ameli, Roxana (author)
Hosp Civils Lyon, Lyon Sud Hosp, Dept Radiol, Lyon, France.
Ferre, Jean-Christophe (author)
Univ Rennes 1, CNRS, INSERM, VISAGES,U1228,UMR6074, Rennes, France.;CHU Rennes, Dept Neuroradiol, F-35033 Rennes, France.
Kerbrat, Anne (author)
Univ Rennes 1, CNRS, INSERM, VISAGES,U1228,UMR6074, Rennes, France.;CHU Rennes, Dept Neurol, F-35033 Rennes, France.
Tourdias, Thomas (author)
CHU Bordeaux, Serv Neuroimagerie, Bordeaux, France.
Cervenansky, Frederic (author)
Univ Claude Bernard Lyon 1, Univ Lyon,INSA Lyon, UJM St Etienne,CNRS,Inserm, CREATIS,UMR 5220,U1206, F-69621 Lyon, France.
Glatard, Tristan (author)
Concordia Univ, Dept Comp Sci & Software Engn, Montreal, PQ, Canada.
Beaumont, Jeremy (author)
Univ Rennes 1, CNRS, INSERM, VISAGES,U1228,UMR6074, Rennes, France.
Doyle, Senan (author)
Pixyl Med, Grenoble, France.
Forbes, Florence (author)
Pixyl Med, Grenoble, France.;Inria Grenoble Rhone Alpes, Grenoble, France.
Knight, Jesse (author)
Univ Guelph, Sch Engn, Image Anal Med Lab, Guelph, ON, Canada.
Khademi, April (author)
Ryerson Univ, Image Anal Med Lab IAMLAB, Toronto, ON, Canada.
Mahbod, Amirreza (author)
KTH,Skolan för teknik och hälsa (STH)
Wang, Chunliang, 1980- (author)
KTH,Skolan för teknik och hälsa (STH)
McKinley, Richard (author)
Univ Bern, Dept Diagnost & Intervent Neuroradiol, Inselspital, Bern, Switzerland.
Wagner, Franca (author)
Univ Bern, Dept Diagnost & Intervent Neuroradiol, Inselspital, Bern, Switzerland.
Muschelli, John (author)
Johns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA.
Sweeney, Elizabeth (author)
Johns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA.
Roura, Eloy (author)
Univ Girona, Res Inst Comp Vis & Robot VICOROB, Girona, Spain.
Llado, Xavier (author)
Univ Girona, Res Inst Comp Vis & Robot VICOROB, Girona, Spain.
Santos, Michel M. (author)
Univ Fed Pernambuco, Ctr Informat, Recife, Brazil.
Santos, Wellington P. (author)
Univ Fed Pernambuco, Dept Engn Biomed, Recife, Brazil.
Silva-Filho, Abel G. (author)
Univ Fed Pernambuco, Ctr Informat, Recife, Brazil.
Tomas-Fernandez, Xavier (author)
Childrens Hosp, Dept Radiol, Computat Radiol Lab, 300 Longwood Ave, Boston, MA 02115 USA.
Urien, Helene (author)
Univ Paris Saclay, LTCI, Telecom ParisTech, Paris, France.
Bloch, Isabelle (author)
Univ Paris Saclay, LTCI, Telecom ParisTech, Paris, France.
Valverde, Sergi (author)
Univ Girona, Res Inst Comp Vis & Robot VICOROB, Girona, Spain.
Cabezas, Mariano (author)
Univ Girona, Res Inst Comp Vis & Robot VICOROB, Girona, Spain.
Javier Vera-Olmos, Francisco (author)
Univ Rey Juan Carlos, Med Image Anal Lab, Madrid, Spain.
Malpica, Norberto (author)
Univ Rey Juan Carlos, Med Image Anal Lab, Madrid, Spain.
Guttmann, Charles (author)
Brigham & Womens Hosp, Dept Radiol, Ctr Neurol Imaging, 75 Francis St, Boston, MA 02115 USA.
Vukusic, Sandra (author)
Hosp Civils Lyon, Lyon Sud Hosp, Dept Radiol, Lyon, France.
Edan, Gilles (author)
Univ Rennes 1, CNRS, INSERM, VISAGES,U1228,UMR6074, Rennes, France.;CHU Rennes, Dept Neurol, F-35033 Rennes, France.
Dojat, Michel (author)
Univ Grenoble Alpes, CHU Grenoble, GIN, Inserm,U1216, Grenoble, France.
Styner, Martin (author)
Univ N Carolina, Dept Comp Sci, Chapel Hill, NC 27515 USA.
Warfield, Simon K. (author)
Childrens Hosp, Dept Radiol, Computat Radiol Lab, 300 Longwood Ave, Boston, MA 02115 USA.
Cotton, Francois (author)
Hosp Civils Lyon, Lyon Sud Hosp, Dept Radiol, Lyon, France.
Barillot, Christian (author)
Univ Rennes 1, CNRS, INSERM, VISAGES,U1228,UMR6074, Rennes, France.
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Univ Rennes 1, CNRS, INSERM, VISAGES,U1228,UMR6074, Rennes, France Hosp Civils Lyon, Lyon Sud Hosp, Dept Radiol, Lyon, France. (creator_code:org_t)
2018-09-12
2018
English.
In: Scientific Reports. - : Nature Publishing Group. - 2045-2322. ; 8
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • We present a study of multiple sclerosis segmentation algorithms conducted at the international MICCAI 2016 challenge. This challenge was operated using a new open-science computing infrastructure. This allowed for the automatic and independent evaluation of a large range of algorithms in a fair and completely automatic manner. This computing infrastructure was used to evaluate thirteen methods of MS lesions segmentation, exploring a broad range of state-of-theart algorithms, against a high-quality database of 53 MS cases coming from four centers following a common definition of the acquisition protocol. Each case was annotated manually by an unprecedented number of seven different experts. Results of the challenge highlighted that automatic algorithms, including the recent machine learning methods (random forests, deep learning,.), are still trailing human expertise on both detection and delineation criteria. In addition, we demonstrate that computing a statistically robust consensus of the algorithms performs closer to human expertise on one score (segmentation) although still trailing on detection scores.

Subject headings

TEKNIK OCH TEKNOLOGIER  -- Annan teknik (hsv//swe)
ENGINEERING AND TECHNOLOGY  -- Other Engineering and Technologies (hsv//eng)

Publication and Content Type

ref (subject category)
art (subject category)

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