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Sökning: WFRF:(Takahashi A) > Södertörns högskola

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1.
  • Korayem, A M, et al. (författare)
  • A Drosophila salivary gland mucin is also expressed in immune tissues : evidence for a function in coagulation and the entrapment of bacteria
  • 2004
  • Ingår i: Insect Biochemistry and Molecular Biology. - : Elsevier BV. - 0965-1748 .- 1879-0240. ; 34:12, s. 1297-1304
  • Tidskriftsartikel (refereegranskat)abstract
    • Our studies on the developmental regulation of glycosylation in Drosophila melanogaster led us to identify and characterize gp 150, an ecdysone-regulated mucin that is found in hemocytes, the gut (peritrophic membrane) and in the salivary glands. We are particularly interested in mucin immune functions and found that gp 150 is released from larval hemocytes, becomes part of the clot and participates in the entrapment of bacteria. By RT-PCR and RNAi experiments, we identified gp 150 as the previously described 171-7, an ecdysone-induced salivary glue protein. We discuss the evolutionary and biochemical implications of the dual use of salivary proteins for immune functions in insects. Further molecular characterization of such shared proteins may enable a better understanding of the properties of proteins involved in containment and elimination of microbes, as well as hemostasis and wound repair.
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2.
  • Saito, A., et al. (författare)
  • Association Between Autistic Traits in Preschool Children and Later Emotional/Behavioral Outcomes
  • 2017
  • Ingår i: Journal of autism and developmental disorders. - : Springer. - 0162-3257 .- 1573-3432. ; 47:11, s. 3333-3346
  • Tidskriftsartikel (refereegranskat)abstract
    • Although children with a greater number of autistic traits are likely to have other mental health problems, research on the association between earlier autistic traits in preschool children and later emotional/behavioral outcomes is scarce. Using data from 189 Japanese community-based children, this study examined whether autistic traits at age 5 were related to emotional/behavioral outcomes at age 7. The results showed that prior autistic traits were subsequently associated with all emotional/behavioral domains. After controlling for baseline emotional/behavioral scores autistic traits continued to predict later emotional symptoms and peer problems. This study highlights that in addition to clinical ASD, it is also important to focus on subthreshold autistic traits in preschool children for better subsequent emotional/behavioral outcomes.
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  • Resultat 1-2 av 2
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tidskriftsartikel (2)
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refereegranskat (2)
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Takahashi, K (1)
Takahashi, H. (1)
Saito, A. (1)
Stickley, Andrew (1)
Dushay, Mitchell S. (1)
Lindgren, Malin (1)
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Theopold, U (1)
Fabbri, M (1)
Schmidt, O (1)
Kamio, Y. (1)
Haraguchi, H. (1)
Ishitobi, M. (1)
Korayem, A. M. (1)
Scherfer, C. (1)
Ueda, R (1)
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Södertörns högskola  (2)Ta bort avgränsningen
Stockholms universitet (1)
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Engelska (2)
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Naturvetenskap (1)
Samhällsvetenskap (1)

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