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Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution

Hillier, Ladeana W (author)
Miller, Webb (author)
Birney, Ewan (author)
show more...
Warren, Wesley (author)
Hardison, Ross C (author)
Ponting, Chris P (author)
Bork, Peer (author)
Burt, David W (author)
Groenen, Martien A M (author)
Delany, Mary E (author)
Dodgson, Jerry B (author)
Chinwalla, Asif T (author)
Cliften, Paul F (author)
Clifton, Sandra W (author)
Delehaunty, Kimberly D (author)
Fronick, Catrina (author)
Fulton, Robert S (author)
Graves, Tina A (author)
Kremitzki, Colin (author)
Layman, Dan (author)
Magrini, Vincent (author)
McPherson, John D (author)
Miner, Tracie L (author)
Minx, Patrick (author)
Nash, William E (author)
Nhan, Michael N (author)
Nelson, Joanne O (author)
Oddy, Lachlan G (author)
Pohl, Craig S (author)
Randall-Maher, Jennifer (author)
Smith, Scott M (author)
Wallis, John W (author)
Yang, Shiaw-Pyng (author)
Romanov, Michael N (author)
Rondelli, Catherine M (author)
Paton, Bob (author)
Smith, Jacqueline (author)
Morrice, David (author)
Daniels, Laura (author)
Tempest, Helen G (author)
Robertson, Lindsay (author)
Masabanda, Julio S (author)
Griffin, Darren K (author)
Vignal, Alain (author)
Fillon, Valerie (author)
Jacobbson, Lina (author)
Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
Kerje, Susanne (author)
Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
Andersson, Leif (author)
Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
Crooijmans, Richard P M (author)
Aerts, Jan (author)
van der Poel, Jan J (author)
Ellegren, Hans (author)
Uppsala universitet,Institutionen för evolution, genomik och systematik,Evolutionsbiologi
Caldwell, Randolph B (author)
Hubbard, Simon J (author)
Grafham, Darren V (author)
Kierzek, Andrzej M (author)
McLaren, Stuart R (author)
Overton, Ian M (author)
Arakawa, Hiroshi (author)
Beattie, Kevin J (author)
Bezzubov, Yuri (author)
Boardman, Paul E (author)
Bonfield, James K (author)
Croning, Michael D R (author)
Davies, Robert M (author)
Francis, Matthew D (author)
Humphray, Sean J (author)
Scott, Carol E (author)
Taylor, Ruth G (author)
Tickle, Cheryll (author)
Brown, William R A (author)
Rogers, Jane (author)
Buerstedde, Jean-Marie (author)
Wilson, Stuart A (author)
Stubbs, Lisa (author)
Ovcharenko, Ivan (author)
Gordon, Laurie (author)
Lucas, Susan (author)
Miller, Marcia M (author)
Inoko, Hidetoshi (author)
Shiina, Takashi (author)
Kaufman, Jim (author)
Salomonsen, Jan (author)
Skjoedt, Karsten (author)
Wong, Gane Ka-Shu (author)
Wang, Jun (author)
Liu, Bin (author)
Wang, Jian (author)
Yu, Jun (author)
Yang, Huanming (author)
Nefedov, Mikhail (author)
Koriabine, Maxim (author)
Dejong, Pieter J (author)
Goodstadt, Leo (author)
Webber, Caleb (author)
Dickens, Nicholas J (author)
Letunic, Ivica (author)
Suyama, Mikita (author)
Torrents, David (author)
von Mering, Christian (author)
Zdobnov, Evgeny M (author)
Makova, Kateryna (author)
Nekrutenko, Anton (author)
Elnitski, Laura (author)
Eswara, Pallavi (author)
King, David C (author)
Yang, Shan (author)
Tyekucheva, Svitlana (author)
Radakrishnan, Anusha (author)
Harris, Robert S (author)
Chiaromonte, Francesca (author)
Taylor, James (author)
He, Jianbin (author)
Rijnkels, Monique (author)
Griffiths-Jones, Sam (author)
Ureta-Vidal, Abel (author)
Hoffman, Michael M (author)
Severin, Jessica (author)
Searle, Stephen M J (author)
Law, Andy S (author)
Speed, David (author)
Waddington, Dave (author)
Cheng, Ze (author)
Tuzun, Eray (author)
Eichler, Evan (author)
Bao, Zhirong (author)
Flicek, Paul (author)
Shteynberg, David D (author)
Brent, Michael R (author)
Bye, Jacqueline M (author)
Huckle, Elizabeth J (author)
Chatterji, Sourav (author)
Dewey, Colin (author)
Pachter, Lior (author)
Kouranov, Andrei (author)
Mourelatos, Zissimos (author)
Hatzigeorgiou, Artemis G (author)
Paterson, Andrew H (author)
Ivarie, Robert (author)
Brandström, Mikael (author)
Uppsala universitet,Evolutionsbiologi,Molecular Evolution
Axelsson, Erik (author)
Molecular Evolution
Backström, Niclas (author)
Uppsala universitet,Evolutionsbiologi,Molecular Evolution
Berlin, Sofia (author)
Uppsala universitet,Evolutionsbiologi,Molecular Evolution
Webster, Matthew T (author)
Uppsala universitet,Evolutionsbiologi,Molecular Evolution
Pourquie, Olivier (author)
Reymond, Alexandre (author)
Ucla, Catherine (author)
Antonarakis, Stylianos E (author)
Long, Manyuan (author)
Emerson, J J (author)
Betrán, Esther (author)
Dupanloup, Isabelle (author)
Kaessmann, Henrik (author)
Hinrichs, Angie S (author)
Bejerano, Gill (author)
Furey, Terrence S (author)
Harte, Rachel A (author)
Raney, Brian (author)
Siepel, Adam (author)
Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
Kent, W James (author)
Haussler, David (author)
Eyras, Eduardo (author)
Castelo, Robert (author)
Abril, Josep F (author)
Castellano, Sergi (author)
Camara, Francisco (author)
Parra, Genis (author)
Guigo, Roderic (author)
Bourque, Guillaume (author)
Tesler, Glenn (author)
Pevzner, Pavel A (author)
Smit, Arian (author)
Fulton, Lucinda A (author)
Mardis, Elaine R (author)
Wilson, Richard K (author)
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 (creator_code:org_t)
2004
2004
English.
In: Nature. - 0028-0836 .- 1476-4687. ; 432:7018, s. 695-716
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • We present here a draft genome sequence of the red jungle fowl, Gallus gallus. Because the chicken is a modern descendant of the dinosaurs and the first non-mammalian amniote to have its genome sequenced, the draft sequence of its genome--composed of approximately one billion base pairs of sequence and an estimated 20,000-23,000 genes--provides a new perspective on vertebrate genome evolution, while also improving the annotation of mammalian genomes. For example, the evolutionary distance between chicken and human provides high specificity in detecting functional elements, both non-coding and coding. Notably, many conserved non-coding sequences are far from genes and cannot be assigned to defined functional classes. In coding regions the evolutionary dynamics of protein domains and orthologous groups illustrate processes that distinguish the lineages leading to birds and mammals. The distinctive properties of avian microchromosomes, together with the inferred patterns of conserved synteny, provide additional insights into vertebrate chromosome architecture.

Subject headings

NATURVETENSKAP  -- Biologi -- Genetik (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Genetics (hsv//eng)

Keyword

Animals
Avian Proteins/genetics
Chickens/*genetics
Comparative Study
Conserved Sequence/genetics
DNA Transposable Elements/genetics
Evolution; Molecular
Gene Duplication
Genes/genetics
Genome
Genomics
Humans
Long Interspersed Nucleotide Elements/genetics
Multigene Family/genetics
Mutagenesis/genetics
Physical Chromosome Mapping
Pseudogenes/genetics
RNA; Untranslated/genetics
Research Support; Non-U.S. Gov't
Research Support; U.S. Gov't; Non-P.H.S.
Research Support; U.S. Gov't; P.H.S.
Retroviridae/genetics
Sequence Analysis; DNA
Short Interspersed Nucleotide Elements/genetics
Synteny
Vertebrates/genetics
Genetics
Genetik

Publication and Content Type

ref (subject category)
art (subject category)

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By the author/editor
Hillier, Ladeana ...
Miller, Webb
Birney, Ewan
Warren, Wesley
Hardison, Ross C
Ponting, Chris P
show more...
Bork, Peer
Burt, David W
Groenen, Martien ...
Delany, Mary E
Dodgson, Jerry B
Chinwalla, Asif ...
Cliften, Paul F
Clifton, Sandra ...
Delehaunty, Kimb ...
Fronick, Catrina
Fulton, Robert S
Graves, Tina A
Kremitzki, Colin
Layman, Dan
Magrini, Vincent
McPherson, John ...
Miner, Tracie L
Minx, Patrick
Nash, William E
Nhan, Michael N
Nelson, Joanne O
Oddy, Lachlan G
Pohl, Craig S
Randall-Maher, J ...
Smith, Scott M
Wallis, John W
Yang, Shiaw-Pyng
Romanov, Michael ...
Rondelli, Cather ...
Paton, Bob
Smith, Jacquelin ...
Morrice, David
Daniels, Laura
Tempest, Helen G
Robertson, Linds ...
Masabanda, Julio ...
Griffin, Darren ...
Vignal, Alain
Fillon, Valerie
Jacobbson, Lina
Kerje, Susanne
Andersson, Leif
Crooijmans, Rich ...
Aerts, Jan
van der Poel, Ja ...
Ellegren, Hans
Caldwell, Randol ...
Hubbard, Simon J
Grafham, Darren ...
Kierzek, Andrzej ...
McLaren, Stuart ...
Overton, Ian M
Arakawa, Hiroshi
Beattie, Kevin J
Bezzubov, Yuri
Boardman, Paul E
Bonfield, James ...
Croning, Michael ...
Davies, Robert M
Francis, Matthew ...
Humphray, Sean J
Scott, Carol E
Taylor, Ruth G
Tickle, Cheryll
Brown, William R ...
Rogers, Jane
Buerstedde, Jean ...
Wilson, Stuart A
Stubbs, Lisa
Ovcharenko, Ivan
Gordon, Laurie
Lucas, Susan
Miller, Marcia M
Inoko, Hidetoshi
Shiina, Takashi
Kaufman, Jim
Salomonsen, Jan
Skjoedt, Karsten
Wong, Gane Ka-Sh ...
Wang, Jun
Liu, Bin
Wang, Jian
Yu, Jun
Yang, Huanming
Nefedov, Mikhail
Koriabine, Maxim
Dejong, Pieter J
Goodstadt, Leo
Webber, Caleb
Dickens, Nichola ...
Letunic, Ivica
Suyama, Mikita
Torrents, David
von Mering, Chri ...
Zdobnov, Evgeny ...
Makova, Kateryna
Nekrutenko, Anto ...
Elnitski, Laura
Eswara, Pallavi
King, David C
Yang, Shan
Tyekucheva, Svit ...
Radakrishnan, An ...
Harris, Robert S
Chiaromonte, Fra ...
Taylor, James
He, Jianbin
Rijnkels, Moniqu ...
Griffiths-Jones, ...
Ureta-Vidal, Abe ...
Hoffman, Michael ...
Severin, Jessica
Searle, Stephen ...
Law, Andy S
Speed, David
Waddington, Dave
Cheng, Ze
Tuzun, Eray
Eichler, Evan
Bao, Zhirong
Flicek, Paul
Shteynberg, Davi ...
Brent, Michael R
Bye, Jacqueline ...
Huckle, Elizabet ...
Chatterji, Soura ...
Dewey, Colin
Pachter, Lior
Kouranov, Andrei
Mourelatos, Ziss ...
Hatzigeorgiou, A ...
Paterson, Andrew ...
Ivarie, Robert
Brandström, Mika ...
Axelsson, Erik
Backström, Nicla ...
Berlin, Sofia
Webster, Matthew ...
Pourquie, Olivie ...
Reymond, Alexand ...
Ucla, Catherine
Antonarakis, Sty ...
Long, Manyuan
Emerson, J J
Betrán, Esther
Dupanloup, Isabe ...
Kaessmann, Henri ...
Hinrichs, Angie ...
Bejerano, Gill
Furey, Terrence ...
Harte, Rachel A
Raney, Brian
Siepel, Adam
Kent, W James
Haussler, David
Eyras, Eduardo
Castelo, Robert
Abril, Josep F
Castellano, Serg ...
Camara, Francisc ...
Parra, Genis
Guigo, Roderic
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Tesler, Glenn
Pevzner, Pavel A
Smit, Arian
Fulton, Lucinda ...
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Wilson, Richard ...
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About the subject
NATURAL SCIENCES
NATURAL SCIENCES
and Biological Scien ...
and Genetics
Articles in the publication
Nature
By the university
Uppsala University

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