| 1. |
- Penttilä, S., et al.
(författare)
-
Late-onset spinal motor neuronopathy - A common form of dominant SMA
- 2014
-
Ingår i: Neuromuscular Disorders. - : Elsevier BV. - 0960-8966. ; 24:3, s. 259-268
-
Tidskriftsartikel (refereegranskat)abstract
- We previously described two Finnish families with a new autosomal dominant late-onset spinal motor neuronopathy that was mapped to chromosome 22q11.2-q13.2. In the current screening study of 43 lower motor neuron disease patients from Finland and Sweden, we identified 26 new late-onset spinal motor neuronopathy patients sharing the founder haplotype. In addition to the main symptoms and signs: painful cramps, fasciculations, areflexia and slowly evolving muscle weakness, new features such as mild bulbar findings, were identified. The disease is relatively benign in terms of life expectancy and rate of disability progression, and it is therefore noteworthy that three patients were initially misdiagnosed with ALS. Significant recombinants in this new patient cohort restricted the disease locus by 90% to 1.8. Mb. Late-onset spinal motor neuronopathy seems not to be very rare, at least not in Finland, with 38 patients identified in a preliminary ascertainment. © 2013 Elsevier B.V.
|
|
| 2. |
- Griep, Rosane Härter, et al.
(författare)
-
Work-family conflict, lack of time for personal care and leisure, and job strain in migraine : Results of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
- 2016
-
Ingår i: American Journal of Industrial Medicine. - : Wiley. - 0271-3586 .- 1097-0274. ; 59:11, s. 987-1000
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Work-family conflict and time scarcity may affect health. We investigated the association between these issues and migraine, taking into account job strain.METHODS: Baseline data from ELSA-Brasil (6,183 women; 5,664 men) included four indicators of work-family conflict: time- and strain-based interference of work with family (TB-WFC, SB-WFC), interference of family with work (FWC) and lack of time for personal care and leisure (LOT). Migraine was classified according to International Headache Society criteria.RESULTS: Among women, definite migraine was associated with SB-WFC (odds ratio [OR] = 1.28; 95% confidence interval [CI] 1.06-1.55), FWC (OR = 1.32; 1.00-1.75), and LOT (OR = 1.30; 1.08-1.58). Probable migraine was associated with SB-WFC (OR = 1.17; 1.00-1.36). High psychological job demands and low social support interacted with LOT in association with definite migraine. Among men, probable migraine was associated with LOT (OR = 1.34; 1.09-1.64), and there were interactions between job strain and WFC for probable migraine.CONCLUSIONS: Balancing the demands of professional and domestic spheres could be highly relevant in the management of migraines. Am. J. Ind. Med. 59:987-1000, 2016. © 2016 Wiley Periodicals, Inc.
|
|
| 3. |
- Hagqvist, Emma, 1980-, et al.
(författare)
-
Falling outside the system : Occupational safety and health inspectors’ experiences of micro-enterprises in Sweden
- 2020
-
Ingår i: Safety Science. - : Elsevier B.V.. - 0925-7535 .- 1879-1042. ; 125
-
Tidskriftsartikel (refereegranskat)abstract
- In this study, 11 Swedish occupational safety and health (OSH) inspectors were interviewed about their views of and experiences interacting with micro-enterprises (1-9 employees). The qualitative content analysis found one theme, “Falling outside the system”, and three subthemes, “The inspector—shaped by specific standards”, “The bureaucrat and the micro-entrepreneur—two separate worlds”, and “System faults and system changes”. According to the inspectors, the Swedish OSH regulatory system, with inspectors on the front line, neglects the specific needs, circumstances and characteristics of micro-enterprises. Therefore, we suggest revising the OSH regulatory system and following inspection methods and enforcement styles to better address the needs of micro-enterprises.
|
|
| 4. |
- Toivanen, Susanna, et al.
(författare)
-
Sjukhusinläggningar till följd av akuta hjärt-kärlsjukdomar: finns det skillnader mellan egenföretagare och anställda inom samma bransch?
- 2016
-
Ingår i: Book of abstracts - FALF 2016. - Östersund : Mittuniversitetet. ; , s. 42-43
-
Konferensbidrag (refereegranskat)abstract
- Bakgrund: Både bättre och sämre hälsa har tidigare rapporterats hos egenföretagare jämfört med anställda. Egenföretagare rapporterar oftast bättre livs- och arbetstillfredsställelse trots att de arbetar mer, tar kortare semester, är mer sällan sjukskrivna och oftare sjuknärvarande än anställda. Företagsform och bransch påverkar egenföretagares dödsrisk, även i jämförelse med anställda. Vad gäller sjukhusinläggningar till följd av akuta hjärt- kärlsjukdomar är kunskapen om skillnader mellan egenföretagare och anställda begränsad. Syftet var att undersöka sjukhusinläggningar till följd av akut hjärtinfarkt och stroke, var för sig, och analysera skillnader mellan egenföretagare och anställda inom samma branscher. Data och metod: Data från Statistiska centralbyråns befolkningsregister (2003) länkades till Socialstyrelsens patientregister och dödsorsaksregister (2004-2008). Drygt 4,7 miljoner individer (7 % egenföretagare) ingick i studien. Individer klassificerades utifrån yrkesställning som anställda, egenföretagare eller egenföretagare med aktiebolag. Utifrån Standard för svensk näringsgrensindelning (SNI 2002) klassificerades åtta branscher.Diagnos för sjukhusinläggning klassificerades som akut hjärtinfarkt (I21) och stroke (I61 intracerebral blödning; I63 cerebral infarkt; I64 ospecificerad akut cerebrovaskulär sjukdom) utifrån internationell klassificering av diagnoser (ICD-10). Sjukhusinläggningstal (incidens rate ratio, IRR med 95 % konfidensintervall, KI) estimerades med multipel Negative Binomial regressionsanalys. Två- och trevägsinteraktioner testades mellan yrkesställning, bransch och kön. Resultat: Risken för sjukhusinläggning till följd av akut hjärtinfarkt (IRR 0,92; KI 0,85-0,99) var signifikant lägre bland egenföretagare med aktiebolag jämfört med anställda, och högre i de flesta branscher (IRR 1,15 – 1,25) jämfört med jordbruk, skogsbruk och fiske (JSF). Förhöjd risk för sjukhusinläggning till följd av stroke fanns i samtliga branscher (IRR 1,19 – 1,48) jämfört med JSF, däremot fanns inga skillnader utifrån yrkesställning. Tvåvägsinteraktionen mellan yrkesställning och bransch var signifikant för hjärtinfarkt (p=0,0019). Jämfört med anställda hade egenföretagare förhöjd risk för sjukhusinläggning inom handel, restaurang och transport (IRR 1,22; KI 1,09-1,38) samt lägre risk inom JSF (IRR 0,81; KI 0,68-0,97) och i icke specificerade branscher (IRR 0,79; KI 0,67- 0,93).
|
|
| 5. |
- Griep Härter, Rosane, et al.
(författare)
-
Years worked at night and body mass index among registered nurses from eighteen public hospitals in Rio de Janeiro, Brazil
- 2014
-
Ingår i: BMC Health Services Research. - : Springer Science and Business Media LLC. - 1472-6963. ; 14
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Employees working night shifts are at a greater risk of being overweight or obese. Few studies on obesity and weight gain analyze the years of exposure to night work. The aim of this study was to determine the relationship between the years of exposure to night work and body mass index (BMI) among registered nurses.METHODS: A cross-sectional analysis was performed in 18 largest public hospitals in Rio de Janeiro, Brazil. A total of 2,372 registered nurses (2,100 women) completed a comprehensive questionnaire concerning sociodemographic, professional, lifestyle, and health behavioral data. Current and past exposures to night shifts as well as BMI values were measured as continuous variables. A gamma regression model was used with an identity link function to establish the association.RESULTS: The association between years of exposure to night work and BMI was statistically significant for both women and men after adjusting for all covariates [β = 0.036; CI95% = 0.009-0.063) and β = 0.071 (CI95% = 0.012-0.129), respectively]. The effect of night work was greater among men than women. For example, for those women who have worked at night for 20 years the estimated average BMI was 25.6 kg/m2 [range, 25.0-26.2]. In relation to men, after 20 years of exposure to night work the estimated average BMI was 26.9 kg/m2 [range, 25.6-28.1].CONCLUSIONS: These findings suggest that night shift exposure is related to BMI increases. Obesity prevention strategies should incorporate improvements in work environments, such as the provision of proper meals to night workers, in addition to educational programs on the health effects of night work.
|
|
| 6. |
- Juvanhol, Leidjaira Lopes, et al.
(författare)
-
Is work-family conflict a pathway between job strain components and binge eating? A cross-sectional analysis from the ELSA-Brasil study
- 2022
-
Ingår i: Journal of Eating Disorders. - : Springer Science and Business Media LLC. - 2050-2974. ; 10:1
-
Tidskriftsartikel (refereegranskat)abstract
- BackgroundJob strain has been reported as a trigger for binge eating, yet the underlying mechanisms have been unclear. The aim of this study was to evaluate whether work-family conflict is a pathway in the association between job strain and binge eating, considering the possible effect-modifying influence of body mass index (BMI).MethodsThis cross-sectional analysis included 12,084 active civil servants from the multicenter Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Job strain was assessed using the Demand-Control-Support Questionnaire. Work-family conflict was considered as a latent variable comprising three items. Binge eating was defined as eating a large amount of food in less than 2 h at least twice a week in the last six months with a sense of lack of control over what and how much was eaten. Structural equation modelling was used to test the role of work-family conflict in the association between job strain and binge eating, stratifying for BMI.ResultsFor individuals of normal weight, positive associations were found between skill discretion and binge eating (standardized coefficient [SC] = 0.209, 95%CI = 0.022–0.396), and between psychological job demands and work-family conflict (SC = 0.571, 95%CI = 0.520–0.622), but no statistically significant indirect effect was found. In overweight individuals, psychological job demands, skill discretion, and work-family conflict were positively associated with binge eating (SC = 0.099, 95%CI = 0.005–0.193; SC = 0.175, 95%CI = 0.062–0.288; and SC = 0.141, 95%CI = 0.077–0.206, respectively). Also, work-family conflict was observed to be a pathway on the associations of psychological job demands and decision authority with binge eating (SC = 0.084, 95%CI = 0.045–0.122; and SC = − 0.008, 95%CI = − 0.015– − 0.001, respectively).ConclusionsWork-family conflict partly explains effects of high levels of psychological job demands and low levels of decision authority on binge eating among overweight individuals. Moreover, skill discretion is positively associated with binge eating, regardless of BMI category.
|
|
