Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Visser M C) "

Sökning: WFRF:(Visser M C)

Sortera/gruppera träfflistan
  • 2017
  • swepub:Mat__t
  • Lissner, Lauren, 1956, et al. (författare)
  • Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC)
  • 2021
  • Ingår i: eLife. - : eLife Sciences Publications Ltd. - 2050-084X. ; 10
  • Tidskriftsartikel (refereegranskat)abstract
    • From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions.
  • Bixby, H., et al. (författare)
  • Rising rural body-mass index is the main driver of the global obesity epidemic in adults
  • 2019
  • Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 569:7755, s. 260-4
  • Tidskriftsartikel (refereegranskat)abstract
    • Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities(.)(1,2) This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity(3-6). Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017-and more than 80% in some low- and middle-income regions-was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing-and in some countries reversal-of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.
  • Adrian-Martinez, S., et al. (författare)
  • A first search for coincident gravitational waves and high energy neutrinos using LIGO, Virgo and ANTARES data from 2007
  • 2013
  • Ingår i: Journal of Cosmology and Astroparticle Physics. - : IOP Publishing. - 1475-7516. ; :6
  • Tidskriftsartikel (refereegranskat)abstract
    • We present the results of the first search for gravitational wave bursts associated with high energy neutrinos. Together, these messengers could reveal new, hidden sources that are not observed by conventional photon astronomy, particularly at high energy. Our search uses neutrinos detected by the underwater neutrino telescope ANTARES in its 5 line configuration during the period January - September 2007, which coincided with the fifth and first science runs of LIGO and Virgo, respectively. The LIGO-Virgo data were analysed for candidate gravitational-wave signals coincident in time and direction with the neutrino events. No significant coincident events were observed. We place limits on the density of joint high energy neutrino - gravitational wave emission events in the local universe, and compare them with densities of merger and core-collapse events.
  • Mishra, A., et al. (författare)
  • Stroke genetics informs drug discovery and risk prediction across ancestries
  • 2022
  • Ingår i: Nature. - : Nature Publishing Group. - 0028-0836 .- 1476-4687. ; 611
  • Tidskriftsartikel (refereegranskat)abstract
    • Previous genome-wide association studies (GWASs) of stroke - the second leading cause of death worldwide - were conducted predominantly in populations of European ancestry(1,2). Here, in cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-European) and 1,503,898 control individuals, we identify association signals for stroke and its subtypes at 89 (61 new) independent loci: 60 in primary inverse-variance-weighted analyses and 29 in secondary meta-regression and multitrait analyses. On the basis of internal cross-ancestry validation and an independent follow-up in 89,084 additional cases of stroke (30% non-European) and 1,013,843 control individuals, 87% of the primary stroke risk loci and 60% of the secondary stroke risk loci were replicated (P < 0.05). Effect sizes were highly correlated across ancestries. Cross-ancestry fine-mapping, in silico mutagenesis analysis(3), and transcriptome-wide and proteome-wide association analyses revealed putative causal genes (such as SH3PXD2A and FURIN) and variants (such as at GRK5 and NOS3). Using a three-pronged approach(4), we provide genetic evidence for putative drug effects, highlighting F11, KLKB1, PROC, GP1BA, LAMC2 and VCAM1 as possible targets, with drugs already under investigation for stroke for F11 and PROC. A polygenic score integrating cross-ancestry and ancestry-specific stroke GWASs with vascular-risk factor GWASs (integrative polygenic scores) strongly predicted ischaemic stroke in populations of European, East Asian and African ancestry(5). Stroke genetic risk scores were predictive of ischaemic stroke independent of clinical risk factors in 52,600 clinical-trial participants with cardiometabolic disease. Our results provide insights to inform biology, reveal potential drug targets and derive genetic risk prediction tools across ancestries.
Skapa referenser, mejla, bekava och länka
Typ av publikation
tidskriftsartikel (223)
konferensbidrag (10)
forskningsöversikt (7)
Typ av innehåll
refereegranskat (227)
övrigt vetenskapligt (13)
Scheltens, P (37)
Wallin, Anders, 1950 (27)
Tsolaki, M (27)
Zetterberg, Henrik, ... (26)
Scheltens, Philip (26)
Visser, P. J. (26)
visa fler...
Blennow, Kaj, 1958 (25)
Visser, PJ (23)
van Dishoeck, E. F. (21)
Liseau, René, 1949 (20)
Visser, R. (20)
Barkhof, F (19)
Caselli, P. (19)
Benz, A. O. (19)
Johnstone, D. (18)
Wyrowski, F. (18)
Herpin, F. (18)
Bruderer, S. (18)
Nisini, B. (18)
Tafalla, M. (18)
Larsson, Bengt (17)
Bachiller, R. (17)
Visser, M. (17)
Olberg, Michael, 195 ... (17)
Risacher, C. (17)
di Giorgio, A. M. (17)
Fich, M. (17)
Goicoechea, J. R. (17)
Saraceno, P. (17)
Shipman, R. (17)
van Kempen, T. A. (17)
Yıldız, U. A. (17)
Cernicharo, J. (16)
Dominik, C. (16)
Hogerheijde, M. R. (16)
Bontemps, S. (16)
Fuente, A. (16)
Braine, J. (16)
Baudry, A. (16)
Helmich, F. (16)
Benedettini, M. (16)
Bjerkeli, Per, 1977 (16)
Codella, C. (16)
Daniel, F. (16)
Encrenaz, P. (16)
Giannini, T. (16)
Lis, D. (16)
McCoey, C. (16)
Parise, B. (16)
Plume, R. (16)
visa färre...
Karolinska Institutet (107)
Göteborgs universitet (71)
Lunds universitet (41)
Uppsala universitet (30)
Umeå universitet (26)
Chalmers tekniska högskola (25)
visa fler...
Stockholms universitet (22)
Örebro universitet (19)
Linköpings universitet (4)
Sveriges Lantbruksuniversitet (4)
Kungliga Tekniska Högskolan (3)
Linnéuniversitetet (3)
Naturhistoriska riksmuseet (2)
visa färre...
Engelska (240)
Tyska (1)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (118)
Naturvetenskap (53)
Samhällsvetenskap (4)
Teknik (1)


Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy