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Träfflista för sökning "WFRF:(Wahlgren M) ;conttype:(refereed);pers:(Jiang N)"

Search: WFRF:(Wahlgren M) > Peer-reviewed > Jiang N

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1.	Zhang, Y, et al. (author) A comparative study on the heparin-binding proteomes of Toxoplasma gondii and Plasmodium falciparum 2014 In: Proteomics. - : Wiley. - 1615-9861 .- 1615-9853. ; 14:15, s. 1737-1745 Journal article (peer-reviewed)
2.	Chang, ZG, et al. (author) The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate 2016 In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 7, s. 11537- Journal article (peer-reviewed)abstract Neutrophil extracellular traps (NETs), composed primarily of DNA and proteases, are released from activated neutrophils and contribute to the innate immune response by capturing pathogens. Plasmodium falciparum, the causative agent of severe malaria, thrives in its host by counteracting immune elimination. Here, we report the discovery of a novel virulence factor of P. falciparum, a TatD-like DNase (PfTatD) that is expressed primarily in the asexual blood stage and is likely utilized by the parasite to counteract NETs. PfTatD exhibits typical deoxyribonuclease activity, and its expression is higher in virulent parasites than in avirulent parasites. A P. berghei TatD-knockout parasite displays reduced pathogenicity in mice. Mice immunized with recombinant TatD exhibit increased immunity against lethal challenge. Our results suggest that the TatD-like DNase is an essential factor for the survival of malarial parasites in the host and is a potential malaria vaccine candidate.
3.	Du, C, et al. (author) Immunogenicity of the Plasmodium falciparum Pf332-DBL domain in combination with different adjuvants 2010 In: Vaccine. - : Elsevier BV. - 1873-2518 .- 0264-410X. ; 28:31, s. 4977-4983 Journal article (peer-reviewed)
4.	Jiang, N, et al. (author) Characterization of the Catalytic Subunits of the RNA Exosome-like Complex in Plasmodium falciparum 2018 In: The Journal of eukaryotic microbiology. - : Wiley. - 1550-7408 .- 1066-5234. ; 65:6, s. 843-853 Journal article (peer-reviewed)
5.	Jiang, N, et al. (author) Co-infections with Plasmodium knowlesi and other malaria parasites, Myanmar 2010 In: Emerging infectious diseases. - : Centers for Disease Control and Prevention (CDC). - 1080-6059 .- 1080-6040. ; 16:9, s. 1476-1478 Journal article (peer-reviewed)
6.	Nilsson, S, et al. (author) Characterization of the Duffy-Binding-Like Domain of Plasmodium falciparum Blood-Stage Antigen 332 2011 In: Malaria research and treatment. - : Hindawi Limited. - 2044-4362. ; 2011, s. 671439- Journal article (peer-reviewed)abstract Studies on Pf332, a major Plasmodium falciparum blood-stage antigen, have largely been hampered by the cross-reactive nature of antibodies generated against the molecule due to its high content of repeats, which are present in other malaria antigens. We previously reported the identification of a conserved domain in Pf332 with a high degree of similarity to the Duffy-binding-like (DBL) domains of the erythrocyte-binding-like (EBL) family. We here describe that antibodies towards Pf332-DBL are induced after repeated exposure to P. falciparum and that they are acquired early in life in areas of intense malaria transmission. Furthermore, a homology model of Pf332-DBL was found to be similar to the structure of the EBL-DBLs. Despite their similarities, antibodies towards Pf332-DBL did not display any cross-reactivity with EBL-proteins as demonstrated by immunofluorescence microscopy, Western blotting, and peptide microarray. Thus the DBL domain is an attractive region to use in further studies on the giant Pf332 molecule.
7.	Wang, W, et al. (author) A Thioredoxin Homologous Protein of Plasmodium falciparum Participates in Erythrocyte Invasion 2018 In: Infection and immunity. - 1098-5522. ; 86:8 Journal article (peer-reviewed)
8.	Zhang, Y, et al. (author) Proteomic analysis of Plasmodium falciparum schizonts reveals heparin-binding merozoite proteins 2013 In: Journal of proteome research. - : American Chemical Society (ACS). - 1535-3907 .- 1535-3893. ; 12:5, s. 2185-2193 Journal article (peer-reviewed)
9.	Zhang, YN, et al. (author) The var3 genes of Plasmodium falciparum 3D7 strain are differentially expressed in infected erythrocytes 2014 In: Parasite (Paris, France). - : EDP Sciences. - 1776-1042. ; 21, s. 19- Journal article (peer-reviewed)

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Result 1-9 of 9

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Type of publication: journal article (9)

Type of content: peer-reviewed (9)Undo refine

Author/Editor: Wahlgren, M (9); Jiang, N (9)Undo refine; Chen, QJ (8); Lu, HJ (7); Yin, JG (5); Chang, ZG (3); show more...; Zhang, Y. (2); Nilsson, S. (2); Yu, SC (2); Zhang, YN (2); Sun, X. (1); Zhao, X. (1); Song, M. (1); Wang, Y. (1); Wang, W. (1); Zhang, K. (1); Chen, Q. (1); Berzins, K (1); Moll, K (1); Albrecht, L (1); Angeletti, D (1); Zhang, YY (1); Cheng, XJ (1); Zhang, ZX (1); Zhang, DC (1); Zhou, JH (1); Feng, Y. (1); Yang, N (1); Huang, P (1); Cao, YM (1); Wei, XY (1); Wang, DW (1); Tu, ZW (1); Du, C. (1); Cai, PF (1); Sang, XY (1); Chang, QC (1); Sun, XD (1); Kursula, I (1); Wang, HN (1); Hou, N. (1); Jia, BY (1); Piao, XY (1); Wang, HA (1); show less...

University: Karolinska Institutet (9)

Language: English (9)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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