↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Wallin Anders 1950) ;pers:(Minthon Lennart 1951)"

Sökning: WFRF:(Wallin Anders 1950) > Minthon Lennart 1951

Resultat 1-4 av 4

Sortera/gruppera träfflistan

Sortering: Träffar per sida:

Numrering	Referens	Omslagsbild	Hitta
1.	Bjerke, Maria, 1977, et al. (författare) Confounding factors influencing amyloid Beta concentration in cerebrospinal fluid. 2010 Ingår i: International journal of Alzheimer's disease. - : Hindawi Limited. - 2090-0252. ; 2010 Tidskriftsartikel (refereegranskat)abstract Background. Patients afflicted with Alzheimer's disease (AD) exhibit a decrease in the cerebrospinal fluid (CSF) concentration of the 42 amino acid form of beta-amyloid (Abeta(42)). However, a high discrepancy between different centers in measured Abeta(42) levels reduces the utility of this biomarker as a diagnostic tool and in monitoring the effect of disease modifying drugs. Preanalytical and analytical confounding factors were examined with respect to their effect on the measured Abeta(42) level. Methods. Aliquots of CSF samples were either treated differently prior to Abeta(42) measurement or analyzed using different commercially available xMAP or ELISA assays. Results. Confounding factors affecting CSF Abeta(42) levels were storage in different types of test tubes, dilution with detergent-containing buffer, plasma contamination, heat treatment, and the origin of the immunoassays used for quantification. Conclusion. In order to conduct multicenter studies, a standardized protocol to minimize preanalytical and analytical confounding factors is warranted.
2.	Blennow, Kaj, 1958, et al. (författare) Evolution of Abeta42 and Abeta40 Levels and Abeta42/Abeta40 Ratio in Plasma during Progression of Alzheimer's Disease: A Multicenter Assessment. 2009 Ingår i: The journal of nutrition, health & aging. - 1279-7707. ; 13:3, s. 205-8 Tidskriftsartikel (refereegranskat)abstract Objective: To better understand the seemingly contradictory plasma beta-amyloid (Abeta) results in Alzheimer's disease (AD) patients by using a newly developed plasma Abeta assay, the INNO-BIA plasma Abeta forms, in a multicenter study. Methods: A combined retrospective analysis of plasma Abeta isoforms on mild cognitive impairment (MCI) from three large cross-sectional studies involving 643 samples from the participating German and Swedish centers. Results: Detection modules based on two different amino (N)-terminal specific Abeta monoclonal antibodies demonstrated that Abeta in plasma could be reliable quantified using a sandwich immunoassay technology with high precision, even for low Abeta42 plasma concentrations. Abeta40 and Abeta42 concentrations varied consistently with the ApoE genotype, while the Abeta42/Abeta40 ratio did not. Irrespective of the decrease of the Abeta42/Abeta40 ratio with age and MMSE, this parameter was strongly associated with AD, as defined in this study by elevated hyperphosphorylated (P-tau181P) levels in cerebrospinal fluid (CSF). Conclusion: A highly robust assay for repeatedly measuring Abeta forms in plasma such as INNO-BIA plasma Abeta forms might be a useful tool in a future risk assessment of AD.
3.	Blennow, Kaj, 1958, et al. (författare) [There is a strong evidence that professional boxing results in chronic brain damage. The more head punches during a boxer's career, the bigger is the risk] : Starka belägg för att proffsboxning leder till kroniska hjärnskador. Ju fler slag mot huvudet under en boxares karriär, desto större är risken 2005 Ingår i: Läkartidningen. - 0023-7205. ; 102:36 Forskningsöversikt (refereegranskat)abstract The clinical symptomatology and pathogenic mechanisms of chronic traumatic brain injury associated with boxing (CTBI-B) is reviewed. This syndrome is also known as punch drunk syndrome or dementia pugilistica. Since even milder forms of CTBI-B are rare among amateur boxers, we make a distinction between amateur and professional boxing throughout the review. Focus is also set on the interesting similarities in neurochemical changes and pathogenic mechanisms between CTBI-B, acute traumatic brain injury (e.g. road traffic accidents) and Alzheimer's disease.
4.	Winblad, B, et al. (författare) Forskarflykten slår hårt mot läkemedelsindustrin 2008 Ingår i: Dagens Industri 22 sept 2008. Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)

Skapa referenser, mejla, bekava och länka

Länka till träfflistan

Resultat 1-4 av 4

Avgränsa träffmängd

Typ av publikation: tidskriftsartikel (3); forskningsöversikt (1)

Typ av innehåll: refereegranskat (3); övrigt vetenskapligt/konstnärligt (1)

Författare/redaktör: Blennow, Kaj, 1958 (4); Wallin, Anders, 1950 (4); Minthon, Lennart... (4)Ta bort avgränsningen; Zetterberg, Henrik, ... (3); Winblad, B (1); Nordberg, A (1); visa fler...; Wahlund, LO (1); Johansson, G. (1); Olson, L (1); Skoog, Ingmar, 1954 (1); Portelius, Erik, 197 ... (1); Hansson, O. (1); Anckarsäter, Henrik, ... (1); Björkhem, I (1); Wiltfang, J (1); Andreasson, Ulf, 196 ... (1); Marcusson, J (1); Graff, C (1); Eriksson, E (1); Anckarsäter, Rolf, 1 ... (1); Johansson, Boo (1); Andreasen, Niels (1); Vanderstichele, H (1); Vanmechelen, E (1); Wimo, A (1); Långström, B. (1); Kornhuber, J (1); Edberg, AK (1); Eriksdotter-Jönhagen ... (1); Borell, L (1); Bjerke, Maria, 1977 (1); De Meyer, G. (1); Lewczuk, P. (1); Rasulzada, Abdullah (1); Popa, Cornel, 1980 (1); SANDMAN, PO (1); Bucht, G (1); Bäckman, L (1); visa färre...

Lärosäte: Göteborgs universitet (4); Karolinska Institutet (1)

Språk: Svenska (2); Engelska (2)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (3)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - Nationella bibliotekssystem
LIBRIS.kb.se

pil uppåt

Stäng

Kopiera och spara länken för att återkomma till aktuell vy