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Mouse chromosome 19...
Mouse chromosome 19 and distal rat chromosome 1: a chromosome segment conserved in evolution.
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Yamasaki, Y (author)
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- Helou, Khalil, 1966 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för särskilda specialiteter, Avdelningen för onkologi,Institute of Selected Clinical Sciences, Department of Oncology
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Watanabe, T K (author)
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- Sjöling, Åsa, 1968 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för cell- och molekylärbiologi, genetik,Department of Cell and Molecular Biology, Genetics
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Suzuki, M (author)
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Okuno, S (author)
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Ono, T (author)
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Takagi, T (author)
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Nakamura, Y (author)
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- Ståhl, Fredrik, 1956 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för cell- och molekylärbiologi, genetik,Department of Cell and Molecular Biology, Genetics
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Tanigami, A (author)
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(creator_code:org_t)
- Wiley-Blackwell Publishing, Inc. 2001
- 2001
- English.
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In: Hereditas. - : Wiley-Blackwell Publishing, Inc.. - 0018-0661 .- 1601-5223. ; 134:1, s. 23-34
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Through a combination of radiation hybrid mapping and studies by FISH and zoo-FISH we have made a comparative investigation of the distal portion of rat chromosome 1 (RNO1) and the entire mouse chromosome 19 (MMU19). It was found that homologous segments of RNO1 and MMU19 are similar in banding morphology and in length as determined by several different methods, and that the gene order of the 46 genes studied appears to be conserved across the homologous segments in the two species. High-resolution zoo-FISH techniques showed that MMU19 probes highlight only a continuous segment on RNO1 (1q43-qter), with no detectable signals on other rat chromosomes. We conclude that these data suggest the evolutionary conservation of a chromosomal segment from a common rodent ancestor. This segment now constitutes the entire MMU19 and a large segment distally on RNO1q in the mouse and rat, respectively.
Subject headings
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
Keyword
- Animals
- Cells
- Cultured
- Chromosome Mapping
- Chromosomes
- genetics
- ultrastructure
- Evolution
- Molecular
- In Situ Hybridization
- Fluorescence
- Mice
- genetics
- Phylogeny
- Quantitative Trait
- Heritable
- Radiation Hybrid Mapping
- Rats
- genetics
- Rodentia
- classification
- genetics
- Species Specificity
Publication and Content Type
- ref (subject category)
- art (subject category)
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Hereditas
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- By the author/editor
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Yamasaki, Y
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Helou, Khalil, 1 ...
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Watanabe, T K
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Sjöling, Åsa, 19 ...
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Suzuki, M
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Okuno, S
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show more...
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Ono, T
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Takagi, T
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Nakamura, Y
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Ståhl, Fredrik, ...
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Tanigami, A
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show less...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
- Articles in the publication
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Hereditas
- By the university
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University of Gothenburg
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University of Borås