Tyck till om SwePub Sök
här!
Search: WFRF:(Wennberg Bertil)
> (2015-2019)
> Norberg Margareta >
Visualization of as...
Visualization of asymptomatic atherosclerotic disease for optimum cardiovascular prevention (VIPVIZA) : a pragmatic, open-label, randomised controlled trial
-
- Näslund, Ulf (author)
- Umeå universitet,Avdelningen för medicin,Arcum,Umeå Univ, Heart Ctr, Umeå, Sweden; Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden
-
- Ng, Nawi (author)
- Umeå universitet,Epidemiologi och global hälsa,Arcum,Umeå Univ, Unit Epidemiol & Global Hlth, Umeå, Sweden
-
- Lundgren, Anna, 1973- (author)
- Umeå universitet,Epidemiologi och global hälsa,Umeå Univ, Unit Epidemiol & Global Hlth, Umeå, Sweden
-
show more...
-
- Fhärm, Eva (author)
- Umeå universitet,Allmänmedicin,Umeå Univ, Unit Family Med, Umeå, Sweden
-
- Grönlund, Christer (author)
- Umeå universitet,Radiofysik,Umeå Univ, Dept Publ Hlth & Clin Med, Dept Radiat Sci, Umeå, Sweden
-
- Johansson, Helene, 1962- (author)
- Umeå universitet,Epidemiologi och global hälsa,Umeå Univ, Unit Epidemiol & Global Hlth, Umeå, Sweden
-
- Lindahl, Bernt (author)
- Umeå universitet,Yrkes- och miljömedicin,Umeå Univ, Unit Occupat & Environm Med, Umeå, Sweden
-
- Lindahl, Bertil, 1957- (author)
- Uppsala universitet,Institutionen för medicinska vetenskaper,Uppsala kliniska forskningscentrum (UCR)
-
- Lindvall, Kristina, 1981- (author)
- Umeå universitet,Epidemiologi och global hälsa,Umeå Univ, Unit Epidemiol & Global Hlth, Umeå, Sweden
-
- Nilsson, Stefan K., 1979- (author)
- Umeå universitet,Fysiologisk kemi,Umeå Univ, Unit Physiol Chem, Dept Med Biosci, Umeå, Sweden
-
- Nordin, Maria (author)
- Umeå universitet,Institutionen för psykologi,Umeå Univ, Dept Psychol, Umeå, Sweden
-
- Nordin, Steven, 1960- (author)
- Umeå universitet,Institutionen för psykologi,Umeå Univ, Dept Psychol, Umeå, Sweden
-
- Nyman, Emma (author)
- Umeå universitet,Avdelningen för medicin,Umeå Univ, Heart Ctr, Umeå, Sweden; Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden
-
- Rocklöv, Joacim, Professor, 1979- (author)
- Umeå universitet,Yrkes- och miljömedicin,Arcum,Umeå Univ, Unit Occupat & Environm Med, Umeå, Sweden
-
- Vanoli, Davide (author)
- Umeå universitet,Avdelningen för medicin,Umeå Univ, Heart Ctr, Umeå, Sweden; Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden
-
- Weinehall, Lars (author)
- Umeå universitet,Epidemiologi och global hälsa,Arcum,Umeå Univ, Unit Epidemiol & Global Hlth, Umeå, Sweden
-
- Wennberg, Patrik, 1972- (author)
- Umeå universitet,Allmänmedicin,Umeå Univ, Unit Family Med, Umeå, Sweden
-
- Wester, Per (author)
- Karolinska Institutet,Umeå universitet,Medicin,Umeå Univ, Unit Med, Umeå, Sweden
-
- Norberg, Margareta (author)
- Umeå universitet,Epidemiologi och global hälsa,Arcum,Umeå Univ, Unit Epidemiol & Global Hlth, Umeå, Sweden
-
show less...
-
(creator_code:org_t)
- Elsevier, 2019
- 2019
- English.
-
In: The Lancet. - : Elsevier. - 0140-6736 .- 1474-547X. ; 393:10167, s. 133-142
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- BACKGROUND: Primary prevention of cardiovascular disease often fails because of poor adherence among practitioners and individuals to prevention guidelines. We aimed to investigate whether ultrasound-based pictorial information about subclinical carotid atherosclerosis, targeting both primary care physicians and individuals, improves prevention.METHODS: Visualization of asymptomatic atherosclerotic disease for optimum cardiovascular prevention (VIPVIZA) is a pragmatic, open-label, randomised controlled trial that was integrated within the Västerbotten Intervention Programme, an ongoing population-based cardiovascular disease prevention programme in northern Sweden. Individuals aged 40, 50, or 60 years with one or more conventional risk factors were eligible to participate. Participants underwent clinical examination, blood sampling, and ultrasound assessment of carotid intima media wall thickness and plaque formation. Participants were randomly assigned 1:1 with a computer-generated randomisation list to an intervention group (pictorial representation of carotid ultrasound plus a nurse phone call to confirm understanding) or a control group (not informed). The primary outcomes, Framingham risk score (FRS) and European systematic coronary risk evaluation (SCORE), were assessed after 1 year among participants who were followed up. This study is registered with ClinicalTrials.gov, number NCT01849575.FINDINGS: 3532 individuals were enrolled between April 29, 2013, and June 7, 2016, of which 1783 were randomly assigned to the control group and 1749 were assigned to the intervention group. 3175 participants completed the 1-year follow-up. At the 1-year follow-up, FRS and SCORE differed significantly between groups (FRS 1·07 [95% CI 0·11 to 2·03, p=0·0017] and SCORE 0·16 [0·02 to 0·30, p=0·0010]). FRS decreased from baseline to the 1-year follow-up in the intervention group and increased in the control group (-0·58 [95% CI -0·86 to -0·30] vs 0·35 [0·08 to 0·63]). SCORE increased in both groups (0·13 [95% CI 0·09 to 0·18] vs 0·27 [0·23 to 0·30]).INTERPRETATION: This study provides evidence of the contributory role of pictorial presentation of silent atherosclerosis for prevention of cardiovascular disease. It supports further development of methods to reduce the major problem of low adherence to medication and lifestyle modification.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
-
The Lancet
(Search for host publication in LIBRIS)
To the university's database
- By the author/editor
-
Näslund, Ulf
-
Ng, Nawi
-
Lundgren, Anna, ...
-
Fhärm, Eva
-
Grönlund, Christ ...
-
Johansson, Helen ...
-
show more...
-
Lindahl, Bernt
-
Lindahl, Bertil, ...
-
Lindvall, Kristi ...
-
Nilsson, Stefan ...
-
Nordin, Maria
-
Nordin, Steven, ...
-
Nyman, Emma
-
Rocklöv, Joacim, ...
-
Vanoli, Davide
-
Weinehall, Lars
-
Wennberg, Patrik ...
-
Wester, Per
-
Norberg, Margare ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Health Sciences
-
and Public Health Gl ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cardiac and Card ...
- Articles in the publication
-
The Lancet
- By the university
-
Umeå University
-
Uppsala University
-
Karolinska Institutet