| 1. |
- Pilthammar, Jan, et al.
(författare)
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New press deflection measuring methods for the creation of substitutive models for efficient die cambering
- 2021
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Ingår i: IOP Conference Series. - : IOP Publishing. - 1757-8981 .- 1757-899X. ; 1157
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Tidskriftsartikel (refereegranskat)abstract
- Cost and time for die tryout are significant within the car industry, and elastic deflections of dies and presses are most commonly not considered during the virtual die design and forming simulation phase. Because of this, active surfaces of stamping dies are only cambered based on previous experiences of tool types and presses. However, almost all stamping dies and presses are unique, and available experiences are not valid for new materials. Partners within the Eureka SMART Advanced Manufacturing research project CAMBER have developed advanced deflection measuring devices to quantify the elastic deformations of presses. Using these measurements, cambering methodologies can be utilized in sheet metal forming simulations. Important breakthroughs in recent years enabling the cambering methodology consists of efficient simulation strategies for full scale simulations with elastic dies and optimization techniques for creating substitutive press structures based on measurements. Furthermore, modern press deflection measurement methods are beneficial in applications such as Industry 4.0, predictive maintenance, product quality control, etc. through a more advanced understanding and live monitoring of the press system.
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| 2. |
- Stading, Mats, 1962, et al.
(författare)
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A Device that Models Human Swallowing
- 2019
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Ingår i: Dysphagia. - : Springer Science and Business Media LLC. - 0179-051X .- 1432-0460. ; 34:5, s. 615-626
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Forskningsöversikt (refereegranskat)abstract
- The pharynx is critical for correct swallowing, facilitating the transport of both air and food transport in a highly coordinated manner, and aberrant co-ordination causes swallowing disorders (dysphagia). In this work, an in vitro model of swallowing was designed to investigate the role of rheology in swallowing and for use as a pre-clinical tool for simulation of different routes to dysphagia. The model is based on the geometry of the human pharynx. Manometry is used for pressure measurements and ultrasonic analysis is performed to analyze the flow profiles and determine shear rate in the bolus, the latter being vital information largely missing in literature. In the fully automated model, bolus injection, epiglottis/nasopharynx movement, and ultrasound transducer positioning can be controlled. Simulation of closing of the airways and nasal cavity is modulated by the software, as is a clamping valve that simulates the upper esophageal sphincter. The actions can be timed and valves opened to different degrees, resembling pathologic swallowing conditions. To validate measurements of the velocity profile and manometry, continuous and bolus flow was performed. The respective velocity profiles demonstrated the accuracy and validity of the flow characterization necessary for determining bolus flow. A maximum bolus shear rate of 80 s−1 was noted for syrup-consistency fluids. Similarly, the manometry data acquired compared very well with clinical studies.
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| 3. |
- Waqas, Muhammad, 1983, et al.
(författare)
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Assessment of the Food-Swallowing Process Using Bolus Visualisation and Manometry Simultaneously in a Device that Models Human Swallowing
- 2019
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Ingår i: Dysphagia. - : Springer Science and Business Media LLC. - 0179-051X .- 1432-0460. ; 34:6, s. 821-833
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Forskningsöversikt (refereegranskat)abstract
- The characteristics of the flows of boluses with different consistencies, i.e. different rheological properties, through the pharynx have not been fully elucidated. The results obtained using a novel in vitro device, the Gothenburg Throat, which allows simultaneous bolus flow visualisation and manometry assessments in the pharynx geometry, are presented, to explain the dependence of bolus flow on bolus consistency. Four different bolus consistencies of a commercial food thickener, 0.5, 1, 1.5 and 2 Pa s (at a shear rate of 50 s −1 )—corresponding to a range from low honey-thick to pudding-thick consistencies on the National Dysphagia Diet (NDD) scale—were examined in the in vitro pharynx. The bolus velocities recorded in the simulator pharynx were in the range of 0.046–0.48 m/s, which is within the range reported in clinical studies. The corresponding wall shear rates associated with these velocities ranged from 13 s −1 (pudding consistency) to 209 s −1 (honey-thick consistency). The results of the in vitro manometry tests using different consistencies and bolus volumes were rather similar to those obtained in clinical studies. The in vitro device used in this study appears to be a valuable tool for pre-clinical analyses of thickened fluids. Furthermore, the results show that it is desirable to consider a broad range of shear rates when assessing the suitability of a certain consistency for swallowing.
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| 4. |
- Waqas, Muhammad, 1983, et al.
(författare)
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Simultaneous X-ray Video-Fluoroscopy and Pulsed Ultrasound Velocimetry Analyses of the Pharyngeal Phase of Swallowing of Boluses with Different Rheological Properties
- 2020
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Ingår i: Dysphagia. - : Springer Science and Business Media LLC. - 0179-051X .- 1432-0460. ; 35:6, s. 898-906
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Forskningsöversikt (refereegranskat)abstract
- The Ultrasound Velocity Profiling (UVP) technique allows real-time, non-invasive flow mapping of a fluid along a 1D-measuring line. This study explores the possibility of using the UVP technique and X-ray video-fluoroscopy (XVF) to elucidate the deglutition process with the focus on bolus rheology. By positioning the UVP probe so that the pulsed ultrasonic beam passes behind the air-filled trachea, the bolus flow in the pharynx can be measured. Healthy subjects in a clinical study swallowed fluids with different rheological properties: Newtonian (constant shear viscosity and non-elastic); Boger (constant shear viscosity and elastic); and shear thinning (shear rate-dependent shear viscosity and elastic). The results from both the UVP and XVF reveal higher velocities for the shear thinning fluid, followed by the Boger and the Newtonian fluids, demonstrating that the UVP method has equivalent sensitivities for detecting the velocities of fluids with different rheological properties. The velocity of the contraction wave that clears the pharynx was measured in the UVP and found to be independent of bolus rheology. The results show that UVP not only assesses accurately the fluid velocity in a bolus flow, but it can also monitor the structural changes that take place in response to a bolus flow, with the added advantage of being a completely non-invasive technique that does not require the introduction of contrast media.
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