| 1. |
- Wiklund, Lars, et al.
(författare)
-
Neuro- and cardioprotective effects of blockade of nitric oxide action by administration of methylene blue
- 2007
-
Ingår i: Neuroprotective agents. - : Wiley. - 9781573316859 ; , s. 231-244
-
Konferensbidrag (refereegranskat)abstract
- Methylene blue (MB), generic name methylthioninium (C16H18ClN3 S · 3H2O), is a blue dye synthesized in 1876 by Heinrich Caro for use as a textile dye and used in the laboratory and clinically since the 1890s, with well-known toxicity and pharmacokinetics. It has experimentally proven neuroprotective and cardioprotective effects in a porcine model of global ischemia–reperfusion in experimental cardiac arrest. This effect has been attributed to MB's blocking effect on nitric oxide synthase and guanylyl cyclase, the latter blocking the synthesis of the second messenger of nitric oxide. The physiological effects during reperfusion include stabilization of the systemic circulation without significantly increased total peripheral resistance, moderately increased cerebral cortical blood flow, a decrease of lipid peroxidation and inflammation, and less anoxic tissue injury in the brain and the heart. The last two effects are recorded as less increase in plasma concentrations of astroglial protein S-100β, as well as troponin I and creatine kinase isoenzyme MB, respectively.
|
|
| 2. |
- Nordberg, Klas, 1963-, et al.
(författare)
-
Vision for a UAV helicopter
- 2002
-
Ingår i: International Conference on Intelligent Robots and Systems (IROS), Workshop on Aerial Robotics.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- This paper presents and overview of the basic and applied research carried out by the Computer Vision Laboratory, Linköping University, in the WITAS UAV Project. This work includes customizing and redesigning vision methods to fit the particular needs and restrictions imposed by the UAV platform, e.g., for low-level vision, motion estimation, navigation, and tracking. It also includes a new learning structure for association of perception-action activations, and a runtime system for implementation and execution of vision algorithms. The paper contains also a brief introduction to the WITAS UAV Project.
|
|
