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Regional changes in...
Regional changes in cerebral blood flow oxygenation can indicate global changes in cerebral blood flow during coronary artery occlusion in juvenile pigs
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- Svenmarker, Staffan (författare)
- Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap
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- Häggmark, S. (författare)
- Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap
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- Johansson, Göran (författare)
- Umeå universitet,Anestesiologi och intensivvård
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- Axelsson, Birger, 1957- (författare)
- Region Örebro län,Department of Cardiothoracic Surgery and Anaesthesiology, Örebro University Hospital, Örebro, Sweden
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- Wiklund, Urban (författare)
- Umeå universitet,Radiofysik
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- Haney, Michael (författare)
- Umeå universitet,Anestesiologi och intensivvård
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(creator_code:org_t)
- 2014-06-05
- 2014
- Engelska.
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Ingår i: Physiological Measurement. - : IOP Publishing Ltd. - 0967-3334 .- 1361-6579. ; 35:7, s. 1439-1450
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Near infrared spectroscopy (NIRS) is a widely employed method for assessment of regional cerebral oxygenation (R(c)StO(2)). RcStO(2) values are expected to vary with changes in the relative amount of oxyhaemoglobin. The present experimental study aimed to assess the response of RcStO(2) to controlled alterations of carotid blood flow (CQ). Landrace pigs were anesthetized followed by surgical preparation. Cyclic variations in cardiac output were accomplished by intermittently occluding the main stem of the left coronary artery. A flow measurement probe for assessing CQ was placed around the left carotid artery. One NIRS probe was placed on the left ipsilateral forehead to assess regional cerebral oximetry. Simultaneous registration of CQ and RcStO(2) was conducted. There was a strong correlation for variation in CQ and RcStO(2) signal values. Based on coherence analysis the fraction of power of the RcStO(2) that was coherent with the CQ signal reached 0.84 - 0.12 (P < 0.05) for frequencies lower than 0.1 Hz. The agreement of the sampleto- sample co-variation, as assessed by the Pearson correlation coefficient, was 0.83 +/- 0.08 (P < 0.05). One explanatory component for variations in cerebral oxygenation verified by NIRS should be attributed to variations in the cerebral blood flow.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Fysiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Physiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Nyckelord
- cerebral oxygenation
- near infrared spectroscopy
- blood flow
- measurement
- non-invasive monitoring
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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