SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Wu Ji) "

Sökning: WFRF:(Wu Ji)

Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  •  
2.
  • Wang, Zhaoming, et al. (författare)
  • Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33
  • 2014
  • Ingår i: Human Molecular Genetics. - 0964-6906 .- 1460-2083. ; 23:24, s. 6616-6633
  • Tidskriftsartikel (refereegranskat)abstract
    • Genome-wide association studies (GWAS) have mapped risk alleles for at least 10 distinct cancers to a small region of 63 000 bp on chromosome 5p15.33. This region harbors the TERT and CLPTM1L genes; the former encodes the catalytic subunit of telomerase reverse transcriptase and the latter may play a role in apoptosis. To investigate further the genetic architecture of common susceptibility alleles in this region, we conducted an agnostic subset-based meta-analysis (association analysis based on subsets) across six distinct cancers in 34 248 cases and 45 036 controls. Based on sequential conditional analysis, we identified as many as six independent risk loci marked by common single-nucleotide polymorphisms: five in the TERT gene (Region 1: rs7726159, P = 2.10 × 10(-39); Region 3: rs2853677, P = 3.30 × 10(-36) and PConditional = 2.36 × 10(-8); Region 4: rs2736098, P = 3.87 × 10(-12) and PConditional = 5.19 × 10(-6), Region 5: rs13172201, P = 0.041 and PConditional = 2.04 × 10(-6); and Region 6: rs10069690, P = 7.49 × 10(-15) and PConditional = 5.35 × 10(-7)) and one in the neighboring CLPTM1L gene (Region 2: rs451360; P = 1.90 × 10(-18) and PConditional = 7.06 × 10(-16)). Between three and five cancers mapped to each independent locus with both risk-enhancing and protective effects. Allele-specific effects on DNA methylation were seen for a subset of risk loci, indicating that methylation and subsequent effects on gene expression may contribute to the biology of risk variants on 5p15.33. Our results provide strong support for extensive pleiotropy across this region of 5p15.33, to an extent not previously observed in other cancer susceptibility loci.
  •  
3.
  • Ablikim, M., et al. (författare)
  • Observation of the decay psi(3686) -> Lambda(Sigma)over-bar(+/-) pi(-/+) + c.c
  • 2013
  • Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 88:11, s. 112007-
  • Tidskriftsartikel (refereegranskat)abstract
    • Using a sample of 1:06 X 10(8) psi(3686) events collected with the BESIII detector, we present the first observation of the decays of psi(3686) -> Lambda(Sigma) over bar (+) pi(-) + c.c. and psi(3686) -> Lambda(Sigma) over bar (-) pi(+) + c.c. The branching fractions are measured to be B(psi(3686) -> Lambda(Sigma) over bar (+) pi(-) + c.c.) = (1.40 +/- 0.03 +/- 0.13) X 10(-4) and B(psi(3686) -> Lambda (Sigma) over bar (-) pi(+) + c.c.) = (1.54 +/- 0.04 +/- 0.13) X 10(-4) where the first errors are statistical and the second ones systematic.
  •  
4.
  • Campbell, PJ, et al. (författare)
  • Pan-cancer analysis of whole genomes
  • 2020
  • Ingår i: Nature. - : Nature Publishing Group. - 1476-4687 .- 0028-0836. ; 578:7793, s. 82-
  • Tidskriftsartikel (refereegranskat)
  •  
5.
  • Ablikim, M., et al. (författare)
  • Precision measurements of B(D+ -> mu(+)nu(mu)), the pseudoscalar decay constant fD+, and the quark mixing matrix element vertical bar V-cd vertical bar
  • 2014
  • Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 89:5, s. 051104-
  • Tidskriftsartikel (refereegranskat)abstract
    • We report a measurement of the branching fraction B(D+ -> mu(+)nu(mu)) = [3.71 +/- 0.19(stat) +/- 0.06(sys)] x 10(-4) based on 2.92 fb(-1) of data accumulated at root s = 3.773 GeV with the BESIII detector at the BEPCII collider. This measurement, in conjunction with the Cabibbo-Kobayashi-Maskawa matrix element vertical bar V-cd vertical bar determined from a global Standard Model fit, implies a value for the weak decay constant f(D+) = (203.2 +/- 5.3 +/- 1.8) MeV. Additionally, using this branching fraction measurement together with a lattice QCD prediction for f(D+), we find vertical bar V-cd vertical bar 0.2210 +/- 0.0058 +/- 0.0047. In either case, these are the most precise results for these quantities to date.
  •  
6.
  • Ablikim, M., et al. (författare)
  • Search for eta(c)(2S)h(c) -> p(p)over-bar decays and measurements of the chi(cJ) -> p(p)over-bar branching fractions
  • 2013
  • Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 88:11, s. 112001-
  • Tidskriftsartikel (refereegranskat)abstract
    • Using a sample of 1.06 x 10(8)psi(3686) events collected with the BESIII detector at BEPCII, the decays eta(c)(2S) -> p (p) over bar and h(c) -> p (p) over bar are searched for, where eta(c)(2S) and h(c) are reconstructed in the decay chains psi(3686) -> gamma eta(c)(2S), eta(c)(2S) -> p (p) over bar and psi(3686) -> pi(0)h(c), h(c) -> p (p) over bar, respectively. No significant signals are observed. The upper limits of the product branching fractions are determined to be B(psi(3686) -> gamma eta(c)(2S)) x B(eta(c)(2S) -> p (p) over bar) < 1.4 x 10(-6) and B(psi(3686) -> pi(0)h(c)) x B(h(c) -> p<(p)over bar>) < 1.3 x 10(-7) at the 90% C.L.. The branching fractions for chi(cJ) -> p<(p)over bar> (J = 0, 1, 2) are also measured to be (24.5 +/- 0.8 +/- 1.3, 8.6 +/- 0.5 +/- 0.5, 8.4 +/- 0.5 +/- 0.5) x 10(-5), which are the world's most precise measurements.
  •  
7.
  • Sampson, Joshua N., et al. (författare)
  • Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for 13 Cancer Types
  • 2015
  • Ingår i: Journal of the National Cancer Institute. - 0027-8874 .- 1460-2105. ; 107:12
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Studies of related individuals have consistently demonstrated notable familial aggregation of cancer. We aim to estimate the heritability and genetic correlation attributable to the additive effects of common single-nucleotide polymorphisms (SNPs) for cancer at 13 anatomical sites.Methods: Between 2007 and 2014, the US National Cancer Institute has generated data from genome-wide association studies (GWAS) for 49 492 cancer case patients and 34 131 control patients. We apply novel mixed model methodology (GCTA) to this GWAS data to estimate the heritability of individual cancers, as well as the proportion of heritability attributable to cigarette smoking in smoking-related cancers, and the genetic correlation between pairs of cancers.Results: GWAS heritability was statistically significant at nearly all sites, with the estimates of array-based heritability, h(l)(2), on the liability threshold (LT) scale ranging from 0.05 to 0.38. Estimating the combined heritability of multiple smoking characteristics, we calculate that at least 24% (95% confidence interval [CI] = 14% to 37%) and 7% (95% CI = 4% to 11%) of the heritability for lung and bladder cancer, respectively, can be attributed to genetic determinants of smoking. Most pairs of cancers studied did not show evidence of strong genetic correlation. We found only four pairs of cancers with marginally statistically significant correlations, specifically kidney and testes (rho = 0.73, SE = 0.28), diffuse large B-cell lymphoma (DLBCL) and pediatric osteosarcoma (rho = 0.53, SE = 0.21), DLBCL and chronic lymphocytic leukemia (CLL) (rho = 0.51, SE = 0.18), and bladder and lung (rho = 0.35, SE = 0.14). Correlation analysis also indicates that the genetic architecture of lung cancer differs between a smoking population of European ancestry and a nonsmoking Asian population, allowing for the possibility that the genetic etiology for the same disease can vary by population and environmental exposures.Conclusion: Our results provide important insights into the genetic architecture of cancers and suggest new avenues for investigation.
  •  
8.
  • Ablikim, M., et al. (författare)
  • Amplitude analysis of the D+ -> K-S(0)pi + (0)(pi) Dalitz plot
  • 2014
  • Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 89:5, s. 052001-
  • Tidskriftsartikel (refereegranskat)abstract
    • We perform an analysis of the D+ -> K-S(0)pi + (0)(pi) Dalitz plot using a data set of 2.92 fb(-1) of e(+) e(-) collisions at the (3770) mass accumulated by the BESIII experiment, in which 166694 candidate events are selected with a background of 15.1%. The Dalitz plot is found to be well represented by a combination of six quasitwo- body decay channels [k(SP)(0)(+) (1450)(+,) ] plus a small nonresonant component. Using the fit fractions from this analysis, partial branching ratios are updated with higher precision than previous measurements.
  •  
9.
  • Ablikim, M., et al. (författare)
  • Measurement of chi(cJ) decaying into eta ' K+K-
  • 2014
  • Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 89:7, s. 074030-
  • Tidskriftsartikel (refereegranskat)abstract
    • Using (106.41 +/- 0.86) x 10(6) Psi(3686) events collected with the BESIII detector at BEPCII, we study for the first time the decay chi(cJ) -> eta'K+K- (J = 1, 2), where eta' -> gamma rho(0) and eta' -> eta pi(+)pi(-). A partial wave analysis in the covariant tensor amplitude formalism is performed for the decay chi(c1) -> eta'K+K-. Intermediate processes chi(c1) -> eta'f(2)'(1525) chi(c1) -> K-0*(1430)K-+/-(-/+) (K-0*(1430)(+/-) -> eta'K-+/-) are observed with statistical significances larger than 5 sigma, and their branching fractions are measured.
  •  
10.
  • Ablikim, M., et al. (författare)
  • Measurement of the branching fraction for psi(3686) -> omega K+K-
  • 2014
  • Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 89:11, s. 112006-
  • Tidskriftsartikel (refereegranskat)abstract
    • With 1.06 x 10(8) psi(3686) events collected with the BESIII detector, the branching fraction of psi(3686) -> omega K+K- is measured to be (1.54 +/- 0.04 +/- 0.11) x 10(-4). This is the most precise result to date, due to the largest psi(3686) sample, improved signal reconstruction efficiency, good simulation of the detector performance, and a more accurate knowledge of the continuum contribution. Using the branching fraction of J/psi -> omega K+K-, the ratio B(psi(3868) -> K+K-)/B(J/psi -> K+K-) is determined to be (18.4 +/- 3.7)%. This constitutes a significantly improved test of the 12% rule, with the uncertainty now dominated by the J/psi branching fraction.
  •  
Skapa referenser, mejla, bekava och länka
Typ av publikation
tidskriftsartikel (770)
konferensbidrag (4)
forskningsöversikt (3)
annan publikation (1)
doktorsavhandling (1)
Typ av innehåll
refereegranskat (774)
övrigt vetenskapligt (5)
Författare/redaktör
Fang, Y. (612)
Zhemchugov, A. (610)
Jin, S. (606)
Cetin, S. A. (604)
Ouyang, Q. (601)
Cakir, O. (597)
visa fler...
Ma, L. L. (590)
Chen, X. (580)
Liu, J. B. (570)
Aad, G (565)
Liu, D. (561)
Zhang, J. (552)
Yang, Y. (542)
Berger, N. (525)
Zwalinski, L. (508)
Peters, K. (508)
Chen, S. (497)
Bai, Y. (488)
Werner, M. (478)
Zhou, B. (477)
Wang, J. (471)
Zhu, H. (469)
Chen, H. (468)
Li, H. (468)
Wang, H. (468)
Wu, X. (468)
Yang, H. (468)
Francis, D. (467)
Ishino, M. (466)
Sliwa, K. (466)
Yu, J. (466)
Blumenschein, U. (465)
Cranmer, K. (465)
Etzion, E. (465)
Fukunaga, C. (465)
Hasegawa, Y. (465)
Kawagoe, K. (465)
Kawamoto, T. (465)
Kobayashi, T. (465)
Martin, B. (465)
Meyer, J. (465)
Navarro, G. (465)
Quadt, A. (465)
Su, D. (465)
Tanaka, S. (465)
Tarem, S. (465)
Vachon, B. (465)
Walker, R. (465)
Wilson, A. (465)
Wu, S. L. (465)
visa färre...
Lärosäte
Lunds universitet (493)
Kungliga Tekniska Högskolan (414)
Uppsala universitet (203)
Karolinska Institutet (80)
Umeå universitet (27)
Stockholms universitet (23)
visa fler...
Luleå tekniska universitet (16)
Linköpings universitet (10)
Göteborgs universitet (8)
Högskolan Dalarna (7)
Chalmers tekniska högskola (5)
Mälardalens högskola (2)
Örebro universitet (2)
Linnéuniversitetet (2)
Jönköping University (1)
Högskolan i Skövde (1)
visa färre...
Språk
Engelska (778)
Kinesiska (1)
Forskningsämne (UKÄ/SCB)
Naturvetenskap (636)
Medicin och hälsovetenskap (86)
Teknik (27)
Samhällsvetenskap (3)
Lantbruksvetenskap (1)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy