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Sökning: WFRF:(Yan J) > Mälardalens universitet

  • Resultat 1-10 av 83
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1.
  • Duggan, D., et al. (författare)
  • Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP
  • 2007
  • Ingår i: Journal of the National Cancer Institute. - : Oxford University Press (OUP). - 0027-8874 .- 1460-2105. ; 99:24, s. 1836-1844
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: The consistent finding of a genetic susceptibility to prostate cancer suggests that there are germline sequence variants predisposing individuals to this disease. These variants could be useful in screening and treatment. Methods: We performed an exploratory genome-wide association scan in 498 men with aggressive prostate cancer and 494 control subjects selected from a population-based case-control study in Sweden. We combined the results of this scan with those for aggressive prostate cancer from the publicly available Cancer Genetic Markers of Susceptibility (CGEMS) Study. Single-nucleotide polymorphisms (SNPs) that showed statistically significant associations with the risk of aggressive prostate cancer based on two-sided allele tests were tested for their association with aggressive prostate cancer in two independent study populations composed of individuals of European or African American descent using one-sided tests and the genetic model (dominant or additive) associated with the lowest value in the exploratory study. Results: Among the approximately 60000 SNPs that were common to our study and CGEMS, we identified seven that had a similar (positive or negative) and statistically significant (P<.01) association with the risk of aggressive prostate cancer in both studies. Analysis of the distribution of these SNPs among 1032 prostate cancer patients and 571 control subjects of European descent indicated that one, rs1571801, located in the DAB2IP gene, which encodes a novel Ras GTPase-activating protein and putative prostate tumor suppressor, was associated with aggressive prostate cancer (one-sided P value =. 004). The association was also statistically significant in an African American study population that included 210 prostate cancer patients and 346 control subjects (one-sided P value =. 02). Conclusion: A genetic variant in DAB2IP may be associated with the risk of aggressive prostate cancer and should be evaluated further.
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2.
  • Ding, J., et al. (författare)
  • Theoretical prediction of the local structures and transport properties of binary alkali chloride salts for concentrating solar power
  • 2017
  • Ingår i: Nano Energy. - : Elsevier. - 2211-2855 .- 2211-3282. ; 39, s. 380-389
  • Tidskriftsartikel (refereegranskat)abstract
    • Comprehensive molecular simulations have been carried out to compute local structures and transport properties of different components of binary NaCl-KCl over a wide operating temperature range. The partial radial distribution functions, coordination number curves and angular distribution functions were calculated to analyze the influence of temperature and component on local structures of molten Alkali Chlorides. Transport properties were calculated by using reverse non-equilibrium molecular dynamics (RNEMD) simulations including densities, shear viscosity and thermal conductivity. The results show that ion clusters are considered to be formed and the distance of ion clusters become larger with increasing temperature which has great influence on macro-properties. The calculated properties have a good agreement with the experimental data, and similar method could be used to computationally calculate the properties of various molten salts and their mixtures.
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3.
  • Jian, J., et al. (författare)
  • Multi-stage supply restoration of active distribution networks with SOP integration
  • 2022
  • Ingår i: Sustainable Energy, Grids and Networks. - : Elsevier Ltd. - 2352-4677. ; 29
  • Tidskriftsartikel (refereegranskat)abstract
    • Supply restoration from outages is essential for improving the reliability of active distribution networks (ADNs) after fault isolation. Soft open point (SOP) can adjust the power flow among feeders and provide voltage support for power outage areas. Considering the sequential coordination of switching operation and SOP control mode selection, a multi-stage supply restoration method with SOPs is proposed for ADNs. First, the sequential energization is formulated, in which the impact of SOP control mode on restoration sequence is analyzed. By providing voltage support, the coordination of SOPs will rapidly energize the outage area and improve the voltage profile. Then, a multi-stage restoration model with SOPs is proposed, in which reconfiguration of switches and control mode selection of SOPs are coordinated in sequence to maximize the load recovery level of ADNs. Through the switching action-time mapping, secure operation is ensured during the entire supply restoration process. Finally, the effectiveness of the proposed method is validated on a modified IEEE 33-node distribution system and practical distribution networks with four-terminal SOP. Results show that the proposed method can fully exploit the potential benefits of SOPs and effectively enhance the load recovery level of ADNs.
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4.
  • Jiang, Mingkun, et al. (författare)
  • Using Existing Infrastructure to Realize Low-Cost and Flexible Photovoltaic Power Generation in Areas with High-Power Demand in China
  • 2020
  • Ingår i: iScience. - : Elsevier Inc.. - 2589-0042. ; 23:12
  • Tidskriftsartikel (refereegranskat)abstract
    • Energy Policy; Energy Resources; Energy Systems; Energy Management © 2020 This study develops a new concept involving using the existing infrastructure for photovoltaic (PV) generation to reduce the costs associated with increased land use and to avoid curtailment due to the mismatch between power supply and demand. We establish a method to estimate the technological potential and economic performance of the PV systems deployed in coal-fired power plants in China. The potential capacity of the examined 1,082 units in China reaches 4 GWe, which is equivalent to 32% of China's newly installed distributed PV capacity in 2019. A total of 87% of PV systems achieve plant-side grid parity compared with desulfurized coal benchmark electricity prices. To the best of our knowledge, this is the first study that investigates the use of rooftops and coal storage sheds in power plants to facilitate low-cost, flexible PV power generation, thus opening a new channel for future PV generation development.
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6.
  • Wang, F., et al. (författare)
  • A comprehensive review on high-temperature fuel cells with carbon capture
  • 2020
  • Ingår i: Applied Energy. - : Elsevier Ltd. - 0306-2619 .- 1872-9118. ; 275
  • Forskningsöversikt (refereegranskat)abstract
    • High-temperature fuel cells and their hybrid systems represent one of the most promising technologies with high conversion efficiency. The configuration of such kind of system could facilitate an easy capture of CO2. Several novel CO2 capture strategies have been developed based on high-temperature fuel cells, such as solid oxide fuel cell (SOFC), molten carbonate fuel cell (MCFC) and direct carbon fuel cell (DCFC). However, related review which focus on their system integration and performance evaluation is still rare. The aim of this study is to improve interest in high-temperature fuel cell with CO2 capture by providing an overview of the status of such kind of cutting-edge technologies. To approach this goal, the major strategies and technologies for fuel cells and their hybrid system with CO2 capture have been reviewed. Simultaneously, the characteristics of fuel cell technologies are summarized and the technical and economic performance of the fuel cell with CO2 capture are explored and discussed as well. The existing challenges that required to be overcome in fuel cell with CO2 capture technology are highlighted with aspects on fuel cell module scale-up, cost, safety, reliability and capture energy, etc. Finally, opportunities for the future development of high-temperature fuel cell with CO2 capture technologies are discussed. The conclusion remarks of this investigation indicate that fuel cell integrating CO2 capture process is a promising route to sustainable future, and could even be more effective if fuel cell technology can be commercialized.
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7.
  • Wang, W., et al. (författare)
  • Carbon dioxide adsorption thermodynamics and mechanisms on MCM-41 supported polyethylenimine prepared by wet impregnation method
  • 2015
  • Ingår i: Applied Energy. - : Elsevier BV. - 0306-2619 .- 1872-9118. ; 142, s. 221-228
  • Tidskriftsartikel (refereegranskat)abstract
    • Amine-functionalized sorbents prepared by wet impregnation method shows great promises for CO2 capture from real flue gas in power plants. The objective of this work is to understand CO2 adsorption thermodynamics and mechanisms at varied polyethylenimine (PEI) loadings on mesoporous MCM-41 by wet impregnation method using a computational approach for the first time. The structures of PEI/MCM-41 sorbents were optimized using molecular dynamics (MD), and the CO2 adsorption thermodynamics at varied PEI loadings was simulated using Grand Canonical Monte Carlo (GCMC) method. Results showed a good agreement between experiments and simulation. On the surface of the MCM-41, there are high CO2-philic sites for CO2 adsorption, which were firstly covered by PEI molecular. The functionalization groups increased the interactions of the CO2 with more PEI molecular deployed on the surface of the MCM-41, then to the center of the pore. The adsorption performance of the composite sorbents depended on the adsorption cites and the space for CO2 diffusion. The CO2 adsorption thermodynamics and mechanisms at varied PEI loadings shed lights on tuning CO2 capture performance with amine-functionalized sorbents for power plant greenhouse gas control.
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8.
  • Campana, Pietro Elia, et al. (författare)
  • Economic optimization of photovoltaic water pumping systems for irrigation
  • 2015
  • Ingår i: Energy Conversion and Management. - : Elsevier BV. - 0196-8904 .- 1879-2227. ; 95, s. 32-41
  • Tidskriftsartikel (refereegranskat)abstract
    • Photovoltaic water pumping technology is considered as a sustainable and economical solution to provide water for irrigation, which can halt grassland degradation and promote farmland conservation in China. The appropriate design and operation significantly depend on the available solar irradiation, crop water demand, water resources and the corresponding benefit from the crop sale. In this work, a novel optimization procedure is proposed, which takes into consideration not only the availability of ground-water resources and the effect of water supply on crop yield, but also the investment cost of photovoltaic water pumping system and the revenue from crop sale. A simulation model, which combines the dynamics of photovoltaic water pumping system, groundwater level, water supply, crop water demand and crop yield, is employed during the optimization. To prove the effectiveness of the new optimization approach, it has been applied to an existing photovoltaic water pumping system. Results show that the optimal configuration can guarantee continuous operations and lead to a substantial reduction of photovoltaic array size and consequently of the investment capital cost and the payback period. Sensitivity studies have been conducted to investigate the impacts of the prices of photovoltaic modules and forage on the optimization. Results show that the water resource is a determinant factor.
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9.
  • Campana, Pietro Elia, et al. (författare)
  • Managing agricultural drought in Sweden using a novel spatially-explicit model from the perspective of water-food-energy nexus
  • 2018
  • Ingår i: Journal of Cleaner Production. - : Elsevier. - 0959-6526 .- 1879-1786. ; 197, s. 1382-1393
  • Tidskriftsartikel (refereegranskat)abstract
    • Using a multi-disciplinary approach, this paper integrated spatial analysis with agricultural and energy system modelling to assess the impacts of drought on crop water demand, water availability, crop yield, and electricity requirements for irrigation. This was done by a novel spatially-explicit and integrated water-food-energy nexus model, using the spatial climatic data generated by the mesoscale MESAN and STRANG models. In this study, the model was applied to quantify the effects of drought on the Swedish irrigation sector in 2013, a typical drought year, for a specific crop. The results show that drought can severely affect the crop yield if irrigation is not applied, with a peak yield reduction of 18 t/ha, about 50 % loss as compared to the potential yield in irrigated conditions. Accordingly, the water and energy requirements for irrigation to halt the negative drought effects and maintain high yields are significant, with the peaks up to 350 mm and 700 kWh per hectare. The developed model can be used to provide near real-time guidelines for a comprehensive drought management system. The model also has significant potentials for applications in precision agriculture, especially using high-resolution satellite data.
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10.
  • Campana, Pietro Elia, et al. (författare)
  • Suitable and optimal locations for implementing photovoltaic water pumping systems for grassland irrigation in China
  • 2017
  • Ingår i: APPLIED ENERGY. - : Elsevier BV. - 0306-2619 .- 1872-9118. ; 185, s. 1879-1889
  • Tidskriftsartikel (refereegranskat)abstract
    • Grassland plays a key role for the food security of China because of the large number of livestock raised in those areas. Thus, grassland degradation due to climate change and overgrazing is considered as one of the most severe environmental and economic threat for the future sustainable development of China. Photovoltaic water pumping systems for irrigation can play a fundamental role for the conservation of grassland areas. This paper investigates the geospatial distribution of the technically suitable grassland locations for the implementation of photovoltaic water pumping systems. The technically suitable grassland areas were taken as starting point to assess the optimal locations. The assessment of the optimal locations was conducted using a spatially explicit optimization model of renewable energy systems based on the cost minimization of the whole forage supply chain. The results indicate that the photovoltaic water pumping systems provide high potential for improving forage productivity, contributing to meet the local demand. The optimal areas are highly sensitive to several environmental and economic parameters such as increased forage potential yield, forage management costs, forage water requirements, ground water depth, forage price and CO2 price. Most of the optimal areas are selected when the market forage price ranges from 300 to 500 $/tonne DM, indicating that the forage produced using PVWP technology for irrigation is already competitive compared to the imported forage.
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