Tyck till om SwePub Sök
här!
Search: WFRF:(Yarom N)
> English
> Fullerton A. >
Methodological appr...
Methodological approach for determining the Minimal Important Difference and Minimal Important Change scores for the European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module (EORTC QLQ-HN43) exemplified by the Swallowing scale
-
Singer, S. (author)
-
- Hammerlid, Eva, 1957 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology
-
Tomaszewska, I. M. (author)
-
show more...
-
Amdal, C. D. (author)
-
Bjordal, K. (author)
-
Herlofson, B. B. (author)
-
Santos, M. (author)
-
Silva, J. C. (author)
-
Mehanna, H. (author)
-
Fullerton, A. (author)
-
Brannan, C. (author)
-
Gonzalez, L. F. (author)
-
Inhestern, J. (author)
-
Pinto, M. (author)
-
Arraras, J. I. (author)
-
Yarom, N. (author)
-
Bonomo, P. (author)
-
Baumann, I. (author)
-
Galalae, R. (author)
-
Nicolatou-Galitis, O. (author)
-
Kiyota, N. (author)
-
Raber-Durlacher, J. (author)
-
Salem, D. (author)
-
Fabian, A. (author)
-
Boehm, A. (author)
-
Krejovic-Trivic, S. (author)
-
Chie, W. C. (author)
-
Taylor, K. (author)
-
Simon, C. (author)
-
Licitra, L. (author)
-
Sherman, A. C. (author)
-
Eortc Quality Life Grp, Eortc Quality Life Grp (author)
-
Eortc Head Neck Canc Grp, Eortc Head Neck Canc Grp (author)
-
show less...
-
(creator_code:org_t)
- 2021-07-16
- 2022
- English.
-
In: Quality of Life Research. - : Springer Science and Business Media LLC. - 0962-9343 .- 1573-2649. ; 31, s. 841-853
- Related links:
-
https://link.springe...
-
show more...
-
https://gup.ub.gu.se...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Purpose The aim of this study was to explore what methods should be used to determine the minimal important difference (MID) and minimal important change (MIC) in scores for the European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ-HN43. Methods In an international multi-centre study, patients with head and neck cancer completed the EORTC QLQ-HN43 before the onset of treatment (t1), three months after baseline (t2), and six months after baseline (t3). The methods explored for determining the MID were: (1) group comparisons based on performance status; (2) 0.5 and 0.3 standard deviation and standard error of the mean. The methods examined for the MIC were patients' subjective change ratings and receiver-operating characteristics (ROC) curves, predictive modelling, standard deviation, and standard error of the mean. The EORTC QLQ-HN43 Swallowing scale was used to investigate these methods. Results From 28 hospitals in 18 countries, 503 patients participated. Correlations with the performance status were |r|< 0.4 in 17 out of 19 scales; hence, performance status was regarded as an unsuitable anchor. The ROC approach yielded an implausible MIC and was also discarded. The remaining approaches worked well and delivered MID values ranging from 10 to 14; the MIC for deterioration ranged from 8 to 16 and the MIC for improvement from - 3 to - 14. Conclusions For determining MIDs of the remaining scales of the EORTC QLQ-HN43, we will omit comparisons of groups based on the Karnofsky Performance Score. Other external anchors are needed instead. Distribution-based methods worked well and will be applied as a starting strategy for analyses. For the calculation of MICs, subjective change ratings, predictive modelling, and standard-deviation based approaches are suitable methods whereas ROC analyses seem to be inappropriate.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- Minimal important difference
- Minimal important change
- MCID
- Clinical significance
- Subjective significance
- EORTC QLQ-HN43
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Singer, S.
-
Hammerlid, Eva, ...
-
Tomaszewska, I. ...
-
Amdal, C. D.
-
Bjordal, K.
-
Herlofson, B. B.
-
show more...
-
Santos, M.
-
Silva, J. C.
-
Mehanna, H.
-
Fullerton, A.
-
Brannan, C.
-
Gonzalez, L. F.
-
Inhestern, J.
-
Pinto, M.
-
Arraras, J. I.
-
Yarom, N.
-
Bonomo, P.
-
Baumann, I.
-
Galalae, R.
-
Nicolatou-Galiti ...
-
Kiyota, N.
-
Raber-Durlacher, ...
-
Salem, D.
-
Fabian, A.
-
Boehm, A.
-
Krejovic-Trivic, ...
-
Chie, W. C.
-
Taylor, K.
-
Simon, C.
-
Licitra, L.
-
Sherman, A. C.
-
Eortc Quality Li ...
-
Eortc Head Neck ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cancer and Oncol ...
- Articles in the publication
-
Quality of Life ...
- By the university
-
University of Gothenburg